Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for glk (glucokinase) in trehalose catabolism

Or see other characterized proteins similar to glk

Or see all steps for trehalose catabolism

Or cluster curated proteins matching a keyword

Definition of glk

Curated proteins or TIGRFams with EC 2.7.1.1
Curated proteins or TIGRFams with EC 2.7.1.2
UniProt sequence A8LLL9: SubName: Full=Glucokinase {ECO:0000313|EMBL:ABV93397.1}; EC=2.7.1.2 {ECO:0000313|EMBL:ABV93397.1};
UniProt sequence Q5GAN8: SubName: Full=General specificity hexokinase {ECO:0000313|EMBL:AAT74901.1};
Curated sequence MONOMER-19002: N-acetylglucosamine kinase (EC 2.7.1.59)
Ignore hits to CH_123431 when looking for 'other' hits (N-acetylglucosamine kinase)
Ignore hits to Q9ADE8 when looking for 'other' hits (polyphosphate-glucose phosphotransferase (EC 2.7.1.63))
UniProt sequence I7DXX1: SubName: Full=Glucokinase Glk {ECO:0000313|EMBL:AFO90274.1}; EC=2.7.1.2 {ECO:0000313|EMBL:AFO90274.1};
Comment: Dshi_1655 (A8LLL9) was identified using fitness data, is very important for growth on glucose and several glucose-containing disaccharides; and functional residues seem to be conserved. The related protein PGA1_c05420 (I7DXX1) also seems to be glk. Q5GAN8 = hexA from B. fragilis is a broad-specificity hexokinase (PMID:15659667). Q5GBH5 = rokA = MONOMER-19002 from B. fragilis is a glucose/mannose/NAG kinase (PMID:15659667). (MetaCyc lists it as NAG kinase only but it is just as active on glucose.) CH_123431 is nearly identical to a characterized broad-specificity hexose kinase, so ignore. SCO5059 (Q9ADE8) is reported to have ATP-glucokinase activity (PMID:24200789), so ignore.

Fetched 98 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 91 of these sequences

Found 4 clusters of similar sequences. Another 8 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 445-572 amino acids (not heteromeric)

A9SJG4 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
522 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0P0I1H5 hexokinase (EC 2.7.1.1) from Helicoverpa armigera
PFams: Hexokinase_1, Hexokinase_2
450 amino acids: PaperBLAST, CDD, Compare to cluster

A0A172WCE4 hexokinase (EC 2.7.1.1) from Eimeria tenella
PFams: Hexokinase_1, Hexokinase_2
468 amino acids: PaperBLAST, CDD, Compare to cluster

A1Z0M6 glucokinase (EC 2.7.1.2) from Botrytis cinerea
PFams: Hexokinase_1, Hexokinase_2
559 amino acids: PaperBLAST, CDD, Compare to cluster

A1Z0M7 hexokinase (EC 2.7.1.1) from Botrytis cinerea
PFams: Hexokinase_1, Hexokinase_2
491 amino acids: PaperBLAST, CDD, Compare to cluster

A3EYB3 glucokinase (EC 2.7.1.2) from Felis catus
PFams: Hexokinase_1, Hexokinase_2
465 amino acids: PaperBLAST, CDD, Compare to cluster

A9RIW3 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
521 amino acids: PaperBLAST, CDD, Compare to cluster

A9S3H4 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
489 amino acids: PaperBLAST, CDD, Compare to cluster

A9S9F8 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
522 amino acids: PaperBLAST, CDD, Compare to cluster

A9SV13 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
520 amino acids: PaperBLAST, CDD, Compare to cluster

A9TDS4 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
518 amino acids: PaperBLAST, CDD, Compare to cluster

A9TLJ2 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
517 amino acids: PaperBLAST, CDD, Compare to cluster

A9U0F4 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
517 amino acids: PaperBLAST, CDD, Compare to cluster

A9U189 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
521 amino acids: PaperBLAST, CDD, Compare to cluster

B8K2W7 hexokinase (EC 2.7.1.1) from Helianthus annuus
PFams: Hexokinase_1, Hexokinase_2
498 amino acids: PaperBLAST, CDD, Compare to cluster

O74996 hexokinase (EC 2.7.1.1) from Yarrowia lipolytica
PFams: Hexokinase_1, Hexokinase_2
534 amino acids: PaperBLAST, CDD, Compare to cluster

