Clusters of Characterized Proteins

Clustering the characterized proteins for sacP (sucrose phosphotransferase enzyme EII-BC) in sucrose catabolism

Or see other characterized proteins similar to sacP

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Definition of sacP

• Curated sequence P27219: protein-Npi-phosphohistidine-sucrose phosphotransferase (EC 2.7.1.211). Enzyme II^scr (EC 2.7.1.211)
• Curated sequence P51184: protein-Npi-phosphohistidine-sucrose phosphotransferase (EC 2.7.1.211). Enzyme II^scr (EC 2.7.1.211)
• Curated sequence P15400: Negative regulator of SacY activity; PTS system sac EIIBC component; EC 2.7.1.-. Sucrose porter and regulatory sensor, IIBC (SacX) (43% identical to 4.A.1.2.1) (Tortosa and Le Coq 1995). The IIA domains of PtsA, GamP, PtsG and GmuA can all phosphorylate the IIB domain in the SacX sensor
• Curated sequence P05306: Sucrose porter, IIBC (SacP) (55% identical to 4.A.1.2.1)
• Curated sequence P08470: Sucrose porter (ScrA)
• Comment: This is PTS-II-BC system (TIGR01996). TIGRFam describes it as relying on the glucose II-A protein (crr). But in B. subtilis, many different II-A proteins can phosphorylate the II-B domains (PMID:30038046). So, treat it as a single-component system. Since the II-A component is not specific, describe it as a 1-component system.

Fetched 5 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 5 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 456-480 amino acids (not heteromeric)

P27219 Enzyme II^scr (EC 2.7.1.211) from Klebsiella pneumoniae
P27219 protein-Npi-phosphohistidine-sucrose phosphotransferase (EC 2.7.1.211) from Klebsiella pneumoniae
PFams: PTS_EIIB, PTS_EIIC
456 amino acids: PaperBLAST, CDD, Compare to cluster

P51184 Enzyme II^scr (EC 2.7.1.211) from Staphylococcus xylosus
P51184 protein-Npi-phosphohistidine-sucrose phosphotransferase (EC 2.7.1.211) from Staphylococcus xylosus
PFams: PTS_EIIB, PTS_EIIC
480 amino acids: PaperBLAST, CDD, Compare to cluster

SACX_BACSU / P15400 Negative regulator of SacY activity; PTS system sac EIIBC component; EC 2.7.1.- from Bacillus subtilis (strain 168)
TC 4.A.1.2.10 / P15400 Sucrose porter and regulatory sensor, IIBC (SacX) (43% identical to 4.A.1.2.1) (Tortosa and Le Coq 1995). The IIA domains of PtsA, GamP, PtsG and GmuA can all phosphorylate the IIB domain in the SacX sensor from Bacillus subtilis
PFams: PTS_EIIB, PTS_EIIC
459 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.1.2.9 / P05306 Sucrose porter, IIBC (SacP) (55% identical to 4.A.1.2.1) from Bacillus subtilis
PFams: PTS_EIIB, PTS_EIIC
461 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.1.2.1 / P08470 Sucrose porter (ScrA) from Salmonella typhimurium
PFams: PTS_EIIB, PTS_EIIC
456 amino acids: PaperBLAST, CDD, Compare to cluster