Clusters of Characterized Proteins

Clustering the characterized proteins for asd-S-perS (L-aspartate semialdehyde sulfurtransferase, persulfide-forming component) in L-methionine biosynthesis

Or see other characterized proteins similar to asd-S-perS

Or see all steps for L-methionine biosynthesis

Or cluster curated proteins matching a keyword

Definition of asd-S-perS

• UniProt sequence Y1715_METAC: RecName: Full=UPF0280 protein MA_1715 {ECO:0000255|HAMAP-Rule:MF_01079};
• Curated sequence 8499265: Homocysteine formation from aspartate semialdehyde (COG2122 or apbE like component)
• Predicted: UniProt sequence F2LX84: SubName: Full=ApbE family lipoprotein {ECO:0000313|EMBL:AEA33142.1};
• Comment: The putative persulfide forming component is MA1715 or DvMF_0044 (see PMID:25315403 and PMC5764234). A conserved cysetien in MA1821 is modified to a persulfide in vivo (PMID:28165724). This component is not 100% required in Methanosarcina acetivorans (possible redundancy). In Hippea alviniae, this protein (G415_RS0107280, similar to F2LX84) is diverged but is in an operon with the other components.

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 235-253 amino acids (not heteromeric)

F2LX84 ApbE family lipoprotein
235 amino acids: PaperBLAST, CDD, Compare to cluster

Y1715_METAC UPF0280 protein MA_1715 {ECO:0000255|HAMAP-Rule:MF_01079}
253 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (1/1 heteromeric)

DvMF_0044 Homocysteine formation from aspartate semialdehyde (COG2122 or apbE like component) from Desulfovibrio vulgaris Miyazaki F
Heteromeric, 277 amino acids: PaperBLAST, CDD