HXKA_YEAST / P04806 Hexokinase-1; Hexokinase PI; Hexokinase-A; EC 2.7.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P04806 hexokinase (EC 2.7.1.1) from Saccharomyces cerevisiae
PFams: Hexokinase_1, Hexokinase_2
485 amino acids: PaperBLAST, CDD, Compare to cluster

HXKB_YEAST / P04807 Hexokinase-2; Hexokinase PII; Hexokinase-B; EC 2.7.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P04807 hexokinase (EC 2.7.1.1) from Saccharomyces cerevisiae
PFams: Hexokinase_1, Hexokinase_2
486 amino acids: PaperBLAST, CDD, Compare to cluster

P35557 glucokinase (EC 2.7.1.1) from Homo sapiens
HXK4_HUMAN / P35557 Hexokinase-4; HK4; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-D; EC 2.7.1.1 from Homo sapiens (Human)
P35557 hexokinase (EC 2.7.1.1); glucokinase (EC 2.7.1.2) from Homo sapiens
Q53Y25 glucokinase (EC 2.7.1.2) from Homo sapiens
PFams: Hexokinase_1, Hexokinase_2
465 amino acids: PaperBLAST, CDD, Compare to cluster

HXK2_SCHPO / P50521 Hexokinase-2; EC 2.7.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
P50521 hexokinase (EC 2.7.1.1) from Schizosaccharomyces pombe
RF|NP_593865.1 hexokinase 2; EC 2.7.1.1; EC 2.7.1.2; EC 2.7.1.4; EC 2.7.1.7 from Schizosaccharomyces pombe
PFams: Hexokinase_1, Hexokinase_2
455 amino acids: PaperBLAST, CDD, Compare to cluster

Q02155 hexokinase (EC 2.7.1.1) from Plasmodium falciparum
PFams: Hexokinase_1, Hexokinase_2
493 amino acids: PaperBLAST, CDD, Compare to cluster

HXK1_SCHPO / Q09756 Hexokinase-1; EC 2.7.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Q09756 hexokinase (EC 2.7.1.1) from Schizosaccharomyces pombe
RF|NP_592948.1 hexokinase 1; EC 2.7.1.1; EC 2.7.1.2; EC 2.7.1.4; EC 2.7.1.7 from Schizosaccharomyces pombe
PFams: Hexokinase_1, Hexokinase_2
484 amino acids: PaperBLAST, CDD, Compare to cluster

HXK7_ORYSJ / Q1WM16 Hexokinase-7; Hexokinase-6; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q1WM16 hexokinase (EC 2.7.1.1) from Oryza sativa Japonica Group
PFams: Hexokinase_1, Hexokinase_2
463 amino acids: PaperBLAST, CDD, Compare to cluster

Q42525 fructokinase (EC 2.7.1.4; EC 2.7.1.1) from Arabidopsis thaliana
HXK1_ARATH / Q42525 Hexokinase-1; Protein GLUCOSE INSENSITIVE 2; EC 2.7.1.1 from Arabidopsis thaliana (Mouse-ear cress)
Q42525 hexokinase (EC 2.7.1.1) from Arabidopsis thaliana
PFams: Hexokinase_1, Hexokinase_2
496 amino acids: PaperBLAST, CDD, Compare to cluster

Q5CWT5 hexokinase (EC 2.7.1.1) from Cryptosporidium parvum
PFams: Hexokinase_1, Hexokinase_2
518 amino acids: PaperBLAST, CDD, Compare to cluster

HXK5_ORYSJ / Q5W676 Hexokinase-5; Hexokinase I; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q5W676 hexokinase (EC 2.7.1.1) from Oryza sativa
PFams: Hexokinase_1, Hexokinase_2
507 amino acids: PaperBLAST, CDD, Compare to cluster

Q6X271 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
513 amino acids: PaperBLAST, CDD, Compare to cluster

HXK1_ORYSJ / Q8LH82 Hexokinase-1; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q8LH82 hexokinase (EC 2.7.1.1) from Oryza sativa
PFams: Hexokinase_1, Hexokinase_2
498 amino acids: PaperBLAST, CDD, Compare to cluster

Q8ST54 hexokinase (EC 2.7.1.1) from Trypanosoma cruzi
PFams: Hexokinase_1, Hexokinase_2
471 amino acids: PaperBLAST, CDD, Compare to cluster

Q96VP5 hexokinase (EC 2.7.1.1) from Ogataea angusta
PFams: Hexokinase_1, Hexokinase_2
471 amino acids: PaperBLAST, CDD, Compare to cluster

