GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for gcvH (glycine cleavage system, H component (lipoyl protein)) in L-threonine catabolism

Or see other characterized proteins similar to gcvH

Or see all steps for L-threonine catabolism

Or cluster curated proteins matching a keyword

Definition of gcvH

Fetched 16 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 16 of these sequences

Found 3 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 126-170 amino acids (not heteromeric)

O82179 glycine decarboxylase H protein from Arabidopsis thaliana
PFams: GCV_H
156 amino acids: PaperBLAST, CDD, Compare to cluster

P25855 glycine decarboxylase H protein from Arabidopsis thaliana
GCSH1_ARATH / P25855 Glycine cleavage system H protein 1, mitochondrial from Arabidopsis thaliana (Mouse-ear cress)
P25855 glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) from Arabidopsis thaliana
PFams: GCV_H
165 amino acids: PaperBLAST, CDD, Compare to cluster

GCSH_ORYSJ / A3C6G9 Glycine cleavage system H protein, mitochondrial from Oryza sativa subsp. japonica (Rice)
PFams: GCV_H
164 amino acids: PaperBLAST, CDD, Compare to cluster

GCSH_BACSU / O32174 Glycine cleavage system H protein; Octanoyl/lipoyl carrier protein from Bacillus subtilis (strain 168)
PFams: GCV_H
127 amino acids: PaperBLAST, CDD, Compare to cluster

b2904 glycine cleavage system H protein from Escherichia coli K-12 substr. MG1655
P0A6T9 glycine cleavage system H protein from Escherichia coli (strain K12)
GCSH_ECOLI / P0A6T9 Glycine cleavage system H protein from Escherichia coli (strain K12)
PFams: GCV_H
129 amino acids: PaperBLAST, CDD, Compare to cluster

P11183 H-protein-(lipoyl)lysine from Gallus gallus
GCSH_CHICK / P11183 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Gallus gallus (Chicken)
PFams: GCV_H
164 amino acids: PaperBLAST, CDD, Compare to cluster

GCSH_YEAST / P39726 Glycine cleavage system H protein, mitochondrial; Glycine decarboxylase complex subunit H from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: GCV_H
170 amino acids: PaperBLAST, CDD, Compare to cluster

GCSH_FLATR / P46485 Glycine cleavage system H protein, mitochondrial; Lipoyl-bearing H protein from Flaveria trinervia (Clustered yellowtops) (Oedera trinervia)
PFams: GCV_H
165 amino acids: PaperBLAST, CDD, Compare to cluster

GCSH_STAAM / P64213 Glycine cleavage system H protein; Octanoyl/lipoyl carrier protein from Staphylococcus aureus (strain Mu50 / ATCC 700699)
PFams: GCV_H
126 amino acids: PaperBLAST, CDD, Compare to cluster

GCSH_THET8 / Q5SKW9 Glycine cleavage system H protein from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
PFams: GCV_H, Biotin_lipoyl
128 amino acids: PaperBLAST, CDD, Compare to cluster

GCSH3_ARATH / Q9LQL0 Glycine cleavage system H protein 3, mitochondrial from Arabidopsis thaliana (Mouse-ear cress)
PFams: GCV_H
166 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 173-173 amino acids (not heteromeric)

P23434 glycine cleavage system H protein, mitochondrial from Homo sapiens
GCSH_HUMAN / P23434 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Homo sapiens (Human)
P23434 glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) from Homo sapiens
PFams: GCV_H
173 amino acids: PaperBLAST, CDD, Compare to cluster

GCSH_BOVIN / P20821 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Bos taurus (Bovine)
PFams: GCV_H
173 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 110-110 amino acids (not heteromeric)

GCVHL_STRPG / P0DN69 Glycine cleavage system H-like protein; GcvH-L from Streptococcus pyogenes serotype M5 (strain Manfredo)
PFams: GCV_H
110 amino acids: PaperBLAST, CDD, Compare to cluster

GCVHL_STAAM / A0A0H3JT43 Glycine cleavage system H-like protein; GcvH-L from Staphylococcus aureus (strain Mu50 / ATCC 700699)
PFams: GCV_H
110 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

GCSH_SCHPO / Q9HDV9 Putative glycine cleavage system H protein, mitochondrial; Glycine decarboxylase complex subunit H from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: GCV_H
169 amino acids: PaperBLAST, CDD
(similar to SwissProt::A3C6G9 from Cluster 1, but similarity to seed sequence is below thresholds)