Clusters of Characterized Proteins

Clustering the characterized proteins for serP1 (L-threonine uptake transporter SerP1) in L-threonine catabolism

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Definition of serP1

• Curated sequence F2HQ25: Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM)
• Ignore hits to A2RI87 when looking for 'other' hits (Serine permease SerP1)
• Comment: A closely related protein (A2RI87) is annotated as a serine permease only

Fetched 1 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 0 of these sequences

Found 0 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Singletons (0/1 heteromeric)

TC 2.A.3.1.21 / F2HQ25 Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM) from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease, AA_permease_2
459 amino acids: PaperBLAST, CDD