Clusters of Characterized Proteins

PaperBLAST – Find papers about a protein or its homologs

Clusters of Characterized Proteins

Searching for 1.1.1.18

Found 58 characterized proteins with matching descriptions. 0 of these are heteromeric.

Fetched 58 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 54 of these sequences

Found 8 clusters of similar sequences. Another 5 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 274-331 amino acids (not heteromeric)

E3W861 carbonyl reductase (NADPH) (EC 1.1.1.184) from Bacillus sp. (in: Bacteria)
PFams: Aldo_ket_red
280 amino acids: PaperBLAST, CDD, Compare to cluster

P15121 aldose reductase from Homo sapiens
ALDR_HUMAN / P15121 Aldo-keto reductase family 1 member B1; Aldehyde reductase; Aldose reductase; AR; EC 1.1.1.300; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.21 from Homo sapiens (Human)
P15121 prostaglandin-F synthase (EC 1.1.1.188); aldehyde reductase (EC 1.1.1.21) from Homo sapiens
PFams: Aldo_ket_red
316 amino acids: PaperBLAST, CDD, Compare to cluster

P16116 prostaglandin-F synthase (EC 1.1.1.188); aldehyde reductase (EC 1.1.1.21) from Bos taurus
PFams: Aldo_ket_red
315 amino acids: PaperBLAST, CDD, Compare to cluster

PGFS_LEIMA / P22045 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Leishmania major
P22045 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania major
PFams: Aldo_ket_red
284 amino acids: PaperBLAST, CDD, Compare to cluster

P42330 Aldo-keto reductase family 1 member C3 (EC 1.1.1.213; EC 1.1.1.239; EC 1.1.1.64; EC 1.1.1.112; EC 1.1.1.50; EC 1.3.1.20; EC 1.1.1.188) from Homo sapiens
AK1C3_HUMAN / P42330 Aldo-keto reductase family 1 member C3; 17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2; 3-alpha-HSD type 2; Chlordecone reductase homolog HAKRb; Dihydrodiol dehydrogenase 3; DD-3; DD3; Dihydrodiol dehydrogenase type I; HA1753; Indanol dehydrogenase; Prostaglandin F synthase; PGFS; Testosterone 17-beta-dehydrogenase 5; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; EC 1.-.-.-; EC 1.1.1.357; EC 1.1.1.112; EC 1.1.1.188; EC 1.1.1.239; EC 1.1.1.64; EC 1.3.1.20 from Homo sapiens (Human)
P42330 prostaglandin-F synthase (EC 1.1.1.188); aldehyde reductase (EC 1.1.1.21); 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) (EC 1.1.1.239); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3(or 17)beta-hydroxysteroid dehydrogenase (EC 1.1.1.51); testosterone 17beta-dehydrogenase (NADP+) (EC 1.1.1.64) from Homo sapiens
PFams: Aldo_ket_red
323 amino acids: PaperBLAST, CDD, Compare to cluster

Q2TJA5 prostaglandin-F synthase (EC 1.1.1.188) from Sus scrofa
PFams: Aldo_ket_red
322 amino acids: PaperBLAST, CDD, Compare to cluster

Q4DJ07 prostaglandin-F synthase (EC 1.1.1.188) from Trypanosoma cruzi
PFams: Aldo_ket_red
283 amino acids: PaperBLAST, CDD, Compare to cluster

Q5FT75 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans
PFams: Aldo_ket_red
279 amino acids: PaperBLAST, CDD, Compare to cluster

Q5FYA7 prostaglandin-F synthase (EC 1.1.1.188) from Canis lupus familiaris
PFams: Aldo_ket_red
324 amino acids: PaperBLAST, CDD, Compare to cluster

Q7S3U4 carbonyl reductase (NADPH) (EC 1.1.1.184) from Neurospora crassa
PFams: Aldo_ket_red
331 amino acids: PaperBLAST, CDD, Compare to cluster