V5KAK3 hexokinase (EC 2.7.1.1) from Branchiostoma japonicum
PFams: Hexokinase_1, Hexokinase_2
458 amino acids: PaperBLAST, CDD, Compare to cluster

CH_024045 hexokinase 1; EC 2.7.1.1 from Entamoeba histolytica
GI|1070151 hexokinase 1; EC 2.7.1.1 from Entamoeba histolytica
PFams: Hexokinase_1, Hexokinase_2
445 amino acids: PaperBLAST, CDD, Compare to cluster

CH_024046 hexokinase 2; EC 2.7.1.1 from Entamoeba histolytica
GI|1070153 hexokinase 2; EC 2.7.1.1 from Entamoeba histolytica
PFams: Hexokinase_1, Hexokinase_2
445 amino acids: PaperBLAST, CDD, Compare to cluster

GI|134057515 hexokinase; EC 2.7.1.1 from Aspergillus niger
PFams: Hexokinase_1, Hexokinase_2
490 amino acids: PaperBLAST, CDD, Compare to cluster

CH_122617 hexokinase; EC 2.7.1.1 from Emericella nidulans
PFams: Hexokinase_1, Hexokinase_2
490 amino acids: PaperBLAST, CDD, Compare to cluster

HXK_BRUMA / A0A0K0JFP3 Hexokinase; BmHK; EC 2.7.1.1 from Brugia malayi (Filarial nematode worm)
PFams: Hexokinase_1, Hexokinase_2
572 amino acids: PaperBLAST, CDD, Compare to cluster

HXK1_SOLTU / O64390 Hexokinase-1; StHK1; EC 2.7.1.1 from Solanum tuberosum (Potato)
O64390 hexokinase (EC 2.7.1.1) from Solanum tuberosum
PFams: Hexokinase_1, Hexokinase_2
498 amino acids: PaperBLAST, CDD, Compare to cluster

P17709 glucokinase (EC 2.7.1.1) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
HXKG_YEAST / P17709 Glucokinase-1; Glucose kinase 1; GLK-1; EC 2.7.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Hexokinase_1, Hexokinase_2
500 amino acids: PaperBLAST, CDD, Compare to cluster

HXK4_RAT / P17712 Hexokinase-4; HK4; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-D; EC 2.7.1.1 from Rattus norvegicus (Rat)
P17712 glucokinase (EC 2.7.1.2) from Rattus norvegicus
PFams: Hexokinase_1, Hexokinase_2
465 amino acids: PaperBLAST, CDD, Compare to cluster

HXK_KLULA / P33284 Hexokinase; EC 2.7.1.1 from Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
P33284 hexokinase (EC 2.7.1.1) from Kluyveromyces lactis
PFams: Hexokinase_1, Hexokinase_2
485 amino acids: PaperBLAST, CDD, Compare to cluster

HXK4_MOUSE / P52792 Hexokinase-4; HK4; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-D; EC 2.7.1.1 from Mus musculus (Mouse)
PFams: Hexokinase_1, Hexokinase_2
465 amino acids: PaperBLAST, CDD, Compare to cluster

HXKB_CANAL / P83776 Hexokinase-2; Cytoplasmic antigenic protein 3; Hexokinase PII; Hexokinase-B; EC 2.7.1.1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
PFams: Hexokinase_1, Hexokinase_2
484 amino acids: PaperBLAST, CDD, Compare to cluster

P93834 hexokinase (EC 2.7.1.1) from Arabidopsis thaliana
HXK2_ARATH / P93834 Hexokinase-2; EC 2.7.1.1 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Hexokinase_1, Hexokinase_2
502 amino acids: PaperBLAST, CDD, Compare to cluster

EMI2_YEAST / Q04409 Putative glucokinase-2; Early meiotic induction protein 2; Glucose kinase 2; GLK-2; EC 2.7.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Hexokinase_1, Hexokinase_2
500 amino acids: PaperBLAST, CDD, Compare to cluster

HXK8_ORYSJ / Q1WM15 Hexokinase-8; Hexokinase-4; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
PFams: Hexokinase_1, Hexokinase_2
458 amino acids: PaperBLAST, CDD, Compare to cluster

HXK_SCHMA / Q26609 Hexokinase; EC 2.7.1.1 from Schistosoma mansoni (Blood fluke)
PFams: Hexokinase_1, Hexokinase_2
451 amino acids: PaperBLAST, CDD, Compare to cluster

