GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for L-LDH (L-lactate dehydrogenase) in L-threonine catabolism

Or see other characterized proteins similar to L-LDH

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Definition of L-LDH

Fetched 55 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 55 of these sequences

Found 3 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 304-334 amino acids (not heteromeric)

LDH_THEMA / P16115 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
PFams: Ldh_1_N, Ldh_1_C
319 amino acids: PaperBLAST, CDD, Compare to cluster

A0A1A6GB48 L-lactate dehydrogenase (EC 1.1.1.27) from Enterococcus mundtii
PFams: Ldh_1_N, Ldh_1_C
324 amino acids: PaperBLAST, CDD, Compare to cluster

B1A4R6 L-lactate dehydrogenase (EC 1.1.1.27) from Thermoanaerobacter ethanolicus
PFams: Ldh_1_N, UDPG_MGDP_dh_N, Ldh_1_C
311 amino acids: PaperBLAST, CDD, Compare to cluster

B7XH73 L-lactate dehydrogenase (EC 1.1.1.27) from Equus caballus
PFams: Ldh_1_N, Ldh_1_C
332 amino acids: PaperBLAST, CDD, Compare to cluster

B9MKZ8 L-lactate dehydrogenase (EC 1.1.1.27) from Caldicellulosiruptor bescii
PFams: Ldh_1_N, Ldh_1_C
314 amino acids: PaperBLAST, CDD, Compare to cluster

E7CXT1 L-lactate dehydrogenase (EC 1.1.1.27) from Thermoanaerobacterium saccharolyticum
PFams: Ldh_1_N, UDPG_MGDP_dh_N, Ldh_1_C
311 amino acids: PaperBLAST, CDD, Compare to cluster

P00336 L-lactate dehydrogenase (EC 1.1.1.27) from Sus scrofa
PFams: Ldh_1_N, Ldh_1_C
334 amino acids: PaperBLAST, CDD, Compare to cluster

LDHA_HUMAN / P00338 L-lactate dehydrogenase A chain; LDH-A; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59; EC 1.1.1.27 from Homo sapiens (Human)
P00338 L-lactate dehydrogenase (EC 1.1.1.27) from Homo sapiens
PFams: Ldh_1_N, Ldh_1_C
332 amino acids: PaperBLAST, CDD, Compare to cluster

LDHA_PIG / P00339 L-lactate dehydrogenase A chain; LDH-A; LDH muscle subunit; LDH-M; EC 1.1.1.27 from Sus scrofa (Pig)
P00339 L-lactate dehydrogenase (EC 1.1.1.27) from Sus scrofa
PFams: Ldh_1_N, Ldh_1_C
332 amino acids: PaperBLAST, CDD, Compare to cluster

P00345 L-lactate dehydrogenase (EC 1.1.1.27) from Bacillus megaterium
PFams: Ldh_1_N, Ldh_1_C
318 amino acids: PaperBLAST, CDD, Compare to cluster

LDHB_HUMAN / P07195 L-lactate dehydrogenase B chain; LDH-B; LDH heart subunit; LDH-H; Renal carcinoma antigen NY-REN-46; EC 1.1.1.27 from Homo sapiens (Human)
P07195 L-lactate dehydrogenase (EC 1.1.1.27) from Homo sapiens
PFams: Ldh_1_N, Ldh_1_C
334 amino acids: PaperBLAST, CDD, Compare to cluster

P07864 L-lactate dehydrogenase (EC 1.1.1.27) from Homo sapiens
PFams: Ldh_1_N, Ldh_1_C
332 amino acids: PaperBLAST, CDD, Compare to cluster

P26283 L-lactate dehydrogenase subunit (EC 1.1.1.27) from Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
P26283 L-lactate dehydrogenase (EC 1.1.1.27) from Streptococcus mutans serotype c
PFams: Ldh_1_N, Ldh_1_C
328 amino acids: PaperBLAST, CDD, Compare to cluster

P90613 L-lactate dehydrogenase (EC 1.1.1.27) from Toxoplasma gondii
PFams: Ldh_1_N, Ldh_1_C
329 amino acids: PaperBLAST, CDD, Compare to cluster

Q0GND8 L-lactate dehydrogenase (EC 1.1.1.27) from Iguana iguana
PFams: Ldh_1_N, Ldh_1_C
332 amino acids: PaperBLAST, CDD, Compare to cluster

Q0GND9 L-lactate dehydrogenase (EC 1.1.1.27) from Amblyrhynchus cristatus
PFams: Ldh_1_N, Ldh_1_C
332 amino acids: PaperBLAST, CDD, Compare to cluster

Q27743 L-lactate dehydrogenase (EC 1.1.1.27) from Plasmodium falciparum
CH_023953 lactate dehydrogenase; EC 1.1.1.27 from Plasmodium falciparum
GB|ABA46354.1 lactate dehydrogenase; EC 1.1.1.27 from Plasmodium falciparum
PFams: Ldh_1_N, Ldh_1_C
316 amino acids: PaperBLAST, CDD, Compare to cluster

