Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for gyaR (glyoxylate reductase) in D-xylose catabolism

Or see other characterized proteins similar to gyaR

Or see all steps for D-xylose catabolism

Or cluster curated proteins matching a keyword

Definition of gyaR

Curated proteins or TIGRFams with EC 1.1.1.26
Ignore hits to items matching 1.1.1.79 when looking for 'other' hits
Comment: The NADP based glyoxylate reductase (EC 1.1.1.79) is probably biased in the wrong direction for glycolate oxidation, so do not include, but ignore homology to it.

Fetched 6 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 4 of these sequences

Found 1 clusters of similar sequences. Another 2 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 328-386 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

GYAR_THELN / Q9C4M5 Glyoxylate reductase; EC 1.1.1.26 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C)
Q9C4M5 glyoxylate reductase (EC 1.1.1.26) from Thermococcus litoralis
PFams: 2-Hacid_dh, 2-Hacid_dh_C, IlvN, NAD_binding_2
331 amino acids: PaperBLAST, CDD, Compare to cluster

Q9C9W5 hydroxypyruvate reductase (EC 1.1.1.29) from Arabidopsis thaliana
HPR1_ARATH / Q9C9W5 Glycerate dehydrogenase HPR, peroxisomal; GDH; NADH-dependent hydroxypyruvate reductase 1; AtHPR1; HPR 1; EC 1.1.1.29 from Arabidopsis thaliana (Mouse-ear cress)
Q9C9W5 glyoxylate reductase (EC 1.1.1.26); glycerate dehydrogenase (EC 1.1.1.29); hydroxypyruvate reductase (EC 1.1.1.81) from Arabidopsis thaliana
PFams: 2-Hacid_dh, 2-Hacid_dh_C
386 amino acids: PaperBLAST, CDD, Compare to cluster

P53839 glyoxylate reductase 1 (EC 1.1.1.26) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
GOR1_YEAST / P53839 Glyoxylate reductase 1; EC 1.1.1.26 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: 2-Hacid_dh, 2-Hacid_dh_C
350 amino acids: PaperBLAST, CDD, Compare to cluster

Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.81; EC 1.1.1.79) from Homo sapiens
GRHPR_HUMAN / Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human)
Q9UBQ7 glyoxylate reductase (EC 1.1.1.26); glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Homo sapiens
PFams: 2-Hacid_dh, 2-Hacid_dh_C, F420_oxidored, NAD_binding_2
328 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/2 heteromeric)

Q97U35 glycolate dehydrogenase (EC 1.1.1.26) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Q97U35 glyoxylate reductase (EC 1.1.1.26) from Saccharolobus solfataricus
PFams: 2-Hacid_dh, 2-Hacid_dh_C
300 amino acids: PaperBLAST, CDD

Q9LSV0 succinate semialdehyde reductase (NADPH) from Arabidopsis thaliana
GLYR1_ARATH / Q9LSV0 Glyoxylate/succinic semialdehyde reductase 1; AtGLYR1; AtGR1; SSA reductase 1; Gamma-hydroxybutyrate dehydrogenase; AtGHBDH; EC 1.1.1.79; EC 1.1.1.n11 from Arabidopsis thaliana (Mouse-ear cress)
Q9LSV0 glyoxylate reductase (EC 1.1.1.26); 4-hydroxybutyrate dehydrogenase (EC 1.1.1.61); glyoxylate reductase (NADP+) (EC 1.1.1.79) from Arabidopsis thaliana
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
289 amino acids: PaperBLAST, CDD