Clusters of Characterized Proteins

Clustering the characterized proteins for proP (proline:H+ symporter ProP) in L-proline catabolism

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Definition of proP

• Curated sequence CH_024324: proline porter II. Proline/betaine transporter; Proline porter II; PPII. (Proline/glycine-betaine):(H+/Na+) symporter, ProP (also transports taurine, ectoine, pipecolate, proline-betaine, N,N-dimethylglycine, carnitine, and 1-carboxymethyl-pyridinium) (subject to osmotic activation). Transmembrane helix I and periplasmic loop 1 are involved in osmosensing and osmoprotectant transport. osmolyte:H⁺ symporter ProP. osmolyte:H⁺ symporter ProP
• Curated sequence Q47421: Glycine betaine/proline/ectoine/pipecolic acid transporter OusA; Osmoprotectant uptake system A
• Curated sequence Q79VC4: Ectoine/proline transporter ProP

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 3 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 500-504 amino acids (not heteromeric)

b4111 osmolyte:H⁺ symporter ProP from Escherichia coli K-12 substr. MG1655
P0C0L7 osmolyte:H⁺ symporter ProP from Escherichia coli (strain K12)
PROP_ECOLI / P0C0L7 Proline/betaine transporter; Proline porter II; PPII from Escherichia coli (strain K12)
TC 2.A.1.6.4 / P0C0L7 (Proline/glycine-betaine):(H+/Na+) symporter, ProP (also transports taurine, ectoine, pipecolate, proline-betaine, N,N-dimethylglycine, carnitine, and 1-carboxymethyl-pyridinium) (subject to osmotic activation). Transmembrane helix I and periplasmic loop 1 are involved in osmosensing and osmoprotectant transport from Escherichia coli
RF|NP_418535 proline porter II from Escherichia coli K12
PFams: Sugar_tr, MFS_1, MFS_1, Osmo_CC
500 amino acids: PaperBLAST, CDD, Compare to cluster

OUSA_DICD3 / Q47421 Glycine betaine/proline/ectoine/pipecolic acid transporter OusA; Osmoprotectant uptake system A from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
PFams: Sugar_tr, MFS_1, MFS_1, Osmo_CC
501 amino acids: PaperBLAST, CDD, Compare to cluster

PROP_CORGL / Q79VC4 Ectoine/proline transporter ProP from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: Sugar_tr, MFS_1
504 amino acids: PaperBLAST, CDD, Compare to cluster