Clusters of Characterized Proteins

Clustering the characterized proteins for xylF (ABC transporter for xylose, substrate binding component xylF) in D-xylose catabolism

Or see other characterized proteins similar to xylF

Or see all steps for D-xylose catabolism

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Definition of xylF

• Curated sequence CH_003787: D-xylose ABC transporter, periplasmic D-xylose-binding protein. XylF aka XYLT aka B3566, component of Xylose porter. xylose ABC transporter periplasmic binding protein (EC 7.5.2.13; EC 7.5.2.10). xylose ABC transporter periplasmic binding protein (EC 7.5.2.13)
• Curated sequence A6LW10: D-xylose ABC transporter, periplasmic substrate-binding protein, component of Xylose transporter, XylFGH (XylF (R), 359 aas; XylG (C), 525 aas; XylH (M), 389 aas
• Curated sequence P25548: CVE1 aka ChvE aka ATU2348 aka AGR_C_4267, component of Multiple sugar (arabinose, xylose, galactose, glucose, fucose) putative porter
• Curated sequence G4FGN5: LacI family transcriptional regulator, component of Glucose porter. Also bind xylose (Boucher and Noll 2011). Induced by glucose (Frock et al. 2012). Directly regulated by glucose-responsive regulator GluR
• Ignore hits to P54083 when looking for 'other' hits (Multiple sugar-binding periplasmic protein SbpA; Sugar-binding protein A)
• Comment: T. maritima has a diverged SBP, Tmari_1858 (G4FGN5). Tmari_1858 is sometimes annotated as gluE, and is glucose induced. But the Km for xylose is quite low, so, considered it a xylose transporter as well. Ignore P54083 (sbpA from A. brasilensis), not known if it transports xylose or not; close homolog HSERO_RS05190 is mildly important for fitness during growth on xylose, so, it may transport xylose.

Fetched 4 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 3 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 330-359 amino acids (heteromeric)

b3566 xylose ABC transporter periplasmic binding protein (EC 7.5.2.13; EC 7.5.2.10) from Escherichia coli K-12 substr. MG1655
P37387 xylose ABC transporter periplasmic binding protein (EC 7.5.2.13) from Escherichia coli (strain K12)
TC 3.A.1.2.4 / P37387 XylF aka XYLT aka B3566, component of Xylose porter from Escherichia coli
GB|AAC76590.1 D-xylose ABC transporter, periplasmic D-xylose-binding protein from Escherichia coli K12
PFams: Peripla_BP_4, Peripla_BP_1
Heteromeric, 330 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.2.26 / A6LW10 D-xylose ABC transporter, periplasmic substrate-binding protein, component of Xylose transporter, XylFGH (XylF (R), 359 aas; XylG (C), 525 aas; XylH (M), 389 aas from Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)
PFams: Peripla_BP_4, Peripla_BP_1
Heteromeric, 359 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.2.5 / P25548 CVE1 aka ChvE aka ATU2348 aka AGR_C_4267, component of Multiple sugar (arabinose, xylose, galactose, glucose, fucose) putative porter from Agrobacterium tumefaciens
PFams: Peripla_BP_1, Peripla_BP_4
Heteromeric, 354 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (1/1 heteromeric)

TC 3.A.1.2.20 / G4FGN5 LacI family transcriptional regulator, component of Glucose porter. Also bind xylose (Boucher and Noll 2011). Induced by glucose (Frock et al. 2012). Directly regulated by glucose-responsive regulator GluR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
PFams: Peripla_BP_1, Peripla_BP_4, ABC_sub_bind
Heteromeric, 343 amino acids: PaperBLAST, CDD