Q9X265 carbonyl reductase (NADPH) (EC 1.1.1.184) from Thermotoga maritima
PFams: Aldo_ket_red
274 amino acids: PaperBLAST, CDD, Compare to cluster

AKR_SYNY3 / P74308 Aldo/keto reductase slr0942; AKR; AKR3G1; EC 1.1.1.184 from Synechocystis sp. (strain PCC 6803 / Kazusa)
PFams: Aldo_ket_red
327 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 259-289 amino acids (not heteromeric)

Q9JJN7 carbonyl reductase (NADPH) (EC 1.1.1.184) from Cricetulus griseus
PFams: adh_short, KR, adh_short_C2, adh_short_C2, adh_short
277 amino acids: PaperBLAST, CDD, Compare to cluster

B2GV72 carbonyl reductase (NADPH) (EC 1.1.1.184) from Rattus norvegicus
PFams: adh_short, KR, adh_short_C2, adh_short_C2, adh_short
277 amino acids: PaperBLAST, CDD, Compare to cluster

F1N8Y3 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gallus gallus
PFams: adh_short, KR, adh_short_C2
276 amino acids: PaperBLAST, CDD, Compare to cluster

F1N9C1 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gallus gallus
PFams: adh_short, KR, adh_short_C2
259 amino acids: PaperBLAST, CDD, Compare to cluster

J9P7P2 carbonyl reductase (NADPH) (EC 1.1.1.184) from Canis lupus familiaris
PFams: adh_short, KR, adh_short_C2
277 amino acids: PaperBLAST, CDD, Compare to cluster

CBR3_HUMAN / O75828 Carbonyl reductase [NADPH] 3; NADPH-dependent carbonyl reductase 3; Short chain dehydrogenase/reductase family 21C member 2; EC 1.1.1.184 from Homo sapiens (Human)
O75828 carbonyl reductase (NADPH) (EC 1.1.1.184) from Homo sapiens
PFams: adh_short, KR, adh_short_C2, adh_short
277 amino acids: PaperBLAST, CDD, Compare to cluster

CBR1_HUMAN / P16152 Carbonyl reductase [NADPH] 1; 15-hydroxyprostaglandin dehydrogenase [NADP(+)]; NADPH-dependent carbonyl reductase 1; Prostaglandin 9-ketoreductase; Prostaglandin-E(2) 9-reductase; Short chain dehydrogenase/reductase family 21C member 1; EC 1.1.1.184; EC 1.1.1.197; EC 1.1.1.189 from Homo sapiens (Human)
P16152 carbonyl reductase (NADPH) (EC 1.1.1.184) from Homo sapiens
PFams: adh_short, KR, adh_short_C2
277 amino acids: PaperBLAST, CDD, Compare to cluster

P48758 carbonyl reductase (NADPH) (EC 1.1.1.184) from Mus musculus
PFams: adh_short, KR, adh_short_C2
277 amino acids: PaperBLAST, CDD, Compare to cluster

CBR1_PIG / Q28960 Carbonyl reductase [NADPH] 1; 15-hydroxyprostaglandin dehydrogenase [NADP(+)]; 20-beta-hydroxysteroid dehydrogenase; NADPH-dependent carbonyl reductase 1; Prostaglandin 9-ketoreductase; Prostaglandin-E(2) 9-reductase; EC 1.1.1.184; EC 1.1.1.197; EC 1.1.1.189 from Sus scrofa (Pig)
Q28960 carbonyl reductase (NADPH) (EC 1.1.1.184); prostaglandin-E2 9-reductase (EC 1.1.1.189) from Sus scrofa
PFams: adh_short, Epimerase, KR, adh_short_C2
289 amino acids: PaperBLAST, CDD, Compare to cluster

Q924V2 carbonyl reductase (NADPH) (EC 1.1.1.184) from Cricetulus griseus
PFams: adh_short, KR, adh_short_C2
277 amino acids: PaperBLAST, CDD, Compare to cluster

Q924V3 carbonyl reductase (NADPH) (EC 1.1.1.184) from Cricetulus griseus
PFams: adh_short, Epimerase, KR, adh_short_C2
277 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 336-346 amino acids (not heteromeric)

