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Clusters of Characterized Proteins

Searching for 2.1.1.13

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Found 28 characterized proteins with matching descriptions. 3 of these are heteromeric.

Fetched 28 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 15 of these sequences

Found 4 clusters of similar sequences. Another 13 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 283-400 amino acids (not heteromeric)

ARSM_PSEA4 / U2ZU49 Arsenite methyltransferase; EC 2.1.1.137 from Pseudomonas alcaligenes (strain ATCC 14909 / DSM 50342 / JCM 20561 / NBRC 14159 / NCIMB 9945 / NCTC 10367 / 1577)
U2ZU49 arsenite methyltransferase (EC 2.1.1.137) from Pseudomonas alcaligenes
PFams: PCMT, Ubie_methyltran, Methyltransf_31, Methyltransf_23, Methyltransf_25, Methyltransf_11, Methyltransf_12, Methyltransf_8
346 amino acids: PaperBLAST, CDD, Compare to cluster

C0JV69 arsenite methyltransferase (EC 2.1.1.137) from Cyanidioschyzon sp.
PFams: Ubie_methyltran, Methyltransf_23, PCMT, Methyltransf_31, Methyltransf_25, Methyltransf_11, Methyltransf_12, Methyltransf_8
400 amino acids: PaperBLAST, CDD, Compare to cluster

Q58DQ0 arsenite methyltransferase (EC 2.1.1.137) from Bos taurus
PFams: Methyltransf_31, PCMT, Ubie_methyltran, Methyltransf_23, Methyltransf_25, Methyltransf_11, Methyltransf_12
374 amino acids: PaperBLAST, CDD, Compare to cluster

AS3MT_RAT / Q8VHT6 Arsenite methyltransferase; Methylarsonite methyltransferase; S-adenosyl-L-methionine:arsenic(III) methyltransferase; EC 2.1.1.137 from Rattus norvegicus (Rat)
Q8VHT6 arsenite methyltransferase (EC 2.1.1.137) from Rattus norvegicus
PFams: Methyltransf_23, Methyltransf_31, Ubie_methyltran, PCMT, Methyltransf_25, Methyltransf_11, Methyltransf_12
369 amino acids: PaperBLAST, CDD, Compare to cluster

Q91WU5 arsenite methyltransferase (EC 2.1.1.137) from Mus musculus
PFams: Methyltransf_23, Ubie_methyltran, Methyltransf_31, PCMT, PrmA, Methyltransf_25, Methyltransf_11, Methyltransf_12
376 amino acids: PaperBLAST, CDD, Compare to cluster

Q9HBK9 arsenic methyltransferase (EC 2.1.1.137) from Homo sapiens
AS3MT_HUMAN / Q9HBK9 Arsenite methyltransferase; Methylarsonite methyltransferase; S-adenosyl-L-methionine:arsenic(III) methyltransferase; EC 2.1.1.137 from Homo sapiens (Human)
Q9HBK9 arsenite methyltransferase (EC 2.1.1.137) from Homo sapiens
PFams: Methyltransf_31, PCMT, Ubie_methyltran, Methyltransf_23, Methyltransf_25, Methyltransf_11, Methyltransf_12, Methyltransf_8
375 amino acids: PaperBLAST, CDD, Compare to cluster

ARSM_RHOPA / Q6N3Y0 Arsenite methyltransferase; As(III) AdoMet methyltransferase; EC 2.1.1.137 from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
PFams: PCMT, Methyltransf_23, PrmA, Ubie_methyltran, MTS, Methyltransf_31, Methyltransf_25, Methyltransf_11, Methyltransf_12, UPF0020, Methyltransf_8
283 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 1221-1265 amino acids (not heteromeric)

b4019 cobalamin-dependent methionine synthase (EC 2.1.1.13) from Escherichia coli K-12 substr. MG1655
P13009 cobalamin-dependent methionine synthase (EC 2.1.1.13) from Escherichia coli (strain K12)
METH_ECOLI / P13009 Methionine synthase; 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12-dependent; MS; EC 2.1.1.13 from Escherichia coli (strain K12)
P13009 methionine synthase (EC 2.1.1.13) from Escherichia coli
CH_090726 methionine synthase; EC 2.1.1.13 from Escherichia coli K12
PFams: S-methyl_trans, Pterin_bind, B12-binding_2, B12-binding, Met_synt_B12
1227 amino acids: PaperBLAST, CDD, Compare to cluster

Q9Z2Q4 methionine synthase (EC 2.1.1.13) from Rattus norvegicus
PFams: S-methyl_trans, Pterin_bind, B12-binding_2, B12-binding, Met_synt_B12
1253 amino acids: PaperBLAST, CDD, Compare to cluster

Q99707 methionine synthase (EC 2.1.1.13) from Homo sapiens
METH_HUMAN / Q99707 Methionine synthase; 5-methyltetrahydrofolate--homocysteine methyltransferase; Vitamin-B12 dependent methionine synthase; MS; EC 2.1.1.13 from Homo sapiens (Human)
PFams: S-methyl_trans, Pterin_bind, B12-binding_2, B12-binding, Met_synt_B12
1265 amino acids: PaperBLAST, CDD, Compare to cluster