Q27797 L-lactate dehydrogenase (EC 1.1.1.27) from Toxoplasma gondii
PFams: Ldh_1_N, Ldh_1_C
326 amino acids: PaperBLAST, CDD, Compare to cluster

Q8I8U3 L-lactate dehydrogenase (EC 1.1.1.27) from Eimeria maxima
PFams: Ldh_1_N, Glyco_hydro_4, Ldh_1_C
330 amino acids: PaperBLAST, CDD, Compare to cluster

Q8I8U4 L-lactate dehydrogenase (EC 1.1.1.27) from Eimeria tenella
PFams: Ldh_1_N, Ldh_1_C
331 amino acids: PaperBLAST, CDD, Compare to cluster

Q8I8U5 L-lactate dehydrogenase (EC 1.1.1.27) from Eimeria acervulina
PFams: Ldh_1_N, Ldh_1_C
330 amino acids: PaperBLAST, CDD, Compare to cluster

Q9GT92 L-lactate dehydrogenase (EC 1.1.1.27) from Cryptosporidium parvum
PFams: Ldh_1_N, Ldh_1_C
321 amino acids: PaperBLAST, CDD, Compare to cluster

W8CXQ9 L-lactate dehydrogenase (EC 1.1.1.27) from Bacillus coagulans
PFams: Ldh_1_N, Ldh_1_C
312 amino acids: PaperBLAST, CDD, Compare to cluster

Q7Z0X7 L-lactate dehydrogenase (EC 1.1.1.27) from Babesia bovis
CH_024078 L-lactate dehydrogenase; EC 1.1.1.27 from Babesia bovis T2Bo
PFams: Ldh_1_N, Ldh_1_C
330 amino acids: PaperBLAST, CDD, Compare to cluster

CH_090731 L-lactate dehydrogenase 1; EC 1.1.1.27 from Lactobacillus plantarum
PFams: Ldh_1_N, Ldh_1_C
320 amino acids: PaperBLAST, CDD, Compare to cluster

CH_090734 L-lactate dehydrogenase 1; EC 1.1.1.27 from Lactococcus lactis subsp. lactis
PFams: Ldh_1_N, Ldh_1_C
325 amino acids: PaperBLAST, CDD, Compare to cluster

LDH1_STAAE / A6QDL6 L-lactate dehydrogenase 1; L-LDH 1; EC 1.1.1.27 from Staphylococcus aureus (strain Newman)
LDH1_STAAC / Q5HJD7 L-lactate dehydrogenase 1; L-LDH 1; EC 1.1.1.27 from Staphylococcus aureus (strain COL)
PFams: Ldh_1_N, Ldh_1_C
317 amino acids: PaperBLAST, CDD, Compare to cluster

LDH2_STAAE / A6QK89 L-lactate dehydrogenase 2; L-LDH 2; EC 1.1.1.27 from Staphylococcus aureus (strain Newman)
LDH2_STAAC / Q5HCV0 L-lactate dehydrogenase 2; L-LDH 2; EC 1.1.1.27 from Staphylococcus aureus (strain COL)
PFams: Ldh_1_N, Ldh_1_C
319 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_LACLN / D8KFT1 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Lactococcus lactis subsp. cremoris (strain NZ9000)
PFams: Ldh_1_N, Ldh_1_C
314 amino acids: PaperBLAST, CDD, Compare to cluster

E8ME30 L-lactate dehydrogenase subunit (EC 1.1.1.27) from Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b)
LDH2_BIFL2 / E8ME30 L-lactate dehydrogenase 2; L-LDH 2; FBP-dependent LDH; EC 1.1.1.27 from Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b)
PFams: Ldh_1_N, Ldh_1_C
320 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_LACHE / O32765 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Lactobacillus helveticus (Lactobacillus suntoryeus)
PFams: Ldh_1_N, Ldh_1_C
323 amino acids: PaperBLAST, CDD, Compare to cluster

LDHA_SQUAC / P00341 L-lactate dehydrogenase A chain; LDH-A; LDH-M; EC 1.1.1.27 from Squalus acanthias (Spiny dogfish)
PFams: Ldh_1_N, Ldh_1_C
333 amino acids: PaperBLAST, CDD, Compare to cluster

LDHC_MOUSE / P00342 L-lactate dehydrogenase C chain; LDH-C; LDH testis subunit; LDH-X; EC 1.1.1.27 from Mus musculus (Mouse)
PFams: Ldh_1_N, Ldh_1_C
332 amino acids: PaperBLAST, CDD, Compare to cluster

