Clusters of Characterized Proteins

Clustering the characterized proteins for aglE (trehalose ABC transporter, substrate-binding component AglE) in trehalose catabolism

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Definition of aglE

• Curated sequence Q9Z3R5: AglE aka R00695 aka SMC03061, component of Sucrose/maltose/trehalose porter (sucrose-inducible). ABC transporter for D-Maltose and D-Trehalose, ATPase component
• UniProt sequence A8LLL6: SubName: Full=Putative bacterial solute-binding protein 1 family {ECO:0000313|EMBL:ABV93394.1};
• Ignore hits to Q55471 when looking for 'other' hits (Slr0529 protein, component of The glucosylglycerol uptake transporter (functions in osmoprotection and also transports sucrose and trehalose (Mikkat and Hagemann, 2000) (most similar to 3.A.1.1.8))
• Comment: S. meliloti aglEFGK. A similar system from Dinoroseobacter shibae, Dshi_1652:Dshi_1648, is involved in maltose uptake. Dinoroseobacter shibae aglE = Dshi_1652 = A8LLL6. Ignore similarity to Slr0529, which may also transport trehalose

Fetched 2 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 452-458 amino acids (1/2 heteromeric)

SMc03061 ABC transporter for D-Maltose and D-Trehalose, ATPase component from Sinorhizobium meliloti 1021
TC 3.A.1.1.8 / Q9Z3R5 AglE aka R00695 aka SMC03061, component of Sucrose/maltose/trehalose porter (sucrose-inducible) from Rhizobium meliloti (Sinorhizobium meliloti)
PFams: SBP_bac_1
Heteromeric, 458 amino acids: PaperBLAST, CDD, Compare to cluster

A8LLL6 Putative bacterial solute-binding protein 1 family
452 amino acids: PaperBLAST, CDD, Compare to cluster