Clusters of Characterized Proteins

Clustering the characterized proteins for braC (L-alanine/L-serine/L-threonine ABC transporter, substrate binding protein (BraC/NatB)) in L-threonine catabolism

Or see other characterized proteins similar to braC

Or see all steps for L-threonine catabolism

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Definition of braC

• Curated sequence P21175: Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein; LIVAT-BP; Leu/Ile/Val/Thr/Ala-binding protein. Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein, component of Branched chain amino acid uptake transporter. Transports alanine
• Curated sequence Q55387: NatB aka SLR0559, component of Leucine/proline/alanine/serine/glycine (and possibly histidine) porter, NatABCDE
• Curated sequence Q8YVY4: NatB, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB)
• Comment: braC and natB are quite distantly related and were not clustered, but both are SBP

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 441-454 amino acids (heteromeric)

TC 3.A.1.4.2 / Q55387 NatB aka SLR0559, component of Leucine/proline/alanine/serine/glycine (and possibly histidine) porter, NatABCDE
PFams: Peripla_BP_6, Peripla_BP_5, ANF_receptor
Heteromeric, 454 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.4.6 / Q8YVY4 NatB, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB)
PFams: Peripla_BP_5, Peripla_BP_6, ANF_receptor
Heteromeric, 441 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (1/1 heteromeric)

BRAC_PSEAE / P21175 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein; LIVAT-BP; Leu/Ile/Val/Thr/Ala-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
TC 3.A.1.4.8 / P21175 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: Peripla_BP_6, Peripla_BP_5, ANF_receptor
Heteromeric, 373 amino acids: PaperBLAST, CDD