Clusters of Characterized Proteins

Clustering the characterized proteins for braF (L-alanine/L-serine/L-threonine ABC transporter, ATP-binding component 1 (BraF/NatA)) in L-threonine catabolism

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Definition of braF

• Curated sequence P21629: High-affinity branched-chain amino acid transport ATP-binding protein BraF, component of Branched chain amino acid uptake transporter. Transports alanine
• Curated sequence Q55164: NatA aka BRAF aka SLR0467, component of Leucine/proline/alanine/serine/glycine (and possibly histidine) porter, NatABCDE
• Curated sequence Q7A2H0: NatA, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB)

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 3 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 255-267 amino acids (heteromeric)

TC 3.A.1.4.8 / P21629 High-affinity branched-chain amino acid transport ATP-binding protein BraF, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: ABC_tran, BCA_ABC_TP_C
Heteromeric, 255 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.4.2 / Q55164 NatA aka BRAF aka SLR0467, component of Leucine/proline/alanine/serine/glycine (and possibly histidine) porter, NatABCDE
PFams: ABC_tran, BCA_ABC_TP_C
Heteromeric, 267 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.4.6 / Q7A2H0 NatA, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB)
PFams: ABC_tran, BCA_ABC_TP_C
Heteromeric, 260 amino acids: PaperBLAST, CDD, Compare to cluster