GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for aacS (acetoacetyl-CoA synthetase) in L-tyrosine catabolism

Or see other characterized proteins similar to aacS

Or see all steps for L-tyrosine catabolism

Or cluster curated proteins matching a keyword

Definition of aacS

Fetched 9 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 8 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 650-723 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

D6EQU8 acetoacetate-CoA ligase (EC 6.2.1.16) from Streptomyces lividans
PFams: ACAS_N, AMP-binding, AMP-binding_C
658 amino acids: PaperBLAST, CDD, Compare to cluster

AACS_HUMAN / Q86V21 Acetoacetyl-CoA synthetase; Acyl-CoA synthetase family member 1; Protein sur-5 homolog; EC 6.2.1.16 from Homo sapiens (Human)
Q86V21 acetoacetate-CoA ligase (EC 6.2.1.16) from Homo sapiens
PFams: ACAS_N, AMP-binding
672 amino acids: PaperBLAST, CDD, Compare to cluster

Q9D2R0 acetoacetate-CoA ligase (EC 6.2.1.16) from Mus musculus
PFams: ACAS_N, AMP-binding
672 amino acids: PaperBLAST, CDD, Compare to cluster

AACS_RAT / Q9JMI1 Acetoacetyl-CoA synthetase; EC 6.2.1.16 from Rattus norvegicus (Rat)
Q9JMI1 acetoacetyl-CoA synthase (EC 2.3.1.194) from Rattus norvegicus
PFams: ACAS_N, AMP-binding
672 amino acids: PaperBLAST, CDD, Compare to cluster

SMc00774 Acetoacetate--CoA ligase (EC 6.2.1.16) from Sinorhizobium meliloti 1021
AACS_RHIME / Q9Z3R3 Acetoacetyl-coenzyme A synthetase; Acetoacetyl-CoA synthetase; EC 6.2.1.16 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Q9Z3R3 acetoacetate-CoA ligase (EC 6.2.1.16) from Sinorhizobium meliloti
PFams: AMP-binding, AMP-binding_C
650 amino acids: PaperBLAST, CDD, Compare to cluster

VRTB_PENAE / D7PHZ3 Malonamoyl-CoA synthetase vrtB; Viridicatumtoxin synthesis protein B; EC 6.2.1.- (from HMM only) from Penicillium aethiopicum
PFams: ACAS_N, AMP-binding, AMP-binding_C
723 amino acids: PaperBLAST, CDD, Compare to cluster

SUR5_CAEEL / Q21166 Acetoacetyl-CoA synthetase; Suppressor of activated let-60 Ras protein 5; EC 6.2.1.16 from Caenorhabditis elegans
PFams: ACAS_N, AMP-binding, AMP-binding_C
700 amino acids: PaperBLAST, CDD, Compare to cluster

Q5P8R9 4-hydroxybenzoyl-acetyl-CoA synthetase (from HMM only) from Aromatoleum aromaticum (strain EbN1)
PFams: ACAS_N, AMP-binding
664 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

Ac3H11_3009 Acetoacetate--CoA ligase (EC 6.2.1.16) from Acidovorax sp. GW101-3H11
PFams: AMP-binding, AMP-binding_C
578 amino acids: PaperBLAST, CDD