GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for kynB (kynurenine formamidase) in L-tryptophan catabolism

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Definition of kynB

Fetched 20 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 16 of these sequences

Found 2 clusters of similar sequences. Another 4 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 209-221 amino acids (not heteromeric)

KYNB_BURCJ / B4E9I9 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315))
B4E9I9 arylformamidase (EC 3.5.1.9) from Burkholderia cenocepacia
PFams: Cyclase
213 amino acids: PaperBLAST, CDD, Compare to cluster

KYNB_PSEAE / Q9I234 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9I234 arylformamidase (EC 3.5.1.9) from Pseudomonas aeruginosa
CH_121488 kynurenine formamidase; EC 3.5.1.9 from Pseudomonas aeruginosa
PFams: Cyclase
213 amino acids: PaperBLAST, CDD, Compare to cluster

KYNB_CUPMC / P0C8P4 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) (Ralstonia metallidurans)
CH_121487 kynurenine formamidase; EC 3.5.1.9 from Ralstonia metallidurans CH34
PFams: Cyclase
218 amino acids: PaperBLAST, CDD, Compare to cluster

KYNB_BACCR / Q81CK1 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
CH_121485 kynurenine formamidase; EC 3.5.1.9 from Bacillus cereus ATCC 14579
PFams: Cyclase
209 amino acids: PaperBLAST, CDD, Compare to cluster

KYNB_BACAN / Q81PP9 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Bacillus anthracis
Q81PP9 arylformamidase (EC 3.5.1.9) from Bacillus anthracis
PFams: Cyclase
209 amino acids: PaperBLAST, CDD, Compare to cluster

KYNB_PSEFL / Q84HF4 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Pseudomonas fluorescens
PFams: Cyclase
218 amino acids: PaperBLAST, CDD, Compare to cluster

BPHYT_RS16025 Kynurenine formamidase, bacterial (EC 3.5.1.9) from Burkholderia phytofirmans PsJN
PFams: Cyclase
212 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_23710 Kynurenine formamidase, bacterial (EC 3.5.1.9) from Pseudomonas simiae WCS417
PFams: Cyclase
216 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_4293 Kynurenine formamidase, bacterial (EC 3.5.1.9) from Pseudomonas fluorescens GW456-L13
PFams: Cyclase
221 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_05975 Kynurenine formamidase, bacterial (EC 3.5.1.9) from Pseudomonas fluorescens FW300-N2E3
PFams: Cyclase
221 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 293-319 amino acids (not heteromeric)

A0A287B5F1 arylformamidase (EC 3.5.1.9) from Sus scrofa
PFams: COesterase, Abhydrolase_3
319 amino acids: PaperBLAST, CDD, Compare to cluster

E1C2H6 arylformamidase (EC 3.5.1.9) from Gallus gallus
PFams: COesterase, Abhydrolase_3
293 amino acids: PaperBLAST, CDD, Compare to cluster

F6WFA7 arylformamidase (EC 3.5.1.9) from Equus caballus
PFams: COesterase, Abhydrolase_3, Peptidase_S9, FSH1
306 amino acids: PaperBLAST, CDD, Compare to cluster

M0RC77 arylformamidase (EC 3.5.1.9) from Rattus norvegicus
PFams: Abhydrolase_3
306 amino acids: PaperBLAST, CDD, Compare to cluster

Q8K4H1 arylformamidase (EC 3.5.1.9) from Mus musculus
KFA_MOUSE / Q8K4H1 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Mus musculus (Mouse)
Q8K4H1 arylformamidase (EC 3.5.1.9) from Mus musculus
PFams: COesterase, Abhydrolase_3, Peptidase_S9
305 amino acids: PaperBLAST, CDD, Compare to cluster

D6R242 arylformamidase (EC 3.5.1.9) from Streptomyces anulatus
PFams: Abhydrolase_3
304 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/4 heteromeric)

F5HBR2 arylformamidase (EC 3.5.1.9) from Neurospora crassa
403 amino acids: PaperBLAST, CDD

Q9X8R1 arylformamidase (EC 3.5.1.9) from Streptomyces coelicolor
PFams: Esterase, COesterase, Abhydrolase_3, Abhydrolase_6, Peptidase_S9
301 amino acids: PaperBLAST, CDD

KFA_YEAST / Q04066 Kynurenine formamidase; KFA; KFase; Arylformamidase; Biosynthesis of nicotinic acid protein 7; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Say1_Mug180, Abhydrolase_3
261 amino acids: PaperBLAST, CDD

KFA_DROME / Q9VMC9 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Drosophila melanogaster (Fruit fly)
Q9VMC9 arylformamidase (EC 3.5.1.9) from Drosophila melanogaster
PFams: Abhydrolase_3
300 amino acids: PaperBLAST, CDD