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Clusters of Characterized Proteins

Searching for 1.1.1.35

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Found 56 characterized proteins with matching descriptions. 3 of these are heteromeric.

Fetched 56 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 46 of these sequences

Found 8 clusters of similar sequences. Another 11 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 706-729 amino acids (3/14 heteromeric)

ECHP_RAT / P07896 Peroxisomal bifunctional enzyme; PBE; PBFE; EC 4.2.1.17; EC 5.3.3.8; EC 1.1.1.35 from Rattus norvegicus (Rat)
P07896 enoyl-CoA hydratase (EC 4.2.1.17) from Rattus norvegicus
RF|NP_598290.1 noyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase/3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35; EC 4.2.1.17; EC 5.3.3.8 from Rattus norvegicus
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH, 3HCDH
722 amino acids: PaperBLAST, CDD, Compare to cluster

MFP2_ARATH / Q9ZPI5 Peroxisomal fatty acid beta-oxidation multifunctional protein MFP2; AtMPF2; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Arabidopsis thaliana (Mouse-ear cress)
Q9ZPI5 enoyl-CoA hydratase (EC 4.2.1.17) from Arabidopsis thaliana
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
725 amino acids: PaperBLAST, CDD, Compare to cluster

b2341 3-hydroxyacyl-CoA dehydrogenase FadJ (EC 1.1.1.35; EC 1.1.1.211; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8) from Escherichia coli K-12 substr. MG1655
FADJ_ECOLI / P77399 Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 1.1.1.35 from Escherichia coli (strain K12)
P77399 3-hydroxyacyl-CoA dehydrogenase FadJ (EC 1.1.1.35; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8) from Escherichia coli (strain K12)
RF|NP_416843 fatty acid oxidation complex subunit alpha; EC 1.1.1.35; EC 4.2.1.17; EC 5.1.2.3 from Escherichia coli K12
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH, 3HCDH
Heteromeric, 714 amino acids: PaperBLAST, CDD, Compare to cluster

b3846 dodecenoyl-CoA δ-isomerase, enoyl-CoA hydratase, 3-hydroxybutyryl-CoA epimerase, 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35; EC 1.1.1.211; EC 4.2.1.17; EC 5.3.3.8; EC 5.1.2.3) from Escherichia coli K-12 substr. MG1655
FADB_ECOLI / P21177 Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Escherichia coli (strain K12)
P21177 dodecenoyl-CoA δ-isomerase, enoyl-CoA hydratase, 3-hydroxybutyryl-CoA epimerase, 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35; EC 4.2.1.17; EC 5.3.3.8; EC 5.1.2.3) from Escherichia coli (strain K12)
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH, 3HCDH
Heteromeric, 729 amino acids: PaperBLAST, CDD, Compare to cluster

FADB_PSEFR / P28793 Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Pseudomonas fragi
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
Heteromeric, 715 amino acids: PaperBLAST, CDD, Compare to cluster

ECHP_HUMAN / Q08426 Peroxisomal bifunctional enzyme; PBE; PBFE; EC 4.2.1.17; EC 5.3.3.8; EC 1.1.1.35 from Homo sapiens (Human)
Q08426 peroxisomal bifunctional enzyme (EC 4.2.1.17; EC 1.1.1.35) from Homo sapiens
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH, 3HCDH
723 amino acids: PaperBLAST, CDD, Compare to cluster

MFPA_CUCSA / Q39659 Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Cucumis sativus (Cucumber)
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
725 amino acids: PaperBLAST, CDD, Compare to cluster

MFP_ORYSJ / Q8W1L6 Peroxisomal fatty acid beta-oxidation multifunctional protein; MFP; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Oryza sativa subsp. japonica (Rice)
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
726 amino acids: PaperBLAST, CDD, Compare to cluster

AIM1_ARATH / Q9ZPI6 Peroxisomal fatty acid beta-oxidation multifunctional protein AIM1; Protein ABNORMAL INFLORESCENCE MERISTEM 1; AtAIM1; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Arabidopsis thaliana (Mouse-ear cress)
Q9ZPI6 peroxisomal fatty acid β-oxidation multifunctional protein AIM1 (EC 4.2.1.17) from Arabidopsis thaliana
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
721 amino acids: PaperBLAST, CDD, Compare to cluster

Q88L02 FadB (EC 5.3.3.8; EC 1.1.1.35; EC 5.1.2.3; EC 4.2.1.17; EC 1.1.1.36) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
715 amino acids: PaperBLAST, CDD, Compare to cluster

