Clusters of Characterized Proteins

Clustering the characterized proteins for fruA (fructose-specific PTS system (fructose 1-phosphate forming), EII-B'BC components) in sucrose catabolism

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Definition of fruA

• Curated sequence Q8DWE7: protein-Npi-phosphohistidine-D-fructose phosphotransferase (subunit 2/2) (EC 2.7.1.202). Putative PTS system, fructose-specific IIBC component aka FruC, component of The constitutive fructose porter FruC/FruD
• Curated sequence P20966: PTS system fructose-specific EIIB'BC component; EIIB'BC-Fru; EC 2.7.1.202. PTFB aka FRUA aka PTSF aka B2167, component of Fructose porter (FruAB) (fructose-1-P forming). fructose-specific PTS multiphosphoryl transfer protein FruA. fructose-specific PTS multiphosphoryl transfer protein FruA
• Curated sequence P23355: PTS system fructose-specific EIIB'BC component; EIIB'BC-Fru; EC 2.7.1.202
• Ignore hits to P32154 when looking for 'other' hits (Fructose-like PTS system EIIBC component, component of Fructose-like PTS Enzyme II complex, FrvA (IIA of 148 aas) - FrvB (IIBC of 483 aas and 9 predicted TMSs). putative PTS enzyme IIBC component FrvB)
• Curated sequence Q9HY57: Phosphotransferase system transporter fructose-specific IIBC component, FruA, component of Fructose-specific PTS permease, FruIIBC/FruI-HPr-IIA
• Curated sequence Q9RZP7: Fructose PTS Enzyme IIBC, FruA
• UniProt sequence G8B0J2: SubName: Full=Fructose phosphotransferase system, IIB/IIC components {ECO:0000313|EMBL:CCD03701.1};

Fetched 6 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 6 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 466-598 amino acids (3/6 heteromeric)

Q8DWE7 protein-Npi-phosphohistidine-D-fructose phosphotransferase (subunit 2/2) (EC 2.7.1.202) from Streptococcus mutans serotype c
TC 4.A.2.1.8 / Q8DWE7 Putative PTS system, fructose-specific IIBC component aka FruC, component of The constitutive fructose porter FruC/FruD from Streptococcus mutans
PFams: PTS_IIB, PTS_EIIC
Heteromeric, 466 amino acids: PaperBLAST, CDD, Compare to cluster

b2167 fructose-specific PTS multiphosphoryl transfer protein FruA from Escherichia coli K-12 substr. MG1655
P20966 fructose-specific PTS multiphosphoryl transfer protein FruA from Escherichia coli (strain K12)
PTFBC_ECOLI / P20966 PTS system fructose-specific EIIB'BC component; EIIB'BC-Fru; EC 2.7.1.202 from Escherichia coli (strain K12)
TC 4.A.2.1.1 / P20966 PTFB aka FRUA aka PTSF aka B2167, component of Fructose porter (FruAB) (fructose-1-P forming) from Escherichia coli
PFams: PTS_IIB, PTS_EIIC
Heteromeric, 563 amino acids: PaperBLAST, CDD, Compare to cluster

PTFBC_XANCP / P23355 PTS system fructose-specific EIIB'BC component; EIIB'BC-Fru; EC 2.7.1.202 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
PFams: PTS_IIB
580 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.2.1.17 / Q9HY57 Phosphotransferase system transporter fructose-specific IIBC component, FruA, component of Fructose-specific PTS permease, FruIIBC/FruI-HPr-IIA from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: PTS_IIB, PTS_IIB, PTS_EIIC
Heteromeric, 585 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.2.1.18 / Q9RZP7 Fructose PTS Enzyme IIBC, FruA from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
PFams: PTS_IIB, PTS_IIB
598 amino acids: PaperBLAST, CDD, Compare to cluster

G8B0J2 Fructose phosphotransferase system, IIB/IIC components
580 amino acids: PaperBLAST, CDD, Compare to cluster