Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for bch (3-hydroxyisobutyryl-CoA hydrolase) in L-valine catabolism

Or see other characterized proteins similar to bch

Or see all steps for L-valine catabolism

Or cluster curated proteins matching a keyword

Definition of bch

Curated proteins or TIGRFams with EC 3.1.2.4
Ignore hits to Q9SE41 when looking for 'other' hits (enoyl-CoA hydratase (EC 4.2.1.17))
Ignore hits to MONOMER-11695 when looking for 'other' hits (enoyl-CoA hydratase subunit (EC 4.2.1.17))

Fetched 13 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 13 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 348-502 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

Q5XIE6 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Rattus norvegicus
HIBCH_RAT / Q5XIE6 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Rattus norvegicus (Rat)
PFams: ECH_1, ECH_2
385 amino acids: PaperBLAST, CDD, Compare to cluster

Q81DR3 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Bacillus cereus
PFams: ECH_1, ECH_2
351 amino acids: PaperBLAST, CDD, Compare to cluster

HIBC1_ARATH / Q9LKJ1 3-hydroxyisobutyryl-CoA hydrolase 1; CoA-thioester hydrolase CHY1; EC 3.1.2.-; EC 3.1.2.4 from Arabidopsis thaliana (Mouse-ear cress)
Q9LKJ1 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Arabidopsis thaliana
PFams: ECH_1, ECH_2
378 amino acids: PaperBLAST, CDD, Compare to cluster

HIBCH_HUMAN / Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Homo sapiens (Human)
PFams: ECH_1, ECH_2
386 amino acids: PaperBLAST, CDD, Compare to cluster

Q5AI24 3-hydroxypropanonyl-CoA hydrolase (EC 3.1.2.4) from Candida albicans (strain SC5314 / ATCC MYA-2876)
PFams: ECH_2, ECH_1
502 amino acids: PaperBLAST, CDD, Compare to cluster

RR42_RS28545 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Cupriavidus basilensis 4G11
PFams: ECH_1, ECH_2
384 amino acids: PaperBLAST, CDD, Compare to cluster

PGA1_c17350 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Phaeobacter inhibens BS107
PFams: ECH_2, ECH_1
348 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_13835 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas simiae WCS417
PFams: ECH_1, ECH_2
367 amino acids: PaperBLAST, CDD, Compare to cluster

Psest_2439 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas stutzeri RCH2
PFams: ECH_1, ECH_2
364 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_2986 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens GW456-L13
PFams: ECH_1, ECH_2
356 amino acids: PaperBLAST, CDD, Compare to cluster

Pf1N1B4_4790 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens FW300-N1B4
PFams: ECH_1, ECH_2
356 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_25665 3-hydroxy-isobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens FW300-N2E3
PFams: ECH_1, ECH_2
368 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

HIBCH_YEAST / P28817 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; Mitochondrial small ribosomal subunit protein mS47; EC 3.1.2.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: ECH_1, ECH_2
500 amino acids: PaperBLAST, CDD
(similar to SwissProt::Q6NVY1 from Cluster 1, but similarity to seed sequence is below thresholds)