Q9HZJ2 fatty acid oxidation complex α subunit (EC 1.1.1.35; EC 4.2.1.17) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
715 amino acids: PaperBLAST, CDD, Compare to cluster

Shewana3_0024 Enoyl-CoA hydratase (EC 4.2.1.17); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Shewanella sp. ANA-3
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
716 amino acids: PaperBLAST, CDD, Compare to cluster

BPHYT_RS13545 3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.35) from Burkholderia phytofirmans PsJN
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
706 amino acids: PaperBLAST, CDD, Compare to cluster

Sama_0032 Enoyl-CoA hydratase (EC 4.2.1.17); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Shewanella amazonensis SB2B
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
716 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 279-314 amino acids (not heteromeric)

C4IEM5 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Clostridium butyricum
PFams: 3HCDH_N, 3HCDH
282 amino acids: PaperBLAST, CDD, Compare to cluster

P34439 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Caenorhabditis elegans
PFams: 3HCDH_N, NAD_binding_2, 3HCDH
298 amino acids: PaperBLAST, CDD, Compare to cluster

FADB2_MYCTU / P9WNP7 3-hydroxybutyryl-CoA dehydrogenase; Beta-hydroxybutyryl-CoA dehydrogenase; BHBD; EC 1.1.1.157 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WNP7 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Mycobacterium tuberculosis
PFams: 3HCDH_N, 3HCDH
286 amino acids: PaperBLAST, CDD, Compare to cluster

Q0KEY8 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Cupriavidus necator
PFams: 3HCDH_N, 3HCDH
284 amino acids: PaperBLAST, CDD, Compare to cluster

HCDH_HUMAN / Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; HCDH; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35 from Homo sapiens (Human)
Q16836 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Homo sapiens
Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (EC 1.1.1.35) from Homo sapiens
PFams: 3HCDH_N, UDPG_MGDP_dh_N, 3HCDH
314 amino acids: PaperBLAST, CDD, Compare to cluster

HBD_CLOAB / P52041 3-hydroxybutyryl-CoA dehydrogenase; Beta-hydroxybutyryl-CoA dehydrogenase; BHBD; EC 1.1.1.157 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
P52041 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.35) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
CH_091789 3-hydroxybutyryl-CoA dehydrogenase; EC 1.1.1.157 from Clostridium acetobutylicum
PFams: 3HCDH_N, UDPG_MGDP_dh_N, 3HCDH
282 amino acids: PaperBLAST, CDD, Compare to cluster

HCDH_PIG / P00348 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; HCDH; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35 from Sus scrofa (Pig)
PFams: Pyr_redox_2, 3HCDH_N, Pyr_redox, 3HCDH
314 amino acids: PaperBLAST, CDD, Compare to cluster

HBD_SYNWW / Q0AVM2 3-hydroxybutyryl-CoA dehydrogenase; EC 1.1.1.35 from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
PFams: 3HCDH_N, 3HCDH
279 amino acids: PaperBLAST, CDD, Compare to cluster

Q8RMI3 3-hydroxybutyryl-CoA dehydrogenase subunit (EC 1.1.1.35) from Clostridium beijerinckii
PFams: 3HCDH_N, 3HCDH
282 amino acids: PaperBLAST, CDD, Compare to cluster

A2SP28 (S)-3-hydroxybutanoyl-CoA dehydrogeanse (EC 1.1.1.35) from Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1)
PFams: 3HCDH_N, 3HCDH
285 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 304-323 amino acids (not heteromeric)

AK1C4_HUMAN / P17516 Aldo-keto reductase family 1 member C4; 3-alpha-HSD1; 3-alpha-hydroxysteroid dehydrogenase type I; Chlordecone reductase; CDR; Dihydrodiol dehydrogenase 4; DD-4; DD4; HAKRA; EC 1.1.1.-; EC 1.1.1.357; EC 1.1.1.225 from Homo sapiens (Human)
P17516 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) from Homo sapiens
P17516 Aldo-keto reductase family 1 member C4 (EC 1.1.1.213; EC 1.3.1.20; EC 1.1.1.225; EC 1.1.1.50) from Homo sapiens
PFams: Aldo_ket_red
323 amino acids: PaperBLAST, CDD, Compare to cluster

