GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for proB (glutamate 5-kinase) in L-proline biosynthesis

Or see other characterized proteins similar to proB

Or see all steps for L-proline biosynthesis

Or cluster curated proteins matching a keyword

Definition of proB

Fetched 16 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 16 of these sequences

Found 3 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 344-428 amino acids (not heteromeric)

b0242 glutamate 5-kinase (EC 2.7.2.11) from Escherichia coli K-12 substr. MG1655
P0A7B5 glutamate 5-kinase (EC 2.7.2.11) from Escherichia coli (strain K12)
PROB_ECOLI / P0A7B5 Glutamate 5-kinase; Gamma-glutamyl kinase; GK; EC 2.7.2.11 from Escherichia coli (strain K12)
P0A7B5 glutamate 5-kinase (EC 2.7.2.11) from Escherichia coli
CH_108540 glutamate 5-kinase; EC 2.7.2.11 from Escherichia coli K12
PFams: AA_kinase, PUA
367 amino acids: PaperBLAST, CDD, Compare to cluster

PROB_YEAST / P32264 Glutamate 5-kinase; GK; Gamma-glutamyl kinase; EC 2.7.2.11 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P32264 glutamate 5-kinase (EC 2.7.2.11) from Saccharomyces cerevisiae
PFams: AA_kinase, PUA
428 amino acids: PaperBLAST, CDD, Compare to cluster

P9WHU9 glutamate 5-kinase (EC 2.7.2.11) from Mycobacterium tuberculosis
PFams: AA_kinase, PUA
376 amino acids: PaperBLAST, CDD, Compare to cluster

Q6E235 glutamate 5-kinase (EC 2.7.2.11) from Bacillus subtilis
PFams: AA_kinase, PUA
370 amino acids: PaperBLAST, CDD, Compare to cluster

A0A1H0J514 Glutamate 5-kinase
344 amino acids: PaperBLAST, CDD, Compare to cluster

BT3719 glutamate 5-kinase (EC 2.7.2.11) from Bacteroides thetaiotaomicron VPI-5482
PFams: AA_kinase, PUA
360 amino acids: PaperBLAST, CDD, Compare to cluster

Echvi_4033 glutamate 5-kinase (EC 2.7.2.11) from Echinicola vietnamensis KMM 6221, DSM 17526
PFams: AA_kinase, PUA
362 amino acids: PaperBLAST, CDD, Compare to cluster

Ga0059261_3512 glutamate 5-kinase (EC 2.7.2.11) from Sphingomonas koreensis DSMZ 15582
PFams: AA_kinase, PUA
367 amino acids: PaperBLAST, CDD, Compare to cluster

CA265_RS20855 glutamate 5-kinase (EC 2.7.2.11) from Pedobacter sp. GW460-11-11-14-LB5
PFams: AA_kinase, PUA
359 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 716-795 amino acids (not heteromeric)

P5CS2_ORYSJ / Q941T1 Delta-1-pyrroline-5-carboxylate synthase 2; OsP5CS2; EC 2.7.2.11; EC 1.2.1.41 from Oryza sativa subsp. japonica (Rice)
Q941T1 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Oryza sativa
PFams: AA_kinase, Aldedh
735 amino acids: PaperBLAST, CDD, Compare to cluster

P5CS_MOUSE / Q9Z110 Delta-1-pyrroline-5-carboxylate synthase; P5CS; Aldehyde dehydrogenase family 18 member A1; EC 2.7.2.11; EC 1.2.1.41 from Mus musculus (Mouse)
Q9Z110 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Mus musculus
PFams: AA_kinase, Aldedh
795 amino acids: PaperBLAST, CDD, Compare to cluster

P5CS1_ORYSJ / O04226 Delta-1-pyrroline-5-carboxylate synthase 1; OsP5CS1; EC 2.7.2.11; EC 1.2.1.41 from Oryza sativa subsp. japonica (Rice)
PFams: AA_kinase, Aldedh
716 amino acids: PaperBLAST, CDD, Compare to cluster

P54886 δ-1-pyrroline-5-carboxylate synthase (EC 1.2.1.41; EC 2.7.2.11) from Homo sapiens
P5CS_HUMAN / P54886 Delta-1-pyrroline-5-carboxylate synthase; P5CS; Aldehyde dehydrogenase family 18 member A1; EC 2.7.2.11; EC 1.2.1.41 from Homo sapiens (Human)
PFams: AA_kinase, Aldedh
795 amino acids: PaperBLAST, CDD, Compare to cluster

P54887 δ1-pyrroline-5-carboxylate synthetase (EC 1.2.1.41; EC 2.7.2.11) from Arabidopsis thaliana
PFams: AA_kinase, Aldedh
717 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 251-263 amino acids (not heteromeric)

CH_121311 glutamate 5-kinase; EC 2.7.2.11 from Campylobacter jejuni
PFams: AA_kinase
251 amino acids: PaperBLAST, CDD, Compare to cluster

G5K_LEIDO / A0A0R6Y3I5 Glutamate 5-kinase; LdG5K; Gamma-glutamyl kinase; EC 2.7.2.11 from Leishmania donovani
A0A0R6Y3I5 glutamate 5-kinase (EC 2.7.2.11) from Leishmania donovani
PFams: AA_kinase
263 amino acids: PaperBLAST, CDD, Compare to cluster