Clusters of Characterized Proteins

GapMind for Amino acid biosynthesis

Clusters of Characterized Proteins

Clustering the characterized proteins for argD (N-acetylornithine aminotransferase) in L-proline biosynthesis

Or see other characterized proteins similar to argD

Or see all steps for L-proline biosynthesis

Or cluster curated proteins matching a keyword

Definition of argD

Curated proteins or TIGRFams with EC 2.6.1.11
Ignore hits to items matching EC 2.6.1.81 when looking for 'other' hits
Ignore hits to items matching EC 2.6.1.19 when looking for 'other' hits
Ignore hits to MONOMER-18314 when looking for 'other' hits ([amino group carrier protein]-C-terminal-L-glutamyl-γ-L-lysine aminotransferase (EC 2.6.1.118; EC 2.6.1.124))
Ignore hits to items matching EC 2.6.1.48 when looking for 'other' hits
UniProt sequence A0A806JQF3: RecName: Full=Acetylornithine aminotransferase {ECO:0000256|HAMAP-Rule:MF_01107}; Short=ACOAT {ECO:0000256|HAMAP-Rule:MF_01107}; EC=2.6.1.11 {ECO:0000256|HAMAP-Rule:MF_01107};
Comment: This aminotransferase for converting N-acetylglutamate semialdehyde to acetylornithine is often similar to succinylornithine transaminases (EC 2.6.1.81), 4-aminobutyrate aminotransferases (EC 2.6.1.19), or 5-aminovalerate transaminases (EC 2.6.1.48). (Succinylornithine and 4-aminobutyrate transaminases are also reported to be active on N-acetylornithine and this seems likely for 5-aminovalerate transaminases as well.) link is given this EC nmber but is actually LysW-lysine/ornithine aminotransferase (LysJ). PMID:A0A806JQF3 show that Rv1655 (A0A806JQF3) from Mycobacterium tuberculosis is argD.

Fetched 14 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 14 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 389-460 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

A8J933 acetylornithine transaminase (EC 2.6.1.11) from Chlamydomonas reinhardtii
PFams: Aminotran_3
460 amino acids: PaperBLAST, CDD, Compare to cluster

B1XNF8 acetylornithine transaminase (EC 2.6.1.11); 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19) from Synechococcus sp. PCC 7002
PFams: Aminotran_3
418 amino acids: PaperBLAST, CDD, Compare to cluster

O30508 succinylornithine transaminase subunit (EC 2.6.1.13; EC 2.6.1.11; EC 2.6.1.81) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
ARUC_PSEAE / O30508 Succinylornithine transaminase/acetylornithine aminotransferase; ACOAT; SOAT; Succinylornithine aminotransferase; EC 2.6.1.11; EC 2.6.1.81 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
O30508 succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas aeruginosa
PFams: Aminotran_3, Aminotran_1_2
406 amino acids: PaperBLAST, CDD, Compare to cluster

P73133 bifunctional acetylornithine transaminase/4-aminobutyrate—2-oxoglutarate transaminase (EC 2.6.1.19; EC 2.6.1.11) from Synechocystis sp. (strain PCC 6803 / Kazusa)
P73133 acetylornithine transaminase (EC 2.6.1.11); 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19) from Synechococcus sp. PCC 6803
PFams: Aminotran_3
429 amino acids: PaperBLAST, CDD, Compare to cluster

b1748 succinylornithine transaminase (EC 2.6.1.81; EC 2.6.1.11) from Escherichia coli K-12 substr. MG1655
P77581 succinylornithine transaminase (EC 2.6.1.81; EC 2.6.1.11) from Escherichia coli (strain K12)
ASTC_ECOLI / P77581 Succinylornithine transaminase; SOAT; Carbon starvation protein C; Succinylornithine aminotransferase; EC 2.6.1.81 from Escherichia coli (strain K12)
RF|NP_416262.1 succinylornithine transaminase; EC 2.6.1.81 from Escherichia coli K12
PFams: Aminotran_3, Aminotran_1_2
406 amino acids: PaperBLAST, CDD, Compare to cluster

RF|NP_588255.1 acetylornithine aminotransferase; EC 2.6.1.11 from Schizosaccharomyces pombe
PFams: Aminotran_3
441 amino acids: PaperBLAST, CDD, Compare to cluster

b3359 N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase (EC 2.6.1.11; EC 2.6.1.17) from Escherichia coli K-12 substr. MG1655
P18335 N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase (EC 2.6.1.11; EC 2.6.1.17) from Escherichia coli (strain K12)
ARGD_ECOLI / P18335 Acetylornithine/succinyldiaminopimelate aminotransferase; ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 from Escherichia coli (strain K12)
PFams: Aminotran_3, Aminotran_1_2
406 amino acids: PaperBLAST, CDD, Compare to cluster

P18544 acetylornithine transaminase (EC 2.6.1.11) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
ARGD_YEAST / P18544 Acetylornithine aminotransferase, mitochondrial; ACOAT; EC 2.6.1.11 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Aminotran_3
423 amino acids: PaperBLAST, CDD, Compare to cluster

b2662 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli K-12 substr. MG1655
P22256 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli (strain K12)
GABT_ECOLI / P22256 4-aminobutyrate aminotransferase GabT; 5-aminovalerate transaminase; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBAT; EC 2.6.1.19; EC 2.6.1.48 from Escherichia coli (strain K12)
PFams: Aminotran_3
426 amino acids: PaperBLAST, CDD, Compare to cluster

ARGD_SALTY / P40732 Acetylornithine/succinyldiaminopimelate aminotransferase; ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aminotran_3, Aminotran_1_2
405 amino acids: PaperBLAST, CDD, Compare to cluster

ARGD_ARATH / Q9M8M7 Acetylornithine aminotransferase, chloroplastic/mitochondrial; ACOAT; Acetylornithine transaminase; AOTA; Protein HOPW1-1-INTERACTING 1; EC 2.6.1.11 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Aminotran_3
457 amino acids: PaperBLAST, CDD, Compare to cluster

A0A806JQF3 Acetylornithine aminotransferase {ECO:0000256|HAMAP-Rule:MF_01107}; Short=ACOAT {ECO:0000256|HAMAP-Rule:MF_01107}; EC=2.6.1.11 {ECO:0000256|HAMAP-Rule:MF_01107}
400 amino acids: PaperBLAST, CDD, Compare to cluster

HP15_3042 acetylornithine aminotransferase (EC 2.6.1.11); succinylornithine aminotransferase (EC 2.6.1.81) from Marinobacter adhaerens HP15
PFams: Aminotran_3
404 amino acids: PaperBLAST, CDD, Compare to cluster

AZOBR_RS19025 acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] from Azospirillum brasilense Sp245
PFams: Aminotran_3
389 amino acids: PaperBLAST, CDD, Compare to cluster