AK1C3_HUMAN / P42330 Aldo-keto reductase family 1 member C3; 17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2; 3-alpha-HSD type 2; Chlordecone reductase homolog HAKRb; Dihydrodiol dehydrogenase 3; DD-3; DD3; Dihydrodiol dehydrogenase type I; HA1753; Indanol dehydrogenase; Prostaglandin F synthase; PGFS; Testosterone 17-beta-dehydrogenase 5; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; EC 1.-.-.-; EC 1.1.1.357; EC 1.1.1.112; EC 1.1.1.188; EC 1.1.1.239; EC 1.1.1.64; EC 1.3.1.20 from Homo sapiens (Human)
P42330 prostaglandin-F synthase (EC 1.1.1.188); aldehyde reductase (EC 1.1.1.21); 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) (EC 1.1.1.239); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3(or 17)beta-hydroxysteroid dehydrogenase (EC 1.1.1.51); testosterone 17beta-dehydrogenase (NADP+) (EC 1.1.1.64) from Homo sapiens
P42330 Aldo-keto reductase family 1 member C3 (EC 1.1.1.213; EC 1.1.1.239; EC 1.1.1.64; EC 1.1.1.112; EC 1.1.1.50; EC 1.3.1.20; EC 1.1.1.188) from Homo sapiens
PFams: Aldo_ket_red
323 amino acids: PaperBLAST, CDD, Compare to cluster

AK1C2_HUMAN / P52895 Aldo-keto reductase family 1 member C2; 3-alpha-HSD3; Chlordecone reductase homolog HAKRD; Dihydrodiol dehydrogenase 2; DD-2; DD2; Dihydrodiol dehydrogenase/bile acid-binding protein; DD/BABP; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Type III 3-alpha-hydroxysteroid dehydrogenase; EC 1.-.-.-; EC 1.3.1.20; EC 1.1.1.357 from Homo sapiens (Human)
P52895 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens
P52895 3α hydroxysteroid dehydrogenase III (EC 1.1.1.52; EC 1.1.1.395; EC 1.1.1.213; EC 1.3.1.20; EC 1.1.1.50) from Homo sapiens
PFams: Aldo_ket_red
323 amino acids: PaperBLAST, CDD, Compare to cluster

AK1C1_HUMAN / Q04828 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Chlordecone reductase homolog HAKRC; Dihydrodiol dehydrogenase 1/2; DD1/DD2; High-affinity hepatic bile acid-binding protein; HBAB; Indanol dehydrogenase; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; EC 1.1.1.-; EC 1.1.1.149; EC 1.1.1.112; EC 1.3.1.20 from Homo sapiens (Human)
Q04828 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens
Q04828 Aldo-keto reductase family 1 member C1 (EC 1.1.1.213; EC 1.1.1.112; EC 1.1.1.149; EC 1.3.1.20) from Homo sapiens
PFams: Aldo_ket_red
323 amino acids: PaperBLAST, CDD, Compare to cluster

T2HVB4 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) from Oryctolagus cuniculus
PFams: Aldo_ket_red
322 amino acids: PaperBLAST, CDD, Compare to cluster

CPRC2_CANPA / Q76L36 NADPH-dependent conjugated polyketone reductase C2; CPR; 2-dehydropantolactone reductase; 2-dehydropantolactone reductase (A-specific); Ketopantoyl-lactone reductase; EC 1.1.1.358; EC 1.1.1.168 from Candida parapsilosis (Yeast)
Q76L36 2-dehydropantolactone reductase (Si-specific) (EC 1.1.1.214); 2-dehydropantolactone reductase (EC 1.1.1.358) from Candida parapsilosis
PFams: Aldo_ket_red
307 amino acids: PaperBLAST, CDD, Compare to cluster

CPRC1_CANPA / Q76L37 NADPH-dependent conjugated polyketone reductase C1; CPR; 2-dehydropantolactone reductase (A-specific); Ketopantoyl-lactone reductase; EC 1.1.1.168 from Candida parapsilosis (Yeast)
Q76L37 2-dehydropantolactone reductase (Si-specific) (EC 1.1.1.214); 2-dehydropantolactone reductase (EC 1.1.1.358) from Candida parapsilosis
PFams: Aldo_ket_red
304 amino acids: PaperBLAST, CDD, Compare to cluster

AK1C4_MACFU / Q95JH4 Aldo-keto reductase family 1 member C4; 3-alpha-HSD1; 3-alpha-hydroxysteroid dehydrogenase type I; Chlordecone reductase; CDR; Dihydrodiol dehydrogenase 4; DD-4; DD4; EC 1.1.1.-; EC 1.1.1.357; EC 1.1.1.225 from Macaca fuscata fuscata (Japanese macaque)
PFams: Aldo_ket_red
323 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 255-286 amino acids (not heteromeric)