P00343 L-lactate dehydrogenase subunit (EC 1.1.1.27) from Lactobacillus casei
LDH_LACCA / P00343 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Lactobacillus casei
PFams: Ldh_1_N, Ldh_1_C
326 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_GEOSE / P00344 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Geobacillus stearothermophilus (Bacillus stearothermophilus)
P00344 L-lactate dehydrogenase (EC 1.1.1.27) from Geobacillus stearothermophilus
PFams: Ldh_1_N, Ldh_1_C
317 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_THECA / P06150 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Thermus caldophilus
PFams: Ldh_1_N, Ldh_1_C
310 amino acids: PaperBLAST, CDD, Compare to cluster

LDHA_MOUSE / P06151 L-lactate dehydrogenase A chain; LDH-A; LDH muscle subunit; LDH-M; EC 1.1.1.27 from Mus musculus (Mouse)
PFams: Ldh_1_N, Ldh_1_C
332 amino acids: PaperBLAST, CDD, Compare to cluster

LDHA_RABIT / P13491 L-lactate dehydrogenase A chain; LDH-A; LDH muscle subunit; LDH-M; EC 1.1.1.27 from Oryctolagus cuniculus (Rabbit)
PFams: Ldh_1_N, Ldh_1_C
332 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_BACSU / P13714 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Bacillus subtilis (strain 168)
PFams: Ldh_1_N, Ldh_1_C
320 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_THEAQ / P13715 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Thermus aquaticus
PFams: Ldh_1_N, Ldh_1_C
310 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_DEIRA / P50933 L-lactate dehydrogenase; L-LDH; 2-ketoacid:NAD-dependent dehydrogenase; EC 1.1.1.27 from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
PFams: Ldh_1_N, Ldh_1_C
304 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_LACPE / P56511 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Lactobacillus pentosus
CH_090729 L-lactate dehydrogenase; EC 1.1.1.27 from Lactobacillus pentosus
PFams: Ldh_1_N, Ldh_1_C
320 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_PEDAC / Q59645 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Pediococcus acidilactici
PFams: Ldh_1_N, Ldh_1_C
323 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_THET8 / Q5SJA1 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
PFams: Ldh_1_N, Ldh_1_C
310 amino acids: PaperBLAST, CDD, Compare to cluster

LDH6A_HUMAN / Q6ZMR3 L-lactate dehydrogenase A-like 6A; EC 1.1.1.27 from Homo sapiens (Human)
PFams: Ldh_1_N, Ldh_1_C
332 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_PLABA / Q7SI97 L-lactate dehydrogenase; EC 1.1.1.27 from Plasmodium berghei (strain Anka)
PFams: Ldh_1_N, Ldh_1_C
316 amino acids: PaperBLAST, CDD, Compare to cluster

LDH_SELRU / Q9EVR0 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Selenomonas ruminantium
PFams: Ldh_1_N, Ldh_1_C
318 amino acids: PaperBLAST, CDD, Compare to cluster

P04642 lactate dehydrogenase subunit (EC 1.1.1.27) from Rattus norvegicus
PFams: Ldh_1_N, Ldh_1_C
332 amino acids: PaperBLAST, CDD, Compare to cluster

P78007 L-lactate dehydrogenase (EC 1.1.1.27) from Mycoplasma pneumoniae (strain ATCC 29342 / M129)
PFams: Ldh_1_N, Ldh_1_C
312 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 376-396 amino acids (not heteromeric)

b3605 L-lactate dehydrogenase from Escherichia coli K-12 substr. MG1655
P33232 L-lactate dehydrogenase from Escherichia coli (strain K12)
LLDD_ECOLI / P33232 L-lactate dehydrogenase; EC 1.1.-.- from Escherichia coli (strain K12)
CH_000618 L-lactate dehydrogenase [cytochrome]; EC 1.1.2.3 from Escherichia coli K12
PFams: FMN_dh
396 amino acids: PaperBLAST, CDD, Compare to cluster

SM_b20850 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) from Sinorhizobium meliloti 1021
PFams: FMN_dh, NMO, Glu_synthase
378 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_19130 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) from Pseudomonas simiae WCS417
PFams: FMN_dh
376 amino acids: PaperBLAST, CDD, Compare to cluster

Ac3H11_1623 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) from Acidovorax sp. GW101-3H11
PFams: FMN_dh, NMO
390 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 558-591 amino acids (not heteromeric)

P00175 L-lactate dehydrogenase subunit (EC 1.1.2.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYB2_YEAST / P00175 Cytochrome b2, mitochondrial; L-lactate dehydrogenase [Cytochrome]; L-lactate ferricytochrome C oxidoreductase; L-LCR; EC 1.1.2.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P00175 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) from Saccharomyces cerevisiae
PFams: Cyt-b5, FMN_dh, Glu_synthase
591 amino acids: PaperBLAST, CDD, Compare to cluster

W1QKE8 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) from Ogataea angusta
PFams: Cyt-b5, FMN_dh, Glu_synthase
558 amino acids: PaperBLAST, CDD, Compare to cluster