Clusters of Characterized Proteins
Clustering the characterized proteins for ptsG (glucose PTS, enzyme IICB) in trehalose catabolism
Or see other characterized proteins similar to ptsG
Or see all steps for trehalose catabolism
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Definition of ptsG
- Ignore hits to Q9AGA7 when looking for 'other' hits (PTS system alpha-glucoside-specific EIICB component; EC 2.7.1.-. The α-glucoside-specific IICB, AglB (transports glucose, methyl-α-glucoside, maltitol, isomaltose, trehalulose α(1→1), turanose α(1→3), maltulose α(1→4), leucrose α(1→5), and palatinose α(1→6), but not sucrose (most resembles 4.A.1.1.4 and 4.A.1.1.8))
- Curated sequence P69786: protein-Npi-phosphohistidine-D-glucose phosphotransferase (EC 2.7.1.199). PTS system glucose-specific EIICB component; EC 2.7.1.69. PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199. PTS system glucose-specific EIICB component PTGB aka PTSG aka GLCA aka UMG aka B1101, component of Glucose porter (PtsG; GlcA; Umg) (transports D-glucose and α-methyl-D-glucopyranoside). glucose-specific PTS enzyme IIBC component (EC 2.7.1.199). glucose-specific PTS enzyme IIBC component (EC 2.7.1.199)
- Curated sequence P37439: PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199
- Ignore hits to O51590 when looking for 'other' hits (Glucose-specific Enzyme IIBC of the PTS, PtsG)
- Ignore hits to P19642 when looking for 'other' hits (PTS system maltose- and glucose-specific EIICB component; EC 2.7.1.69. PTS system maltose-specific EIICB component; EC 2.7.1.208. Maltose porter (MalX). PTS enzyme IIBC component MalX. PTS enzyme IIBC component MalX)
- Comment: EII-CB proteins. Ignore O51590 (4.A.1.1.18) from Borrelia burgdorferi, which is not characterized and the EIIA component is uncertain. Ignore E. coli malX (P19642), which facilitates diffusion of glucose (no phosphorylation); its physiological function is unclear so it is not listed as a sole glucose transporter. Ignore PTUCB_KLEPN / Q9AGA7 from Klebsiella, as the EII-A component was not described
Fetched 2 sequences
Running BLASTp
Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences
Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism
Cluster 1 477-477 amino acids (1/2 heteromeric)
The first sequence in each cluster is the seed.b1101 glucose-specific PTS enzyme IIBC component (EC 2.7.1.199) from Escherichia coli K-12 substr. MG1655
P69786 glucose-specific PTS enzyme IIBC component (EC 2.7.1.199) from Escherichia coli (strain K12)
PTGCB_ECOLI / P69786 PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199 from Escherichia coli (strain K12)
P69786 protein-Npi-phosphohistidine-D-glucose phosphotransferase (EC 2.7.1.199) from Escherichia coli
TC 4.A.1.1.1 / P69786 PTS system glucose-specific EIICB component PTGB aka PTSG aka GLCA aka UMG aka B1101, component of Glucose porter (PtsG; GlcA; Umg) (transports D-glucose and α-methyl-D-glucopyranoside) from Escherichia coli
MB|P69786 PTS system glucose-specific EIICB component; EC 2.7.1.69 from Escherichia coli K12
PFams: PTS_EIIC, PTS_EIIB
Heteromeric, 477 amino acids: PaperBLAST, CDD, Compare to cluster
PTGCB_SALTY / P37439 PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: PTS_EIIC, PTS_EIIB
477 amino acids: PaperBLAST, CDD, Compare to cluster