HCD2_DROME / O18404 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Scully protein; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.178 from Drosophila melanogaster (Fruit fly)
PFams: KR, adh_short, Epimerase, adh_short_C2
255 amino acids: PaperBLAST, CDD, Compare to cluster

HCD2_HUMAN / Q99714 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.178 from Homo sapiens (Human)
Q99714 GDP-6-deoxy-D-talose 4-dehydrogenase (EC 1.1.1.135); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (EC 1.1.1.178) from Bos taurus
Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.35) from Homo sapiens
PFams: adh_short, KR, adh_short_C2
261 amino acids: PaperBLAST, CDD, Compare to cluster

Q9I1X3 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) from Pseudomonas aeruginosa
PFams: adh_short, KR, adh_short_C2
286 amino acids: PaperBLAST, CDD, Compare to cluster

HCD2_MOUSE / O08756 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.178 from Mus musculus (Mouse)
PFams: adh_short, KR, adh_short_C2
261 amino acids: PaperBLAST, CDD, Compare to cluster

AFLH_ASPPU / P87017 5'-hydroxyaverantin dehydrogenase; HAVN dehydrogenase; Aflatoxin biosynthesis protein H; EC 1.1.1.352 from Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1)
P87017 5'-hydroxyaverantin dehydrogenase (EC 1.1.1.352) from Aspergillus parasiticus
P87017 hydroxyaverantin dehydrogenase subunit (EC 1.1.1.352) from Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1)
PFams: adh_short, adh_short_C2
278 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 319-319 amino acids (not heteromeric)

Q84X95 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Brassica napus
PFams: adh_short, KR, adh_short_C2
319 amino acids: PaperBLAST, CDD, Compare to cluster

Q84X96 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Brassica napus
PFams: adh_short, KR, adh_short_C2
319 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 6 361-366 amino acids (not heteromeric)

GLCDH_SACSO / O93715 Glucose 1-dehydrogenase; GDH; GlcDH; Aldose 1-dehydrogenase [NAD(P)(+)]; Galactose 1-dehydrogenase; EC 1.1.1.47; EC 1.1.1.359; EC 1.1.1.120; EC 1.1.1.48 from Saccharolobus solfataricus (Sulfolobus solfataricus)
O93715 aldose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.359) from Saccharolobus solfataricus
Q7LYI9 aldose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.359) from Saccharolobus solfataricus
O93715 aldose 1-dehydrogenase subunit (EC 1.1.1.376; EC 1.1.1.359; EC 1.1.1.119) from Saccharolobus solfataricus
PFams: ADH_N, Glu_dehyd_C
366 amino acids: PaperBLAST, CDD, Compare to cluster

GLCDH_THEAC / P13203 Glucose 1-dehydrogenase; GDH; GlcDH; Galactose 1-dehydrogenase; EC 1.1.1.47; EC 1.1.1.120; EC 1.1.1.48 from Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
P13203 aldose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.359) from Thermoplasma acidophilum
P13203 glucose dehydrogenase subunit (EC 1.1.1.119) from Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
PFams: ADH_N, Glu_dehyd_C
361 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 7 789-807 amino acids (not heteromeric)

Q0KEG0 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); enoyl-CoA hydratase (EC 4.2.1.17) from Cupriavidus necator
PFams: 3HCDH_N, 3HCDH, ECH_1, ECH_2
807 amino acids: PaperBLAST, CDD, Compare to cluster

FADN_BACSU / O32178 Probable 3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35 from Bacillus subtilis (strain 168)
PFams: 3HCDH_N, 3HCDH, 3HCDH, ECH_1, ECH_2
789 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 8 651-658 amino acids (not heteromeric)

A4YDS4 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); short-chain-enoyl-CoA hydratase (EC 4.2.1.150) from Metallosphaera sedula
A4YDS4 crotonyl-CoA hydratase/(S)-3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.35; EC 4.2.1.150) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
PFams: 3HCDH_N, NAD_binding_2, 3HCDH, 3HCDH, ECH_1, ECH_2
651 amino acids: PaperBLAST, CDD, Compare to cluster

