Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for xdhA (xylitol dehydrogenase) in D-xylose catabolism

Or see other characterized proteins similar to xdhA

Or see all steps for D-xylose catabolism

Or cluster curated proteins matching a keyword

Definition of xdhA

Curated proteins or TIGRFams with EC 1.1.1.9
Ignore hits to items matching 1.1.1.14 when looking for 'other' hits
Ignore hits to items matching xylulose reductase when looking for 'other' hits
Comment: L-iditol 2-dehydrogenases (EC 1.1.1.14) often act on xylitol as well, so are ignored. There's also some xylulose reductases annotated but without an EC number.

Fetched 24 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 22 of these sequences

Found 1 clusters of similar sequences. Another 2 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 338-368 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

Q06004 glucitol dehydrogenase monomer (EC 1.1.1.9; EC 1.1.1.14) from Bacillus subtilis (strain 168)
DHSO_BACSU / Q06004 Sorbitol dehydrogenase; SDH; Glucitol dehydrogenase; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Bacillus subtilis (strain 168)
GI|304153 L-iditol 2-dehydrogenase; EC 1.1.1.14 from Bacillus subtilis subsp. subtilis str. 168
PFams: ADH_N, ADH_zinc_N
353 amino acids: PaperBLAST, CDD, Compare to cluster

A0A1B4XTS0 L-arabinitol 4-dehydrogenase (EC 1.1.1.12); D-xylulose reductase (EC 1.1.1.9) from Meyerozyma caribbica
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
362 amino acids: PaperBLAST, CDD, Compare to cluster

P22144 D-xylulose reductase (EC 1.1.1.9) from Scheffersomyces stipitis
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
363 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO1_YEAST / P35497 Sorbitol dehydrogenase 1; SDH 1; Polyol dehydrogenase; Xylitol dehydrogenase; EC 1.1.1.-; EC 1.1.1.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P35497 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Saccharomyces cerevisiae
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
357 amino acids: PaperBLAST, CDD, Compare to cluster

Q2K0Q7 D-xylulose reductase (EC 1.1.1.9) from Rhizobium etli
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
347 amino acids: PaperBLAST, CDD, Compare to cluster

Q6KAV2 D-xylulose reductase (EC 1.1.1.9) from Blastobotrys adeninivorans
PFams: ADH_N, ADH_zinc_N
368 amino acids: PaperBLAST, CDD, Compare to cluster

Q86ZV0 NAD⁺-dependent xylitol dehydrogenase (EC 1.1.1.9) from Aspergillus oryzae (strain ATCC 42149 / RIB 40)
XYL2_ASPOR / Q86ZV0 D-xylulose reductase A; Xylitol dehydrogenase A; EC 1.1.1.9 from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Q86ZV0 D-xylulose reductase (EC 1.1.1.9) from Aspergillus oryzae
GI|83774265 xylitol dehydrogenase; EC 1.1.1.9 from Aspergillus oryzae
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
358 amino acids: PaperBLAST, CDD, Compare to cluster

S6BFC0 D-xylulose reductase (EC 1.1.1.9) from Rhizomucor pusillus
PFams: ADH_N, ADH_zinc_N
363 amino acids: PaperBLAST, CDD, Compare to cluster

A0QXD8 erythritol/L-threitol dehydrogenase (EC 1.1.1.56; EC 1.1.1.12; EC 1.1.1.9) from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
ELTD_MYCS2 / A0QXD8 Erythritol/L-threitol dehydrogenase; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
PFams: ADH_N, ADH_zinc_N
362 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_SHEEP / P07846 Sorbitol dehydrogenase; SDH; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Ovis aries (Sheep)
PFams: ADH_N, Glu_dehyd_C, AlaDh_PNT_C, ADH_zinc_N
354 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_RAT / P27867 Sorbitol dehydrogenase; SDH; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Rattus norvegicus (Rat)
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
357 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_HUMAN / Q00796 Sorbitol dehydrogenase; SDH; (R,R)-butanediol dehydrogenase; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Ribitol dehydrogenase; RDH; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.4; EC 1.1.1.14; EC 1.1.1.56; EC 1.1.1.9 from Homo sapiens (Human)
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
357 amino acids: PaperBLAST, CDD, Compare to cluster

XYL2_YEAST / Q07993 D-xylulose reductase; Xylitol dehydrogenase; XDH; EC 1.1.1.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
356 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_BOVIN / Q58D31 Sorbitol dehydrogenase; SDH; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Bos taurus (Bovine)
PFams: ADH_N, Glu_dehyd_C, AlaDh_PNT_C, ADH_zinc_N
356 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_MOUSE / Q64442 Sorbitol dehydrogenase; SDH; SORD; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Mus musculus (Mouse)
PFams: ADH_N, Glu_dehyd_C, AlaDh_PNT_C, ADH_zinc_N
357 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_ARATH / Q9FJ95 Sorbitol dehydrogenase; SDH; Polyol dehydrogenase; Ribitol dehydrogenase; RDH; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.56; EC 1.1.1.9 from Arabidopsis thaliana (Mouse-ear cress)
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N, ADH_zinc_N_2
364 amino acids: PaperBLAST, CDD, Compare to cluster

Q59545 xylitol dehydrogenase (EC 1.1.1.9) from Morganella morganii
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
338 amino acids: PaperBLAST, CDD, Compare to cluster

Q876R2 D-sorbitol dehydrogenase (EC 1.1.1.14; EC 1.1.1.9) from Hypocrea jecorina
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
363 amino acids: PaperBLAST, CDD, Compare to cluster

BPHYT_RS16050 xylitol 2-dehydrogenase (EC 1.1.1.9) from Burkholderia phytofirmans PsJN
PFams: ADH_N, ADH_zinc_N
365 amino acids: PaperBLAST, CDD, Compare to cluster

Dshi_0551 D-xylulose reductase (EC 1.1.1.9) from Dinoroseobacter shibae DFL-12
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N, ADH_zinc_N_2
347 amino acids: PaperBLAST, CDD, Compare to cluster

HSERO_RS17015 L-iditol 2-dehydrogenase (EC 1.1.1.14); D-xylulose reductase (EC 1.1.1.9) from Herbaspirillum seropedicae SmR1
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
345 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_17720 xylitol 2-dehydrogenase (EC 1.1.1.9) from Pseudomonas simiae WCS417
PFams: ADH_N, ADH_zinc_N
359 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/2 heteromeric)

Q8GR61 D-xylulose reductase (EC 1.1.1.9) from Gluconobacter oxydans
PFams: adh_short, KR, Epimerase, adh_short_C2
262 amino acids: PaperBLAST, CDD

XYL2_PIG / P83049 D-xylulose reductase; Xylitol dehydrogenase; XDH; EC 1.1.1.9 from Sus scrofa (Pig)
134 amino acids: PaperBLAST, CDD