Clusters of Characterized Proteins

Clustering the characterized proteins for crr (glucose PTS, enzyme IIA) in trehalose catabolism

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Definition of crr

• Curated sequence CH_088352: glucose-specific phosphotransferase enzyme IIA component; EC 2.7.1.-. PTS system glucose-specific EIIA component; EIIA-Glc; EIII-Glc; Glucose-specific phosphotransferase enzyme IIA component. Glucose-specific phosphotransferase enzyme IIA component PTGA aka CRR aka GSR aka IEX aka TGS aka TRED aka B2417, component of Glucose porter (PtsG; GlcA; Umg) (transports D-glucose and α-methyl-D-glucopyranoside). Enzyme IIA^Glc (EC 2.7.1.199; EC 2.7.1.201; EC 2.7.1.192). Enzyme IIA^Glc (EC 2.7.1.199)
• Curated sequence P0A283: PTS system glucose-specific EIIA component; EIIA-Glc; EIII-Glc; Glucose-specific phosphotransferase enzyme IIA component
• Ignore hits to Q8L3C4 when looking for 'other' hits (IIA aka Crr, component of The N,N' -diacetylchitobiose Enzyme II (Toratani et al., 2008) (>80% identical to the E. coli enzyme (4.A.3.2.1)))
• Comment: Ignore a close homlog in Serratia (TC 4.A.3.2.5 / Q8L3C4) which is reported to be the II-A component for N,N' -diacetylchitobiose (probably shared with other sugars).

Fetched 2 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 169-169 amino acids (heteromeric)

b2417 Enzyme IIA^Glc (EC 2.7.1.199; EC 2.7.1.201; EC 2.7.1.192) from Escherichia coli K-12 substr. MG1655
P69783 Enzyme IIA^Glc (EC 2.7.1.199) from Escherichia coli (strain K12)
PTGA_ECOLI / P69783 PTS system glucose-specific EIIA component; EIIA-Glc; EIII-Glc; Glucose-specific phosphotransferase enzyme IIA component from Escherichia coli (strain K12)
TC 4.A.1.1.1 / P69783 Glucose-specific phosphotransferase enzyme IIA component PTGA aka CRR aka GSR aka IEX aka TGS aka TRED aka B2417, component of Glucose porter (PtsG; GlcA; Umg) (transports D-glucose and α-methyl-D-glucopyranoside) from Escherichia coli
GB|AAC75470.1 glucose-specific phosphotransferase enzyme IIA component; EC 2.7.1.- from Escherichia coli K12
PFams: PTS_EIIA_1
Heteromeric, 169 amino acids: PaperBLAST, CDD, Compare to cluster

PTGA_SALTY / P0A283 PTS system glucose-specific EIIA component; EIIA-Glc; EIII-Glc; Glucose-specific phosphotransferase enzyme IIA component from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: PTS_EIIA_1
Heteromeric, 169 amino acids: PaperBLAST, CDD, Compare to cluster