GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for gloA (glyoxylase I) in L-threonine catabolism

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Definition of gloA

Fetched 26 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 22 of these sequences

Found 2 clusters of similar sequences. Another 4 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 128-185 amino acids (not heteromeric)

O04885 lactoylglutathione lyase (EC 4.4.1.5) from Brassica juncea
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase_6
185 amino acids: PaperBLAST, CDD, Compare to cluster

P0A0T3 lactoylglutathione lyase (EC 4.4.1.5) from Neisseria meningitidis
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase_6
138 amino acids: PaperBLAST, CDD, Compare to cluster

b1651 glyoxalase I (EC 4.4.1.5) from Escherichia coli K-12 substr. MG1655
P0AC81 glyoxalase I (EC 4.4.1.5) from Escherichia coli (strain K12)
LGUL_ECOLI / P0AC81 Lactoylglutathione lyase; Aldoketomutase; Glyoxalase I; Glx I; Ketone-aldehyde mutase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase; EC 4.4.1.5 from Escherichia coli (strain K12)
P0AC81 lactoylglutathione lyase (EC 4.4.1.5) from Escherichia coli
RF|NP_416168.1 lactoylglutathione lyase; EC 4.4.1.5 from Shigella flexneri
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase_6
135 amino acids: PaperBLAST, CDD, Compare to cluster

LGUL_HUMAN / Q04760 Lactoylglutathione lyase; Aldoketomutase; Glyoxalase I; Glx I; Ketone-aldehyde mutase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase; EC 4.4.1.5 from Homo sapiens (Human)
Q04760 lactoylglutathione lyase (EC 4.4.1.5) from Homo sapiens
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase_6
184 amino acids: PaperBLAST, CDD, Compare to cluster

Q2PYM9 lactoylglutathione lyase (EC 4.4.1.5) from Leishmania infantum
PFams: Glyoxalase, Glyoxalase_4
141 amino acids: PaperBLAST, CDD, Compare to cluster

Q5XQR1 lactoylglutathione lyase (EC 4.4.1.5) from Leishmania donovani
PFams: Glyoxalase, Glyoxalase_4
141 amino acids: PaperBLAST, CDD, Compare to cluster

Q68RJ8 lactoylglutathione lyase (EC 4.4.1.5) from Leishmania major
PFams: Glyoxalase, Glyoxalase_4
141 amino acids: PaperBLAST, CDD, Compare to cluster

Q88GF8 lactoylglutathione lyase (EC 4.4.1.5) from Pseudomonas putida
PFams: Glyoxalase, Glyoxalase_4
175 amino acids: PaperBLAST, CDD, Compare to cluster

LGUL_MOUSE / Q9CPU0 Lactoylglutathione lyase; Aldoketomutase; Glyoxalase I; Glx I; Ketone-aldehyde mutase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase; EC 4.4.1.5 from Mus musculus (Mouse)
Q9CPU0 lactoylglutathione lyase (EC 4.4.1.5) from Mus musculus
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase_6
184 amino acids: PaperBLAST, CDD, Compare to cluster

Q9HU72 lactoylglutathione lyase (EC 4.4.1.5) from Pseudomonas aeruginosa
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase_6
176 amino acids: PaperBLAST, CDD, Compare to cluster

Q9HY85 lactoylglutathione lyase (EC 4.4.1.5) from Pseudomonas aeruginosa
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase_6
128 amino acids: PaperBLAST, CDD, Compare to cluster

Q9I5L8 lactoylglutathione lyase (EC 4.4.1.5) from Pseudomonas aeruginosa
PFams: Glyoxalase, Glyoxalase_6, Glyoxalase_4
131 amino acids: PaperBLAST, CDD, Compare to cluster

LGUL_SOYBN / Q9ZS21 Lactoylglutathione lyase; Aldoketomutase; Glyoxalase I; GmGlyoxI; Ketone-aldehyde mutase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase; EC 4.4.1.5 from Glycine max (Soybean) (Glycine hispida)
Q9ZS21 lactoylglutathione lyase (EC 4.4.1.5) from Glycine max
PFams: Glyoxalase, Glyoxalase_4
185 amino acids: PaperBLAST, CDD, Compare to cluster

