Clusters of Characterized Proteins

Clustering the characterized proteins for xad (D-xylonate dehydratase) in D-xylose catabolism

Or see other characterized proteins similar to xad

Or see all steps for D-xylose catabolism

Or cluster curated proteins matching a keyword

Definition of xad

• Curated proteins or TIGRFams with EC 4.2.1.82
• UniProt sequence D8IWS7_HERSS: SubName: Full=Dihydroxyacid dehydratase/phosphogluconate dehydratase protein {ECO:0000313|EMBL:ADJ65964.1}; EC=4.2.1.9 {ECO:0000313|EMBL:ADJ65964.1};
• Comment: Watanabe et al (PMC6336799) show that C785_RS00855 = WP_039783171.1 = UPI0004007277 is D-xylonate dehydratase (xad); this is 98% identical to D8IWS7_HERSS, so use that identifier.

Fetched 9 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 9 of these sequences

Found 3 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 591-595 amino acids (not heteromeric)

XYLD_CAUVC / Q9A9Z2 D-xylonate dehydratase; XyDHT; Gluconate dehydratase; EC 4.2.1.82; EC 4.2.1.39 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus)
Q9A9Z2 xylonate dehydratase (EC 4.2.1.82) from Caulobacter vibrioides
PFams: ILVD_EDD
595 amino acids: PaperBLAST, CDD, Compare to cluster

D8IWS7_HERSS Dihydroxyacid dehydratase/phosphogluconate dehydratase protein; EC=4.2.1.9
594 amino acids: PaperBLAST, CDD, Compare to cluster

CCNA_00862 Xylonate dehydratase (EC 4.2.1.82) from Caulobacter crescentus NA1000
A0A0H3C6H6 xylonate dehydratase monomer (EC 4.2.1.82) from Caulobacter vibrioides (strain NA1000 / CB15N)
PFams: ILVD_EDD
591 amino acids: PaperBLAST, CDD, Compare to cluster

AO356_28760 Xylonate dehydratase (EC 4.2.1.82) from Pseudomonas fluorescens FW300-N2C3
PFams: ILVD_EDD
594 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_1668 Xylonate dehydratase (EC 4.2.1.82) from Pseudomonas fluorescens FW300-N2E2
PFams: ILVD_EDD
594 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 393-412 amino acids (not heteromeric)

D4GP40 D-xylonate dehydratase subunit (EC 4.2.1.82) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)
XAD_HALVD / D4GP40 D-xylonate dehydratase; XAD; EC 4.2.1.82 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
D4GP40 xylonate dehydratase (EC 4.2.1.82) from Haloferax volcanii
PFams: MR_MLE_N, MR_MLE_C
412 amino acids: PaperBLAST, CDD, Compare to cluster

Q97VG1 D-xylonate dehydratase subunit (EC 4.2.1.25; EC 4.2.1.82) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
PFams: MR_MLE_N, MR_MLE_C
393 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 655-655 amino acids (not heteromeric)

b4297 KpLE2 phage-like element; D-xylonate dehydratase (EC 4.2.1.82) from Escherichia coli K-12 substr. MG1655
P39358 KpLE2 phage-like element; D-xylonate dehydratase (EC 4.2.1.82) from Escherichia coli (strain K12)
YJHG_ECOLI / P39358 D-xylonate dehydratase YjhG; EC 4.2.1.82 from Escherichia coli (strain K12)
P39358 xylonate dehydratase (EC 4.2.1.82) from Escherichia coli
PFams: ILVD_EDD
655 amino acids: PaperBLAST, CDD, Compare to cluster

b0269 CP4-6 prophage; D-xylonate dehydratase (EC 4.2.1.82) from Escherichia coli K-12 substr. MG1655
P77596 CP4-6 prophage; D-xylonate dehydratase (EC 4.2.1.82) from Escherichia coli (strain K12)
YAGF_ECOLI / P77596 D-xylonate dehydratase YagF; EC 4.2.1.82 from Escherichia coli (strain K12)
PFams: ILVD_EDD
655 amino acids: PaperBLAST, CDD, Compare to cluster