D3RXI4 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) from Ferroglobus placidus
PFams: 3HCDH_N, NAD_Gly3P_dh_N, NAD_binding_2, F420_oxidored, 3HCDH, 3HCDH, ECH_1, ECH_2
658 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/11 heteromeric)

b0517 ureidoglycolate dehydrogenase (EC 1.1.1.350) from Escherichia coli K-12 substr. MG1655
ALLD_ECOLI / P77555 Ureidoglycolate dehydrogenase (NAD(+)); EC 1.1.1.350 from Escherichia coli (strain K12)
P77555 ureidoglycolate dehydrogenase (NAD+) (EC 1.1.1.350) from Escherichia coli
P77555 ureidoglycolate dehydrogenase (EC 1.1.1.350) from Escherichia coli (strain K12)
PFams: Ldh_2
349 amino acids: PaperBLAST, CDD

Q72M90 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Leptospira interrogans serovar Copenhageni
PFams: 3HCDH_N, 3HCDH
436 amino acids: PaperBLAST, CDD

Q9SZB3 farnesol dehydrogenase (NAD+) (EC 1.1.1.354) from Arabidopsis thaliana
PFams: RmlD_sub_bind, Epimerase, NmrA, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_10, NAD_binding_4
344 amino acids: PaperBLAST, CDD

GEDH_CARLC / B2NI93 Geraniol dehydrogenase; GeDH; Farnesol dehydrogenase; NAD(+)-farnesol dehydrogenase; EC 1.1.1.347; EC 1.1.1.354 from Carpoglyphus lactis (Dried fruit mite) (Acarus lactis)
B2NI93 geraniol dehydrogenase (NAD+) (EC 1.1.1.347) from Carpoglyphus lactis
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
378 amino acids: PaperBLAST, CDD

VRDA_ASPPA / B9WYE6 Versiconal hemiacetal acetate reductase; VHA reductase; EC 1.1.1.353 from Aspergillus parasiticus
B9WYE6 versiconal hemiacetal acetate reductase (EC 1.1.1.353) from Aspergillus parasiticus
PFams: Aldo_ket_red
343 amino acids: PaperBLAST, CDD

COLC_YERPU / G4WJD3 GDP-L-colitose synthase; EC 1.1.1.356 from Yersinia pseudotuberculosis
PFams: RmlD_sub_bind, Epimerase, GDP_Man_Dehyd
308 amino acids: PaperBLAST, CDD

ADHA_DOTSN / M2YJK1 5'-hydroxyaverantin dehydrogenase; HAVN dehydrogenase; Dothistromin biosynthesis protein adhA; EC 1.1.1.352 from Dothistroma septosporum (strain NZE10 / CBS 128990) (Red band needle blight fungus) (Mycosphaerella pini)
PFams: adh_short, adh_short_C2
306 amino acids: PaperBLAST, CDD
(similar to SwissProt::P87017 from Cluster 4, but similarity to seed sequence is below thresholds)

b1395 3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.35) from Escherichia coli K-12 substr. MG1655
PAAH_ECOLI / P76083 3-hydroxyadipyl-CoA dehydrogenase; EC 1.1.1.- from Escherichia coli (strain K12)
P76083 3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.35) from Escherichia coli (strain K12)
PFams: 3HCDH_N, NAD_binding_2, 3HCDH, 3HCDH_RFF, 3HCDH
475 amino acids: PaperBLAST, CDD

DIDH_COMTE / P80702 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase; 3-alpha-HSD; 3-alpha-hydroxysteroid dehydrogenase/3-oxosteroid reductase; HSD28; Hydroxyprostaglandin dehydrogenase; EC 1.1.1.50 from Comamonas testosteroni (Pseudomonas testosteroni)
P80702 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) from Comamonas testosteroni
P80702 3α-hydroxysteroid dehydrogenase/carbonyl reductase monomer (EC 1.1.1.50) from Comamonas testosteroni
PFams: adh_short, adh_short_C2
257 amino acids: PaperBLAST, CDD

KANK_STRKN / Q2MFU6 2'-dehydrokanamycin reductase; Kanamycin biosynthesis protein K; EC 1.1.1.355 from Streptomyces kanamyceticus
Q2MFU6 2'-dehydrokanamycin reductase (EC 1.1.1.355) from Streptomyces kanamyceticus
Q2MFU6 2'-oxokanamycin reductase (EC 1.1.1.355) from Streptomyces kanamyceticus
PFams: RmlD_sub_bind, Epimerase, NAD_binding_10
352 amino acids: PaperBLAST, CDD

MFEA_DICDI / Q9NKW1 Peroxisomal multifunctional enzyme A; MFE-A; MFE-1; EC 1.1.1.35 from Dictyostelium discoideum (Slime mold)
PFams: adh_short, KR, adh_short_C2, SCP2
441 amino acids: PaperBLAST, CDD