Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for mmsB (3-hydroxyisobutyrate dehydrogenase) in L-valine catabolism

Or see other characterized proteins similar to mmsB

Or see all steps for L-valine catabolism

Or cluster curated proteins matching a keyword

Definition of mmsB

Curated proteins or TIGRFams with EC 1.1.1.31
Ignore hits to D5MU22 when looking for 'other' hits (aldehyde oxidase (EC 1.2.3.1))
Comment: D5MU22 is probably mmsB but is misannotated in BRENDA

Fetched 7 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 7 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 294-336 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

SERDH_PSEAE / Q9I5I6 NAD-dependent L-serine dehydrogenase; L-serine 3-dehydrogenase (NAD(+)); EC 1.1.1.387 (from HMM only) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9I5I6 L-serine 3-dehydrogenase (NAD+) (EC 1.1.1.387) from Pseudomonas aeruginosa
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
298 amino acids: PaperBLAST, CDD, Compare to cluster

MMSB_PSEAE / P28811 3-hydroxyisobutyrate dehydrogenase; HIBADH; EC 1.1.1.31 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: NAD_binding_2, F420_oxidored, NAD_binding_11
298 amino acids: PaperBLAST, CDD, Compare to cluster

3HIDH_HUMAN / P31937 3-hydroxyisobutyrate dehydrogenase, mitochondrial; HIBADH; EC 1.1.1.31 from Homo sapiens (Human)
PFams: 2-Hacid_dh_C, F420_oxidored, NAD_binding_2, NAD_binding_11
336 amino acids: PaperBLAST, CDD, Compare to cluster

Q76KL5 3-hydroxyisobutyrate dehydrogenase subunit (EC 1.1.1.31) from Pseudomonas putida
Q76KL5 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) from Pseudomonas putida
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
295 amino acids: PaperBLAST, CDD, Compare to cluster

Psest_2438 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) from Pseudomonas stutzeri RCH2
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
296 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_5145 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) from Pseudomonas fluorescens GW456-L13
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
295 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_05985 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) from Pseudomonas fluorescens FW300-N2E3
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
294 amino acids: PaperBLAST, CDD, Compare to cluster