Clusters of Characterized Proteins

Clustering the characterized proteins for malK (trehalose ABC transporter, ATPase component MalK) in trehalose catabolism

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Definition of malK

• Curated sequence Q8DT25: MalK, component of Maltose/Maltotriose/maltodextrin (up to 7 glucose units) transporters MalXFGK (MsmK (3.A.1.1.28) can probably substitute for MalK; Webb et al., 2008)
• Curated sequence Q00752: MsmK aka SMU.882, component of The raffinose/stachyose transporter, MsmEFGK (MalK (3.A.1.1.27) can probably substitute for MsmK; Webb et al., 2008). This system may also transport melibiose, isomaltotriose and sucrose as well as isomaltosaccharides
• Comment: The related ATPase msmK can substitute for malK (PMC2223742)

Fetched 2 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 377-377 amino acids (heteromeric)

TC 3.A.1.1.28 / Q00752 MsmK aka SMU.882, component of The raffinose/stachyose transporter, MsmEFGK (MalK (3.A.1.1.27) can probably substitute for MsmK; Webb et al., 2008). This system may also transport melibiose, isomaltotriose and sucrose as well as isomaltosaccharides from Streptococcus mutans
PFams: ABC_tran, OB_MalK, TOBE_2, TOBE
Heteromeric, 377 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.1.27 / Q8DT25 MalK, component of Maltose/Maltotriose/maltodextrin (up to 7 glucose units) transporters MalXFGK (MsmK (3.A.1.1.28) can probably substitute for MalK; Webb et al., 2008) from Streptococcus mutans
PFams: ABC_tran, OB_MalK, CysA_C_terminal, TOBE_2, TOBE
Heteromeric, 377 amino acids: PaperBLAST, CDD, Compare to cluster