Clustering the characterized proteins for proC (pyrroline-5-carboxylate reductase) in L-proline biosynthesis
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Definition of proC
Fetched 28 sequences
Running BLASTp
Found similarities, at above 30% identity and 75% coverage, for 27 of these sequences
Found 1 clusters of similar sequences. Another 3 sequences are not clustered. Download as table or as draft rules or view by organism
G7KRM5 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Medicago truncatula
PFams: F420_oxidored, P5CR_dimer
274 amino acids: PaperBLAST, CDD, Compare to cluster
F4K884 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Arabidopsis thaliana
PFams: F420_oxidored, NAD_binding_2, P5CR_dimer
223 amino acids: PaperBLAST, CDD, Compare to cluster
O87725 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Acetoanaerobium sticklandii
PFams: Shikimate_DH, F420_oxidored, NAD_binding_2, P5CR_dimer
266 amino acids: PaperBLAST, CDD, Compare to cluster
P32322 pyrroline-5-carboxylate reductase 1 subunit (EC 1.5.1.2) from Homo sapiens
P5CR1_HUMAN / P32322 Pyrroline-5-carboxylate reductase 1, mitochondrial; P5C reductase 1; P5CR 1; EC 1.5.1.2 from Homo sapiens (Human)
P32322 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Homo sapiens
PFams: F420_oxidored, P5CR_dimer
319 amino acids: PaperBLAST, CDD, Compare to cluster
Q4DH60 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Trypanosoma cruzi
PFams: F420_oxidored, P5CR_dimer
269 amino acids: PaperBLAST, CDD, Compare to cluster
Q5NQR9 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Zymomonas mobilis subsp. mobilis
PFams: F420_oxidored, NAD_binding_2, P5CR_dimer
271 amino acids: PaperBLAST, CDD, Compare to cluster
P5CR2_HUMAN / Q96C36 Pyrroline-5-carboxylate reductase 2; P5C reductase 2; P5CR 2; EC 1.5.1.2 from Homo sapiens (Human)
Q96C36 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Homo sapiens
PFams: F420_oxidored, P5CR_dimer
320 amino acids: PaperBLAST, CDD, Compare to cluster
Q97ZT3 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Saccharolobus solfataricus
PFams: F420_oxidored, P5CR_dimer
277 amino acids: PaperBLAST, CDD, Compare to cluster
b0386 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Escherichia coli K-12 substr. MG1655
P0A9L8 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Escherichia coli (strain K12)
P5CR_ECOLI / P0A9L8 Pyrroline-5-carboxylate reductase; P5C reductase; P5CR; PCA reductase; EC 1.5.1.2 from Escherichia coli (strain K12)
MB|P0A9L8 pyrroline-5-carboxylate reductase from Escherichia coli K12
PFams: F420_oxidored, NAD_binding_2, P5CR_dimer
269 amino acids: PaperBLAST, CDD, Compare to cluster
P5CR1_BACSU / P0CI77 Pyrroline-5-carboxylate reductase 1; P5C reductase 1; P5CR 1; PCA reductase 1; EC 1.5.1.2 from Bacillus subtilis (strain 168)
PFams: F420_oxidored, P5CR_dimer
297 amino acids: PaperBLAST, CDD, Compare to cluster
P5CR_PSEAE / P22008 Pyrroline-5-carboxylate reductase; P5C reductase; P5CR; PCA reductase; EC 1.5.1.2 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: F420_oxidored, NAD_binding_2, NAD_Gly3P_dh_N, P5CR_dimer
273 amino acids: PaperBLAST, CDD, Compare to cluster
P5CR_TREPA / P27771 Pyrroline-5-carboxylate reductase; P5C reductase; P5CR; PCA reductase; EC 1.5.1.2 from Treponema pallidum (strain Nichols)
PFams: NAD_binding_2, F420_oxidored, P5CR_dimer
263 amino acids: PaperBLAST, CDD, Compare to cluster
P32263 pyrroline-5-carboxylate reductase subunit (EC 1.5.1.2) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P5CR_YEAST / P32263 Pyrroline-5-carboxylate reductase; P5C reductase; P5CR; EC 1.5.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: F420_oxidored, P5CR_dimer