HXK3_ORYSJ / Q2KNB4 Hexokinase-3; Hexokinase-8; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
PFams: Hexokinase_1, Hexokinase_2
500 amino acids: PaperBLAST, CDD, Compare to cluster

HXK10_ORYSJ / Q2KNB5 Hexokinase-10; Hexokinase-7; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q2KNB5 hexokinase (EC 2.7.1.1) from Oryza sativa
PFams: Hexokinase_1, Hexokinase_2
504 amino acids: PaperBLAST, CDD, Compare to cluster

HXK9_ORYSJ / Q2KNB7 Hexokinase-9; Hexokinase-5; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
PFams: Hexokinase_1, Hexokinase_2
502 amino acids: PaperBLAST, CDD, Compare to cluster

HXK2_ORYSJ / Q2KNB9 Hexokinase-2; Hexokinase-3; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q2KNB9 hexokinase (EC 2.7.1.1) from Oryza sativa
PFams: Hexokinase_1, Hexokinase_2
494 amino acids: PaperBLAST, CDD, Compare to cluster

HXK4_ARATH / Q56XE8 Hexokinase-4; EC 2.7.1.1 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Hexokinase_1, Hexokinase_2
502 amino acids: PaperBLAST, CDD, Compare to cluster

HXKG_KLULA / Q6CUZ3 Glucokinase-1; Glucose kinase 1; GLK-1; Hexokinase GLK1; EC 2.7.1.2; EC 2.7.1.1 from Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
PFams: Hexokinase_1, Hexokinase_2
481 amino acids: PaperBLAST, CDD, Compare to cluster

Q6Q8A5 hexokinase (EC 2.7.1.1; EC 2.7.1.4; EC 2.7.1.7) from Nicotiana tabacum
HXK2_TOBAC / Q6Q8A5 Hexokinase-2, chloroplastic; NtHxK2; EC 2.7.1.1 from Nicotiana tabacum (Common tobacco)
Q6Q8A5 hexokinase (EC 2.7.1.1) from Nicotiana tabacum
PFams: Hexokinase_1, Hexokinase_2
499 amino acids: PaperBLAST, CDD, Compare to cluster

HXK4_ORYSJ / Q6Z398 Hexokinase-4, chloroplastic; Hexokinase II; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q6Z398 hexokinase (EC 2.7.1.1) from Oryza sativa
PFams: Hexokinase_1, Hexokinase_2
509 amino acids: PaperBLAST, CDD, Compare to cluster

HXK6_ORYSJ / Q8LQ68 Hexokinase-6; Hexokinase-2; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
PFams: Hexokinase_1, Hexokinase_2
506 amino acids: PaperBLAST, CDD, Compare to cluster

HXKG_ASPNG / Q92407 Glucokinase; Glucose kinase; GLK; Hexokinase glkA; EC 2.7.1.2; EC 2.7.1.1 from Aspergillus niger
PFams: Hexokinase_1, Hexokinase_2
495 amino acids: PaperBLAST, CDD, Compare to cluster

HXK3_ARATH / Q9LPS1 Hexokinase-3; EC 2.7.1.1 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Hexokinase_1, Hexokinase_2
498 amino acids: PaperBLAST, CDD, Compare to cluster

HXK1_SPIOL / Q9SEK3 Hexokinase-1; SoHxK1; EC 2.7.1.1 from Spinacia oleracea (Spinach)
Q9SEK3 hexokinase (EC 2.7.1.1) from Spinacia oleracea
PFams: Hexokinase_1, Hexokinase_2
498 amino acids: PaperBLAST, CDD, Compare to cluster

HXK2_SOLTU / Q9SQ76 Hexokinase-2; StHK2; EC 2.7.1.1 from Solanum tuberosum (Potato)
Q9SQ76 hexokinase (EC 2.7.1.1) from Solanum tuberosum
PFams: Hexokinase_1, Hexokinase_2
496 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 296-326 amino acids (not heteromeric)

Q5RLG0 hexokinase (EC 2.7.1.1) from Thermus caldophilus
PFams: ROK
302 amino acids: PaperBLAST, CDD, Compare to cluster

B1VZT1 glucokinase (EC 2.7.1.2) from Streptomyces griseus
PFams: ROK, Glucokinase
313 amino acids: PaperBLAST, CDD, Compare to cluster

