Clusters of Characterized Proteins

Clustering the characterized proteins for Slc2a5 (fructose:H+ symporter) in sucrose catabolism

Or see other characterized proteins similar to Slc2a5

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Definition of Slc2a5

• Curated sequence A0ZXK6: The monosaccharide (MST) (glucose > mannose > galactose > fructose):H+ symporter, MST1
• Curated sequence CH_091463: sugar transport protein 13. The glucose/fructose:H+ symporter, STP13 (sugar transport protein 13). Expressed in vascular tissues and induced during programmed cell death
• Curated sequence P22732: Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5. Fructose uniporter, GLUT5
• Curated sequence P43427: Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5
• Curated sequence P46408: Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5
• Curated sequence P58353: Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5
• Ignore hits to Q6PXP3 when looking for 'other' hits (Solute carrier family 2, facilitated glucose transporter member 7; Glucose transporter type 7; GLUT-7; hGLUT7. The glucose/fructose facilitator, Glut7 (SLC2A7) (a single mutation, I314V, results in loss of fructose transport but retention of glucose transport)
• Curated sequence Q9WV38: Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5
• Curated sequence Q9XIH7: The fructose/xylose:H+ symporter, PMT1 (polyol monosaccharide transporter-1). Also transports other substrates at lower rates. PMT2 is largely of the same sequence and function. Both are present in pollen and young xylem cells (Klepek et al., 2005). A similar ortholog has been identifed in pollen grains of Petunia hybrida
• Comment: Ignore Q6PXP3 (GTR7_HUMAN) as there is debate as to its activity

Fetched 8 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 8 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 486-540 amino acids (not heteromeric)

TC 2.A.1.1.43 / A0ZXK6 The monosaccharide (MST) (glucose > mannose > galactose > fructose):H+ symporter, MST1 from Geosiphon pyriformis
PFams: Sugar_tr, MFS_1
540 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.1.1.50 / Q94AZ2 The glucose/fructose:H+ symporter, STP13 (sugar transport protein 13). Expressed in vascular tissues and induced during programmed cell death from Arabidopsis thaliana (Mouse-ear cress)
RF|NP_198006.1 sugar transport protein 13 from Arabidopsis thaliana
PFams: Sugar_tr, MFS_1
526 amino acids: PaperBLAST, CDD, Compare to cluster

GTR5_HUMAN / P22732 Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5 from Homo sapiens (Human)
TC 2.A.1.1.13 / P22732 Fructose uniporter, GLUT5
PFams: Sugar_tr, MFS_1
501 amino acids: PaperBLAST, CDD, Compare to cluster

GTR5_RAT / P43427 Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5 from Rattus norvegicus (Rat)
PFams: MFS_1, Sugar_tr
502 amino acids: PaperBLAST, CDD, Compare to cluster

GTR5_RABIT / P46408 Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5 from Oryctolagus cuniculus (Rabbit)
PFams: Sugar_tr, MFS_1
486 amino acids: PaperBLAST, CDD, Compare to cluster

GTR5_BOVIN / P58353 Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5 from Bos taurus (Bovine)
PFams: Sugar_tr, MFS_1
501 amino acids: PaperBLAST, CDD, Compare to cluster

GTR5_MOUSE / Q9WV38 Solute carrier family 2, facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5 from Mus musculus (Mouse)
PFams: Sugar_tr, MFS_1
501 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.1.1.75 / Q9XIH7 The fructose/xylose:H+ symporter, PMT1 (polyol monosaccharide transporter-1). Also transports other substrates at lower rates. PMT2 is largely of the same sequence and function. Both are present in pollen and young xylem cells (Klepek et al., 2005). A similar ortholog has been identifed in pollen grains of Petunia hybrida from Arabidopsis thaliana
PFams: Sugar_tr, MFS_1
511 amino acids: PaperBLAST, CDD, Compare to cluster