Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for kyn (kynureninase) in L-tryptophan catabolism

Or see other characterized proteins similar to kyn

Or see all steps for L-tryptophan catabolism

Or cluster curated proteins matching a keyword

Definition of kyn

Curated proteins or TIGRFams with EC 3.7.1.3
Comment: 3-hydroxykynurenine hydrolase and kynurenine hydrolase are described by the same EC number.

Fetched 13 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 13 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 416-478 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

B7XB98 kynureninase (EC 3.7.1.3) from Bombyx mori
PFams: Aminotran_5
426 amino acids: PaperBLAST, CDD, Compare to cluster

Q16719 Kynureninase (EC 3.7.1.3) from Homo sapiens
KYNU_HUMAN / Q16719 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Homo sapiens (Human)
Q16719 kynureninase (EC 3.7.1.3) from Homo sapiens
PFams: Aminotran_5
465 amino acids: PaperBLAST, CDD, Compare to cluster

P70712 kynureninase subunit (EC 3.7.1.3) from Rattus norvegicus
KYNU_RAT / P70712 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Rattus norvegicus (Rat)
PFams: Aminotran_5
464 amino acids: PaperBLAST, CDD, Compare to cluster

P83788 kynureninase subunit (EC 3.7.1.3) from Pseudomonas fluorescens
KYNU_PSEFL / P83788 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Pseudomonas fluorescens
P83788 kynureninase (EC 3.7.1.3) from Pseudomonas fluorescens
PFams: Aminotran_5, DegT_DnrJ_EryC1
416 amino acids: PaperBLAST, CDD, Compare to cluster

KYNU_YEAST / Q05979 Kynureninase; Biosynthesis of nicotinic acid protein 5; L-kynurenine hydrolase; EC 3.7.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Aminotran_5
453 amino acids: PaperBLAST, CDD, Compare to cluster

KYNU_CAEEL / Q18026 Kynureninase; Abnormal fluorescence under UV illumination; L-kynurenine hydrolase; EC 3.7.1.3 from Caenorhabditis elegans
PFams: Aminotran_5
478 amino acids: PaperBLAST, CDD, Compare to cluster

KYNU_MOUSE / Q9CXF0 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Mus musculus (Mouse)
PFams: Aminotran_5
464 amino acids: PaperBLAST, CDD, Compare to cluster

D6R244 3-hydroxy-4-methyl-D-kynurenine hydrolase monomer (from HMM only) from Streptomyces anulatus
PFams: Aminotran_5
420 amino acids: PaperBLAST, CDD, Compare to cluster

BPHYT_RS16030 Kynureninase (EC 3.7.1.3) from Burkholderia phytofirmans PsJN
PFams: Aminotran_5
416 amino acids: PaperBLAST, CDD, Compare to cluster

RR42_RS15385 Kynureninase (EC 3.7.1.3) from Cupriavidus basilensis 4G11
PFams: Aminotran_5, DegT_DnrJ_EryC1
418 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_23650 Kynureninase (EC 3.7.1.3) from Pseudomonas simiae WCS417
PFams: Aminotran_5
416 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_4288 Kynureninase (EC 3.7.1.3) from Pseudomonas fluorescens GW456-L13
PFams: Aminotran_5
416 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_05935 Kynureninase (EC 3.7.1.3) from Pseudomonas fluorescens FW300-N2E3
PFams: Aminotran_5, DegT_DnrJ_EryC1
416 amino acids: PaperBLAST, CDD, Compare to cluster