286 amino acids: PaperBLAST, CDD, Compare to cluster
P5CR2_BACSU / P54552 Pyrroline-5-carboxylate reductase 2; P5C reductase 2; P5CR 2; PCA reductase 2; EC 1.5.1.2 from Bacillus subtilis (strain 168)
PFams: F420_oxidored, P5CR_dimer
278 amino acids: PaperBLAST, CDD, Compare to cluster
P5CR3_HUMAN / Q53H96 Pyrroline-5-carboxylate reductase 3; P5C reductase 3; P5CR 3; Pyrroline-5-carboxylate reductase-like protein; EC 1.5.1.2 from Homo sapiens (Human)
PFams: F420_oxidored, P5CR_dimer
274 amino acids: PaperBLAST, CDD, Compare to cluster
P5CR_KLULA / Q6CR99 Pyrroline-5-carboxylate reductase; P5C reductase; P5CR; EC 1.5.1.2 from Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
PFams: F420_oxidored, P5CR_dimer
285 amino acids: PaperBLAST, CDD, Compare to cluster
P5CR1_MOUSE / Q922W5 Pyrroline-5-carboxylate reductase 1, mitochondrial; P5C reductase 1; P5CR 1; EC 1.5.1.2 from Mus musculus (Mouse)
PFams: F420_oxidored, P5CR_dimer
309 amino acids: PaperBLAST, CDD, Compare to cluster
P5CR_METAC / Q9HH99 Pyrroline-5-carboxylate reductase; P5C reductase; P5CR; PCA reductase; EC 1.5.1.2 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
PFams: F420_oxidored, NAD_binding_2, P5CR_dimer
270 amino acids: PaperBLAST, CDD, Compare to cluster
F2E7Q2 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Hordeum vulgare subsp. vulgare
PFams: F420_oxidored, NAD_binding_2, P5CR_dimer
277 amino acids: PaperBLAST, CDD, Compare to cluster
BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Bacteroides thetaiotaomicron VPI-5482
PFams: F420_oxidored, NAD_binding_2, P5CR_dimer
257 amino acids: PaperBLAST, CDD, Compare to cluster
CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Caulobacter crescentus NA1000
PFams: F420_oxidored, P5CR_dimer
260 amino acids: PaperBLAST, CDD, Compare to cluster
DVU2332 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Desulfovibrio vulgaris Hildenborough JW710
PFams: F420_oxidored, NAD_binding_2, P5CR_dimer
265 amino acids: PaperBLAST, CDD, Compare to cluster
DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Desulfovibrio vulgaris Miyazaki F
PFams: F420_oxidored, NAD_binding_2, P5CR_dimer
269 amino acids: PaperBLAST, CDD, Compare to cluster
Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Shewanella loihica PV-4
PFams: F420_oxidored, NAD_Gly3P_dh_N, P5CR_dimer
272 amino acids: PaperBLAST, CDD, Compare to cluster
CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) from Pedobacter sp. GW460-11-11-14-LB5
PFams: IlvN, F420_oxidored, NAD_binding_2, NAD_Gly3P_dh_N, P5CR_dimer
269 amino acids: PaperBLAST, CDD, Compare to cluster
TR08_CURCL / A0A348AXY1 Pyrroline-5-carboxylate reductase-like protein TR08; KK-1 biosynthesis cluster protein TR08; EC 1.5.1.- (from HMM only) from Curvularia clavata
PFams: F420_oxidored, P5CR_dimer
311 amino acids: PaperBLAST, CDD
(similar to BRENDA::O87725 from Cluster 1, but similarity to seed sequence is below thresholds)
PHQD_PENFE / L0E163 Pyrroline-5-carboxylate reductase; P5C reductase; P5CR; Paraherquamide biosynthesis cluster protein D; EC 1.5.1.2 from Penicillium fellutanum
PFams: F420_oxidored, P5CR_dimer
322 amino acids: PaperBLAST, CDD
(similar to reanno::Caulo:CCNA_00528 from Cluster 1, but similarity to seed sequence is below thresholds)
P5CR3_BACSU / Q00777 Pyrroline-5-carboxylate reductase 3; P5C reductase 3; P5CR 3; PCA reductase 3; EC 1.5.1.2 from Bacillus subtilis (strain 168)
PFams: F420_oxidored, P5CR_dimer
272 amino acids: PaperBLAST, CDD