GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for kynA (tryptophan 2,3-dioxygenase) in L-tryptophan catabolism

Or see other characterized proteins similar to kynA

Or see all steps for L-tryptophan catabolism

Or cluster curated proteins matching a keyword

Definition of kynA

Fetched 33 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 32 of these sequences

Found 3 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 378-454 amino acids (not heteromeric)

B3Y9H9 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Monodelphis domestica
PFams: IDO
404 amino acids: PaperBLAST, CDD, Compare to cluster

A2BD60 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Xenopus laevis
PFams: IDO
398 amino acids: PaperBLAST, CDD, Compare to cluster

A7SDW8 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Nematostella vectensis
PFams: IDO
395 amino acids: PaperBLAST, CDD, Compare to cluster

A9UVU0 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Monosiga brevicollis
PFams: IDO
378 amino acids: PaperBLAST, CDD, Compare to cluster

B3Y9H6 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Ornithorhynchus anatinus
PFams: IDO
410 amino acids: PaperBLAST, CDD, Compare to cluster

B3Y9H7 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Ornithorhynchus anatinus
PFams: IDO
413 amino acids: PaperBLAST, CDD, Compare to cluster

B3Y9H8 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Monodelphis domestica
PFams: IDO, DUF1864
399 amino acids: PaperBLAST, CDD, Compare to cluster

C3Y9Y8 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Branchiostoma floridae
PFams: IDO
396 amino acids: PaperBLAST, CDD, Compare to cluster

P14902 indoleamine 2,3-dioxygenase (EC 1.13.11.52; EC 1.13.11.11) from Homo sapiens
I23O1_HUMAN / P14902 Indoleamine 2,3-dioxygenase 1; IDO-1; Indoleamine-pyrrole 2,3-dioxygenase; EC 1.13.11.52 from Homo sapiens (Human)
P14902 tryptophan 2,3-dioxygenase (EC 1.13.11.11); indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Homo sapiens
PFams: IDO
403 amino acids: PaperBLAST, CDD, Compare to cluster

I23O1_MOUSE / P28776 Indoleamine 2,3-dioxygenase 1; IDO-1; Indoleamine-pyrrole 2,3-dioxygenase; EC 1.13.11.52 from Mus musculus (Mouse)
P28776 tryptophan 2,3-dioxygenase (EC 1.13.11.11); indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Mus musculus
PFams: IDO
407 amino acids: PaperBLAST, CDD, Compare to cluster

Q6F3I3 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Haliotis diversicolor
PFams: IDO
385 amino acids: PaperBLAST, CDD, Compare to cluster

I23O2_HUMAN / Q6ZQW0 Indoleamine 2,3-dioxygenase 2; IDO-2; Indoleamine 2,3-dioxygenase-like protein 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1; EC 1.13.11.- from Homo sapiens (Human)
Q6ZQW0 tryptophan 2,3-dioxygenase (EC 1.13.11.11); indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Homo sapiens
PFams: IDO
420 amino acids: PaperBLAST, CDD, Compare to cluster

Q9ERD9 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Rattus norvegicus
PFams: IDO
407 amino acids: PaperBLAST, CDD, Compare to cluster

W4ZK80 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Strongylocentrotus purpuratus
PFams: IDO
454 amino acids: PaperBLAST, CDD, Compare to cluster

I23O_YEAST / P47125 Indoleamine 2,3-dioxygenase; IDO; Biosynthesis of nicotinic acid protein 2; EC 1.13.11.52 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: IDO
453 amino acids: PaperBLAST, CDD, Compare to cluster

I23O2_MOUSE / Q8R0V5 Indoleamine 2,3-dioxygenase 2; IDO-2; Indoleamine 2,3-dioxygenase-like protein 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1; EC 1.13.11.- from Mus musculus (Mouse)
Q8R0V5 indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Mus musculus
PFams: IDO
405 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 298-455 amino acids (not heteromeric)

T23O_DROME / P20351 Tryptophan 2,3-dioxygenase; TDO; Protein vermilion; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase; EC 1.13.11.11 from Drosophila melanogaster (Fruit fly)
P20351 tryptophan 2,3-dioxygenase (EC 1.13.11.11); indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Drosophila melanogaster
PFams: Trp_dioxygenase
379 amino acids: PaperBLAST, CDD, Compare to cluster

T23O_RAT / P21643 Tryptophan 2,3-dioxygenase; TDO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase; EC 1.13.11.11 from Rattus norvegicus (Rat)
P21643 tryptophan 2,3-dioxygenase (EC 1.13.11.11); indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Rattus norvegicus
PFams: Trp_dioxygenase
406 amino acids: PaperBLAST, CDD, Compare to cluster