E1U887 inositol 2-dehydrogenase (EC 1.1.1.18) from Lactobacillus casei
PFams: GFO_IDH_MocA
346 amino acids: PaperBLAST, CDD, Compare to cluster

P26935 inositol 2-dehydrogenase monomer (EC 1.1.1.18; EC 1.1.1.369) from Bacillus subtilis (strain 168)
IOLG_BACSU / P26935 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; Myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; MI 2-dehydrogenase/DCI 3-dehydrogenase; EC 1.1.1.18; EC 1.1.1.369 from Bacillus subtilis (strain 168)
P26935 inositol 2-dehydrogenase (EC 1.1.1.18); D-chiro-inositol 1-dehydrogenase (EC 1.1.1.369) from Bacillus subtilis
PFams: GFO_IDH_MocA, F420_oxidored, GFO_IDH_MocA_C
344 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0H3FQ94 myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Klebsiella aerogenes (strain ATCC 13048 / DSM 30053 / JCM 1235 / KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006)
PFams: GFO_IDH_MocA, GFO_IDH_MocA_C
337 amino acids: PaperBLAST, CDD, Compare to cluster

BWI76_RS03095 Inositol 2-dehydrogenase (EC 1.1.1.18) from Klebsiella michiganensis M5al
PFams: GFO_IDH_MocA, GFO_IDH_MocA_C
337 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_11875 Inositol 2-dehydrogenase (EC 1.1.1.18) from Pseudomonas simiae WCS417
PFams: GFO_IDH_MocA, GFO_IDH_MocA_C
336 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_21365 Inositol 2-dehydrogenase (EC 1.1.1.18) from Pseudomonas fluorescens FW300-N2E3
PFams: GFO_IDH_MocA, GFO_IDH_MocA_C
336 amino acids: PaperBLAST, CDD, Compare to cluster

AO356_23190 Inositol 2-dehydrogenase (EC 1.1.1.18) from Pseudomonas fluorescens FW300-N2C3
PFams: GFO_IDH_MocA, GFO_IDH_MocA_C
336 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 244-282 amino acids (not heteromeric)

DHRS4_HUMAN / Q9BTZ2 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; SCAD-SRL; Short chain dehydrogenase/reductase family 25C member 2; Short-chain dehydrogenase/reductase family member 4; EC 1.1.1.184 from Homo sapiens (Human)
Q9BTZ2 NADP-retinol dehydrogenase (EC 1.1.1.300) from Homo sapiens
PFams: adh_short, KR, adh_short_C2
278 amino acids: PaperBLAST, CDD, Compare to cluster

A3GF07 carbonyl reductase (NADPH) (EC 1.1.1.184) from Scheffersomyces stipitis
PFams: adh_short, KR, adh_short_C2
282 amino acids: PaperBLAST, CDD, Compare to cluster

Q9Y8Y1 carbonyl reductase (NADPH) (EC 1.1.1.184) from Aeropyrum pernix
PFams: adh_short, KR, adh_short_C2
250 amino acids: PaperBLAST, CDD, Compare to cluster

DHRS4_CAEEL / G5EGA6 Dehydrogenase/reductase SDR family member 4; EC 1.1.1.184 from Caenorhabditis elegans
PFams: adh_short, KR, adh_short_C2
260 amino acids: PaperBLAST, CDD, Compare to cluster

CBR2_MOUSE / P08074 Carbonyl reductase [NADPH] 2; Adipocyte protein P27; AP27; Lung carbonyl reductase; LCR; NADPH-dependent carbonyl reductase 2; EC 1.1.1.184 from Mus musculus (Mouse)
PFams: adh_short, KR, adh_short_C2
244 amino acids: PaperBLAST, CDD, Compare to cluster

DHRS4_PIG / Q8WNV7 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NDRD; Peroxisomal short-chain alcohol dehydrogenase; PSCD; EC 1.1.1.184 from Sus scrofa (Pig)
PFams: adh_short, KR, adh_short_C2
279 amino acids: PaperBLAST, CDD, Compare to cluster