P0A4E1 glucokinase (EC 2.7.1.2) from Streptomyces coelicolor
CH_017149 glucokinase; EC 2.7.1.2 from Streptomyces coelicolor
PFams: ROK, Glucokinase
317 amino acids: PaperBLAST, CDD, Compare to cluster

P54495 glucokinase (EC 2.7.1.1) from Bacillus subtilis (strain 168)
P54495 glucokinase (EC 2.7.1.2) from Bacillus subtilis
PFams: ROK
321 amino acids: PaperBLAST, CDD, Compare to cluster

Q5SLJ4 hexokinase (EC 2.7.1.1) from Thermus thermophilus
PFams: ROK
302 amino acids: PaperBLAST, CDD, Compare to cluster

Q7ZAH1 hexokinase (EC 2.7.1.1) from Thermoproteus tenax
PFams: ROK
301 amino acids: PaperBLAST, CDD, Compare to cluster

Q8RDE9 glucokinase (EC 2.7.1.2) from Caldanaerobacter subterraneus subsp. tengcongensis
PFams: ROK
315 amino acids: PaperBLAST, CDD, Compare to cluster

GI|1303865 glucokinase; EC 2.7.1.2 from Bacillus subtilis
PFams: ROK
321 amino acids: PaperBLAST, CDD, Compare to cluster

O31392 glucokinase (EC 2.7.1.2) from Bacillus megaterium
CH_014478 glucokinase; EC 2.7.1.2 from Bacillus megaterium
PFams: ROK
324 amino acids: PaperBLAST, CDD, Compare to cluster

GLK_PYRCJ / A3MUZ0 Glucokinase; ATP-dependent glucokinase; ATP-GLK; Glucose kinase; EC 2.7.1.2 from Pyrobaculum calidifontis (strain JCM 11548 / VA1)
PFams: ROK
296 amino acids: PaperBLAST, CDD, Compare to cluster

Q9X1I0 glucokinase subunit (EC 2.7.1.1) from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
GLK_THEMA / Q9X1I0 Glucokinase; ATP-dependent glucokinase; ATP-GLK; Glucose kinase; EC 2.7.1.2 from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
PFams: ROK
317 amino acids: PaperBLAST, CDD, Compare to cluster

GLK_AERPE / Q9YA47 Glucokinase; ATP-dependent glucokinase; ATP-GLK; Glucose kinase; EC 2.7.1.2 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
PFams: ROK
320 amino acids: PaperBLAST, CDD, Compare to cluster

Q5GBH5 N-acetylglucosamine kinase (EC 2.7.1.59) from Bacteroides fragilis
PFams: ROK
326 amino acids: PaperBLAST, CDD, Compare to cluster

Q8DVE8 glucokinase subunit (EC 2.7.1.1) from Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
PFams: ROK
323 amino acids: PaperBLAST, CDD, Compare to cluster

Sama_1405 glucokinase (EC 2.7.1.2) from Shewanella amazonensis SB2B
PFams: ROK, Glucokinase
310 amino acids: PaperBLAST, CDD, Compare to cluster

Sama_2231 glucokinase (EC 2.7.1.2) from Shewanella amazonensis SB2B
PFams: ROK, Glucokinase
299 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 915-974 amino acids (not heteromeric)

HXK1_RAT / P05708 Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I; Hexokinase-A; EC 2.7.1.1 from Rattus norvegicus (Rat)
P05708 hexokinase (EC 2.7.1.1) from Rattus norvegicus
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
918 amino acids: PaperBLAST, CDD, Compare to cluster

P19367 hexokinase-1 (EC 2.7.1.1) from Homo sapiens
HXK1_HUMAN / P19367 Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I; Hexokinase-A; EC 2.7.1.1 from Homo sapiens (Human)
P19367 hexokinase (EC 2.7.1.1) from Homo sapiens
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

HXK2_RAT / P27881 Hexokinase-2; Hexokinase type II; HK II; Hexokinase-B; EC 2.7.1.1 from Rattus norvegicus (Rat)
P27881 hexokinase (EC 2.7.1.1) from Rattus norvegicus
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

P52789 hexokinase-2 (EC 2.7.1.1) from Homo sapiens
HXK2_HUMAN / P52789 Hexokinase-2; Hexokinase type II; HK II; Hexokinase-B; Muscle form hexokinase; EC 2.7.1.1 from Homo sapiens (Human)
P52789 hexokinase (EC 2.7.1.1); glucokinase (EC 2.7.1.2) from Homo sapiens
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

