Clusters of Characterized Proteins

Clustering the characterized proteins for srlB (PTS system for sorbitol SrlABE, EII-A component SrlB) in D-sorbitol (glucitol) catabolism

Or see other characterized proteins similar to srlB

Or see all steps for D-sorbitol (glucitol) catabolism

Or cluster curated proteins matching a keyword

Definition of srlB

• Curated sequence CH_090883: PTS system, glucitol/sorbitol-specific, IIA component. PTS system glucitol/sorbitol-specific EIIA component; EIIA-Gut; EIII-Gut; Glucitol/sorbitol-specific phosphotransferase enzyme IIA component. PTHA aka SRLB aka GUTB aka B2704, component of Glucitol porter. sorbitol-specific PTS enzyme IIA component (EC 2.7.1.198; EC 2.7.1.197). sorbitol-specific PTS enzyme IIA component (EC 2.7.1.198; EC 2.7.1.197)
• Curated sequence O32334: GutB, component of The Glucitol Enzyme II complex, IICBC (GutA1A2) IIA (GutB)
• UniProt sequence O32523: SubName: Full=Sorbitol phosphotransferase enzyme II {ECO:0000313|EMBL:CAA74943.1};
• Comment: A complication in Erwinia -- srlB is present in Erwinia amylovora (O32523_ERWAM, 50% identical) but is not curated, probably because PMID:9435786 do not report a mutant in it. Since it is in a characterized cluster, decided to include it. PMID:9435786 also suggests that EII-BC1 is split into srlA/srlE but I think this is not correct.

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 3 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 122-123 amino acids (2/3 heteromeric)

b2704 sorbitol-specific PTS enzyme IIA component (EC 2.7.1.198; EC 2.7.1.197) from Escherichia coli K-12 substr. MG1655
P05706 sorbitol-specific PTS enzyme IIA component (EC 2.7.1.198; EC 2.7.1.197) from Escherichia coli (strain K12)
PTHA_ECOLI / P05706 PTS system glucitol/sorbitol-specific EIIA component; EIIA-Gut; EIII-Gut; Glucitol/sorbitol-specific phosphotransferase enzyme IIA component from Escherichia coli (strain K12)
TC 4.A.4.1.1 / P05706 PTHA aka SRLB aka GUTB aka B2704, component of Glucitol porter from Escherichia coli
CH_090883 PTS system, glucitol/sorbitol-specific, IIA component from Escherichia coli K12
PFams: PTSIIA_gutA
Heteromeric, 123 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.4.1.2 / O32334 GutB, component of The Glucitol Enzyme II complex, IICBC (GutA1A2) IIA (GutB) from Clostridium beijerinckii
PFams: PTSIIA_gutA
Heteromeric, 122 amino acids: PaperBLAST, CDD, Compare to cluster

O32523 Sorbitol phosphotransferase enzyme II
123 amino acids: PaperBLAST, CDD, Compare to cluster