DHRS4_RABIT / Q9GKX2 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NDRD; Peroxisomal short-chain alcohol dehydrogenase; PSCD; rabNRDR; EC 1.1.1.184 from Oryctolagus cuniculus (Rabbit)
PFams: adh_short, KR, adh_short_C2
260 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 339-360 amino acids (not heteromeric)

K9RZL7 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla citriodora
PFams: ADH_N, ADH_zinc_N
360 amino acids: PaperBLAST, CDD, Compare to cluster

K9S0X0 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla setoyensis
PFams: ADH_N, ADH_zinc_N
360 amino acids: PaperBLAST, CDD, Compare to cluster

K9S1J6 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla frutescens
PFams: ADH_N, ADH_zinc_N
360 amino acids: PaperBLAST, CDD, Compare to cluster

b4269 aldehyde reductase, NADPH-dependent (EC 1.1.1.2) from Escherichia coli K-12 substr. MG1655
P27250 aldehyde reductase, NADPH-dependent (EC 1.1.1.2) from Escherichia coli (strain K12)
AHR_ECOLI / P27250 Aldehyde reductase Ahr; Zinc-dependent alcohol dehydrogenase Ahr; EC 1.1.1.2 from Escherichia coli (strain K12)
P27250 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Escherichia coli
PFams: ADH_N, AlaDh_PNT_C, ADH_zinc_N, ADH_zinc_N_2
339 amino acids: PaperBLAST, CDD, Compare to cluster

Q2KNL5 geraniol dehydrogenase (EC 1.1.1.183) from Ocimum basilicum
CADH1_OCIBA / Q2KNL5 Cinnamyl alcohol dehydrogenase 1; CAD 1; ObaCAD1; EC 1.1.1.195 from Ocimum basilicum (Sweet basil)
PFams: ADH_N, ADH_zinc_N
357 amino acids: PaperBLAST, CDD, Compare to cluster

Q2KNL6 geraniol dehydrogenase (EC 1.1.1.183) from Ocimum basilicum
GEDH1_OCIBA / Q2KNL6 Geraniol dehydrogenase 1; ObaGEDH1; EC 1.1.1.183 from Ocimum basilicum (Sweet basil)
Q2KNL6 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Ocimum basilicum
PFams: ADH_N, ADH_zinc_N
360 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 6 329-350 amino acids (not heteromeric)

SM_b20899 Inositol 2-dehydrogenase (EC 1.1.1.18) from Sinorhizobium meliloti 1021
MI2D_RHIME / O68965 Inositol 2-dehydrogenase; Myo-inositol 2-dehydrogenase; MI-dehydrogenase; EC 1.1.1.18 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
O68965 inositol 2-dehydrogenase (EC 1.1.1.18) from Sinorhizobium meliloti
PFams: GFO_IDH_MocA, F420_oxidored, GFO_IDH_MocA_C
330 amino acids: PaperBLAST, CDD, Compare to cluster

E1U888 inositol 2-dehydrogenase (EC 1.1.1.18) from Lactobacillus casei
PFams: GFO_IDH_MocA, GFO_IDH_MocA_C
350 amino acids: PaperBLAST, CDD, Compare to cluster

Q9EZV8 inositol 2-dehydrogenase (EC 1.1.1.18) from Sinorhizobium fredii
PFams: GFO_IDH_MocA, F420_oxidored, GFO_IDH_MocA_C
329 amino acids: PaperBLAST, CDD, Compare to cluster

Q9WYP5 myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
IOLG_THEMA / Q9WYP5 Myo-inositol 2-dehydrogenase; EC 1.1.1.18 from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Q9WYP5 D-chiro-inositol 1-dehydrogenase (EC 1.1.1.369) from Thermotoga maritima
PFams: GFO_IDH_MocA, GFO_IDH_MocA_C
334 amino acids: PaperBLAST, CDD, Compare to cluster