Q5W5U3 hexokinase (EC 2.7.1.1) from Bos taurus
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

HXK2_MOUSE / O08528 Hexokinase-2; Hexokinase type II; HK II; EC 2.7.1.1 from Mus musculus (Mouse)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

HXK1_MOUSE / P17710 Hexokinase-1; Hexokinase type I; HK I; Hexokinase, tumor isozyme; EC 2.7.1.1 from Mus musculus (Mouse)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
974 amino acids: PaperBLAST, CDD, Compare to cluster

HXK3_RAT / P27926 Hexokinase-3; Hexokinase type III; HK III; Hexokinase-C; EC 2.7.1.1 from Rattus norvegicus (Rat)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
924 amino acids: PaperBLAST, CDD, Compare to cluster

P52790 hexokinase-3 (EC 2.7.1.1) from Homo sapiens
HXK3_HUMAN / P52790 Hexokinase-3; Hexokinase type III; HK III; Hexokinase-C; EC 2.7.1.1 from Homo sapiens (Human)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
923 amino acids: PaperBLAST, CDD, Compare to cluster

HKDC1_HUMAN / Q2TB90 Hexokinase HKDC1; Hexokinase domain-containing protein 1; EC 2.7.1.1 from Homo sapiens (Human)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

HKDC1_MOUSE / Q91W97 Hexokinase HKDC1; Hexokinase domain-containing protein 1; EC 2.7.1.1 from Mus musculus (Mouse)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
915 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 316-323 amino acids (not heteromeric)

A8LLL9 Glucokinase; EC=2.7.1.2
323 amino acids: PaperBLAST, CDD, Compare to cluster

I7DXX1 Glucokinase Glk; EC=2.7.1.2
316 amino acids: PaperBLAST, CDD, Compare to cluster

b2388 glucokinase (EC 2.7.1.1; EC 2.7.1.2; EC 2.7.1.8) from Escherichia coli K-12 substr. MG1655
P0A6V8 glucokinase (EC 2.7.1.1; EC 2.7.1.8) from Escherichia coli (strain K12)
PFams: Glucokinase
321 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_22685 Glucokinase (EC 2.7.1.2) from Pseudomonas simiae WCS417
PFams: Glucokinase
318 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/8 heteromeric)

A0SZU9 hexokinase (EC 2.7.1.1); glucokinase (EC 2.7.1.2) from Lysinibacillus sphaericus
PFams: ROK
291 amino acids: PaperBLAST, CDD

H6UH58 glucokinase (EC 2.7.1.2) from Staphylococcus aureus
PFams: Glucokinase, ROK
328 amino acids: PaperBLAST, CDD
(similar to BRENDA::B1VZT1 from Cluster 2, but similarity to seed sequence is below thresholds)

Q4E4E1 glucokinase (EC 2.7.1.2) from Trypanosoma cruzi
PFams: Glucokinase
376 amino acids: PaperBLAST, CDD

Q96Y14 hexokinase (EC 2.7.1.1) from Sulfurisphaera tokodaii
PFams: BcrAD_BadFG
299 amino acids: PaperBLAST, CDD

P9WIN1 polyphosphate-dependent glucokinase (EC 2.7.1.63) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PPGK_MYCTA / A5U654 Polyphosphate glucokinase; Poly(P) glucokinase; ATP-dependent glucokinase; Polyphosphate--glucose phosphotransferase; EC 2.7.1.63; EC 2.7.1.2 from Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
PPGK_MYCTU / P9WIN1 Polyphosphate glucokinase; Poly(P) glucokinase; ATP-dependent glucokinase; Polyphosphate--glucose phosphotransferase; EC 2.7.1.63; EC 2.7.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: ROK
265 amino acids: PaperBLAST, CDD

HXK1_CANAL / Q59RW5 N-acetylglucosamine kinase 1; GlcNAc kinase 1; Hexokinase 1; EC 2.7.1.59; EC 2.7.1.1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
PFams: Hexokinase_1, Hexokinase_2
493 amino acids: PaperBLAST, CDD

Q5GAN8 General specificity hexokinase
402 amino acids: PaperBLAST, CDD

E2RU42 glucokinase (EC 2.7.1.1) from Giardia intestinalis (strain ATCC 50803 / WB clone C6)
PFams: Glucokinase, ROK
343 amino acids: PaperBLAST, CDD