P16635 glyoxalase I monomer (EC 4.4.1.5) from Pseudomonas putida
PFams: Glyoxalase, Glyoxalase_4
173 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 283-356 amino acids (not heteromeric)

P50107 glyoxalase I (EC 4.4.1.5) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
LGUL_YEAST / P50107 Lactoylglutathione lyase; Aldoketomutase; Glyoxalase I; Glx I; Ketone-aldehyde mutase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase; EC 4.4.1.5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase
326 amino acids: PaperBLAST, CDD, Compare to cluster

D6QLX5 lactoylglutathione lyase (EC 4.4.1.5) from Starmerella magnoliae
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase
315 amino acids: PaperBLAST, CDD, Compare to cluster

Q696X2 lactoylglutathione lyase (EC 4.4.1.5) from Parastagonospora nodorum
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase
321 amino acids: PaperBLAST, CDD, Compare to cluster

Q71KM3 lactoylglutathione lyase (EC 4.4.1.5) from Plasmodium falciparum
PFams: Glyoxalase, Glyoxalase
356 amino acids: PaperBLAST, CDD, Compare to cluster

LGUL_ORYSJ / Q948T6 Lactoylglutathione lyase; Aldoketomutase; Allergen Glb33; Glyoxalase I; Glx I; Glyoxylase I 11; OsGLYI-11; OsGLYI11; Ketone-aldehyde mutase; Methylglyoxalase; PP33; S-D-lactoylglutathione methylglyoxal lyase; Allergen Ory s Glyoxalase I; EC 4.4.1.5 from Oryza sativa subsp. japonica (Rice)
Q948T6 lactoylglutathione lyase (EC 4.4.1.5) from Oryza sativa Japonica Group
PFams: Glyoxalase, Glyoxalase
291 amino acids: PaperBLAST, CDD, Compare to cluster

LGUL_SCHPO / Q09751 Lactoylglutathione lyase; Aldoketomutase; Glyoxalase I; Glx I; Ketone-aldehyde mutase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase; EC 4.4.1.5 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
RF|NP_596010.1 glyoxalase I; EC 4.4.1.5 from Schizosaccharomyces pombe
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase_4, Glyoxalase
302 amino acids: PaperBLAST, CDD, Compare to cluster

GLX1_ARATH / O65398 Lactoylglutathione lyase GLX1; Glyoxalase I; AtGLX1; GlyI; EC 4.4.1.5 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase_6, Glyoxalase
283 amino acids: PaperBLAST, CDD, Compare to cluster

LGUC_ARATH / Q8W593 Probable lactoylglutathione lyase, chloroplastic; Glyoxalase I; EC 4.4.1.5 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Glyoxalase, Glyoxalase_4, Glyoxalase_6, Glyoxalase
350 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/4 heteromeric)

VIR17_SALTY / Q8ZM36 Virulence protein STM3117 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q8ZM36 lactoylglutathione lyase (EC 4.4.1.5) from Salmonella enterica subsp. enterica serovar Typhimurium
PFams: Glyoxalase
144 amino acids: PaperBLAST, CDD

Q97H22 lactoylglutathione lyase (EC 4.4.1.5) from Clostridium acetobutylicum
PFams: Glyoxalase_4
128 amino acids: PaperBLAST, CDD

Q9CJC0 lactoylglutathione lyase (EC 4.4.1.5) from Lactococcus lactis
PFams: Glyoxalase, Glyoxalase
389 amino acids: PaperBLAST, CDD

DJ1D_ARATH / Q9M8R4 Protein DJ-1 homolog D; AtDJ1D; Lactoylglutathione lyase DJ1D; EC 4.4.1.5 from Arabidopsis thaliana (Mouse-ear cress)
PFams: DJ-1_PfpI, DJ-1_PfpI
388 amino acids: PaperBLAST, CDD