P48775 tryptophan 2,3-dioxygenase monomer (EC 1.13.11.11) from Homo sapiens
T23O_HUMAN / P48775 Tryptophan 2,3-dioxygenase; TDO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase; EC 1.13.11.11 from Homo sapiens (Human)
P48775 tryptophan 2,3-dioxygenase (EC 1.13.11.11); indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Homo sapiens
PFams: Trp_dioxygenase
406 amino acids: PaperBLAST, CDD, Compare to cluster

P48776 tryptophan 2,3-dioxygenase (EC 1.13.11.11); indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Mus musculus
PFams: Trp_dioxygenase
406 amino acids: PaperBLAST, CDD, Compare to cluster

T23O_CAEEL / Q09474 Tryptophan 2,3-dioxygenase; TDO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase; EC 1.13.11.11 from Caenorhabditis elegans
Q09474 tryptophan 2,3-dioxygenase (EC 1.13.11.11) from Caenorhabditis elegans
PFams: Trp_dioxygenase
403 amino acids: PaperBLAST, CDD, Compare to cluster

W4ZI02 tryptophan 2,3-dioxygenase (EC 1.13.11.11) from Strongylocentrotus purpuratus
PFams: Trp_dioxygenase
455 amino acids: PaperBLAST, CDD, Compare to cluster

T23O_AEDAE / Q17P71 Tryptophan 2,3-dioxygenase; TDO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase; EC 1.13.11.11 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
PFams: Trp_dioxygenase
393 amino acids: PaperBLAST, CDD, Compare to cluster

T23O_XANCP / Q8PDA8 Tryptophan 2,3-dioxygenase; TDO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase; EC 1.13.11.11 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Q8PDA8 tryptophan 2,3-dioxygenase (EC 1.13.11.11); indoleamine 2,3-dioxygenase (EC 1.13.11.52) from Xanthomonas campestris pv. campestris
CH_121344 tryptophan 2,3-dioxygenase; EC 1.13.11.11 from Xanthomonas campestris pv. campestris
PFams: Trp_dioxygenase, Trp_dioxygenase
298 amino acids: PaperBLAST, CDD, Compare to cluster

T23O_TRICA / Q95NN1 Tryptophan 2,3-dioxygenase; TDO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase; EC 1.13.11.11 from Tribolium castaneum (Red flour beetle)
PFams: Trp_dioxygenase
388 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 280-299 amino acids (not heteromeric)

AO353_05970 Tryptophan 2,3-dioxygenase (EC 1.13.11.11) from Pseudomonas fluorescens FW300-N2E3
PFams: Trp_dioxygenase, Trp_dioxygenase
288 amino acids: PaperBLAST, CDD, Compare to cluster

T23O_CUPMC / Q1LK00 Tryptophan 2,3-dioxygenase; TDO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase; EC 1.13.11.11 from Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) (Ralstonia metallidurans)
CH_121345 tryptophan 2,3-dioxygenase; EC 1.13.11.11 from Ralstonia metallidurans CH34
PFams: Trp_dioxygenase
299 amino acids: PaperBLAST, CDD, Compare to cluster

T23O_PSEFL / Q84HF6 Tryptophan 2,3-dioxygenase; TDO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase; EC 1.13.11.11 from Pseudomonas fluorescens
PFams: Trp_dioxygenase, Trp_dioxygenase
284 amino acids: PaperBLAST, CDD, Compare to cluster

D6R243 tryptophan 2,3-dioxygenase (EC 1.13.11.11) from Streptomyces anulatus
PFams: Trp_dioxygenase, Trp_dioxygenase
280 amino acids: PaperBLAST, CDD, Compare to cluster

RR42_RS15390 Tryptophan 2,3-dioxygenase (EC 1.13.11.11) from Cupriavidus basilensis 4G11
PFams: Trp_dioxygenase, Trp_dioxygenase
291 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_23705 Tryptophan 2,3-dioxygenase (EC 1.13.11.11) from Pseudomonas simiae WCS417
PFams: Trp_dioxygenase
285 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_4292 Tryptophan 2,3-dioxygenase (EC 1.13.11.11) from Pseudomonas fluorescens GW456-L13
PFams: Trp_dioxygenase, Trp_dioxygenase
284 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

A9V766 tryptophan 2,3-dioxygenase (EC 1.13.11.11) from Monosiga brevicollis
PFams: Trp_dioxygenase
546 amino acids: PaperBLAST, CDD