HSERO_RS12095 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Herbaspirillum seropedicae SmR1
PFams: GFO_IDH_MocA
330 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 7 338-369 amino acids (not heteromeric)

3BHS7_RAT / O35048 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; C(27) 3-beta-HSD; Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase; Confluent 3Y1 cell-associated 2; EC 1.1.1.-; EC 1.1.1.181 from Rattus norvegicus (Rat)
PFams: KR, 3Beta_HSD, Epimerase, GDP_Man_Dehyd, NmrA, Polysacc_synt_2, RmlD_sub_bind, NAD_binding_4, NAD_binding_10, 3Beta_HSD
338 amino acids: PaperBLAST, CDD, Compare to cluster

3BHS7_MOUSE / Q9EQC1 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; C(27) 3-beta-HSD; Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase; EC 1.1.1.-; EC 1.1.1.181 from Mus musculus (Mouse)
PFams: KR, 3Beta_HSD, Epimerase, GDP_Man_Dehyd, NmrA, Polysacc_synt_2, RmlD_sub_bind, NAD_binding_4, NAD_binding_10
369 amino acids: PaperBLAST, CDD, Compare to cluster

3BHS7_HUMAN / Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; C(27) 3-beta-HSD; Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase; EC 1.1.1.-; EC 1.1.1.181 from Homo sapiens (Human)
PFams: KR, 3Beta_HSD, Epimerase, GDP_Man_Dehyd, NmrA, Polysacc_synt_2, RmlD_sub_bind, NAD_binding_4, NAD_binding_10
369 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 8 344-344 amino acids (not heteromeric)

A0A0E4AX59 carbonyl reductase (NADPH) (EC 1.1.1.184); methylglyoxal reductase (NADPH) (EC 1.1.1.283) from Kluyveromyces marxianus
PFams: 3Beta_HSD, Epimerase, GDP_Man_Dehyd, NAD_binding_4
344 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0E4AY21 carbonyl reductase (NADPH) (EC 1.1.1.184); methylglyoxal reductase (NADPH) (EC 1.1.1.283) from Kluyveromyces marxianus
PFams: 3Beta_HSD, Epimerase, GDP_Man_Dehyd
344 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/5 heteromeric)

A1X808 carbonyl reductase (NADPH) (EC 1.1.1.184) from Candida parapsilosis CCTCC M203011
PFams: ADH_N, AlaDh_PNT_C, ADH_zinc_N, ADH_zinc_N_2
336 amino acids: PaperBLAST, CDD

Q5FQJ0 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans
PFams: Aldo_ket_red
332 amino acids: PaperBLAST, CDD

Q9C4B3 carbonyl reductase (NADPH) (EC 1.1.1.184) from Starmerella magnoliae
PFams: adh_short, KR, adh_short_C2
283 amino acids: PaperBLAST, CDD
(similar to BRENDA::A3GF07 from Cluster 4, but similarity to seed sequence is below thresholds)

PXL2B_PIG / A9CQL8 Prostamide/prostaglandin F synthase; Prostamide/PG F synthase; Prostamide/PGF synthase; Peroxiredoxin-like 2B; EC 1.11.1.20 from Sus scrofa (Pig)
A9CQL8 prostaglandin-F synthase (EC 1.1.1.188); prostamide/prostaglandin F2alpha synthase (EC 1.11.1.20) from Sus scrofa
PFams: AhpC-TSA_2
202 amino acids: PaperBLAST, CDD

Q9JRN7 GDP-4-keto-6-deoxy-D-mannose reductase (EC 1.1.1.187) from Aggregatibacter actinomycetemcomitans
TLD_AGGAC / Q9JRN7 GDP-6-deoxy-D-talose 4-dehydrogenase; GDP-4-keto-6-deoxy-D-mannose reductase; EC 1.1.1.135 from Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans)
PFams: RmlD_sub_bind, Epimerase, 3Beta_HSD, Polysacc_synt_2, GDP_Man_Dehyd, NAD_binding_4
294 amino acids: PaperBLAST, CDD