Q8NQD1 cob(I)alamin-dependent methionine synthase (EC 2.1.1.13) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: S-methyl_trans, Pterin_bind, B12-binding_2, B12-binding, Met_synt_B12
1221 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 249-270 amino acids (not heteromeric)

ARSM_METAC / Q8TJK1 Arsenite methyltransferase; As(III) methyltransferase; EC 2.1.1.137 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
PFams: Methyltransf_23, PCMT, CMAS, PrmA, Ubie_methyltran, Methyltransf_31, MTS, Methyltransf_25, Methyltransf_11, Methyltransf_12, UPF0020, Methyltransf_8
249 amino acids: PaperBLAST, CDD, Compare to cluster

ARSM_CLOSP / A0A0D3MJQ5 Arsenite methyltransferase; EC 2.1.1.137 from Clostridium sp.
A0A0D3MJQ5 arsenite methyltransferase (EC 2.1.1.137) from Clostridium sp.
PFams: PCMT, Ubie_methyltran, Methyltransf_23, MTS, PrmA, Methyltransf_31, Methyltransf_25, Methyltransf_11, Methyltransf_12, Methyltransf_8
270 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 242-254 amino acids (not heteromeric)

Q9R9K1 precorrin-3B C17-methyltransferase (EC 2.1.1.131) from Paracoccus denitrificans
PFams: TP_methylase
242 amino acids: PaperBLAST, CDD, Compare to cluster

P21640 precorrin-3B (C17)-methyltransferase (EC 2.1.1.131) from Sinorhizobium sp.
PFams: TP_methylase
254 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (3/13 heteromeric)

Q9WYA5 methionine synthase (EC 2.1.1.13) from Thermotoga maritima
PFams: S-methyl_trans, Pterin_bind, B12-binding_2, B12-binding
768 amino acids: PaperBLAST, CDD

P21921 precorrin-6B (C5,15) methyltransferase subunit (EC 2.1.1.132) from Sinorhizobium sp.
GI|151177 precorrin-6Y C(5,15)-methyltransferase (decarboxylating); EC 2.1.1.132 from Pseudomonas denitrificans
PFams: TP_methylase
413 amino acids: PaperBLAST, CDD

CMT1_TRILO / D3H5H5 Chlorophenol O-methyltransferase; COMPT; EC 2.1.1.136 from Trichoderma longibrachiatum
PFams: Methyltransf_2
467 amino acids: PaperBLAST, CDD

ARSM_HALSA / O52025 Arsenite methyltransferase; EC 2.1.1.137 from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
PFams: Ubie_methyltran, CMAS, Methyltransf_23, PCMT, PrmA, MTS, Methyltransf_31, Methyltransf_25, Methyltransf_11, Methyltransf_12
391 amino acids: PaperBLAST, CDD

P55299 methionine synthase (EC 2.1.1.13) from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)
METE_METTM / P55299 Methionine synthase; Homocysteine methyltransferase; Methylcobalamin:homocysteine methyltransferase; EC 2.1.1.- from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum)
PFams: Meth_synt_2, Meth_synt_1
309 amino acids: PaperBLAST, CDD

Q83WF7 3'-O-demethyl-staurosporine methyltransferase (EC 2.1.1.139) from Streptomyces sp. TP-A0274
PFams: CMAS, Methyltransf_29, MTS, Methyltransf_23, Ubie_methyltran, Methyltransf_31, Methyltransf_25, Methyltransf_11, Methyltransf_12
280 amino acids: PaperBLAST, CDD

P21639 CobI (EC 2.1.1.130) from Sinorhizobium sp.
PFams: TP_methylase
245 amino acids: PaperBLAST, CDD

P21922 precorrin-4 (C11)-methyltransferase (EC 2.1.1.133) from Sinorhizobium sp.
PFams: TP_methylase
253 amino acids: PaperBLAST, CDD

PGA1_c13340 Accessory protein for co(II)balamin reduction (DUF1638) (EC:2.1.1.13) from Phaeobacter inhibens BS107
PFams: DUF1638
241 amino acids: PaperBLAST, CDD

PGA1_c13350 Methionine synthase component, B12 binding and B12-binding cap domains (EC:2.1.1.13) from Phaeobacter inhibens BS107
PFams: B12-binding_2, B12-binding
Heteromeric, 233 amino acids: PaperBLAST, CDD

PGA1_c13370 Methionine synthase component, methyltransferase domain (EC:2.1.1.13) from Phaeobacter inhibens BS107
PFams: S-methyl_trans
Heteromeric, 338 amino acids: PaperBLAST, CDD

PGA1_c15200 ATP-dependent reduction of co(II)balamin (RamA-like) (EC:2.1.1.13) from Phaeobacter inhibens BS107
PFams: RACo_linker, Raco_middle, RACo_C_ter
698 amino acids: PaperBLAST, CDD

PGA1_c16040 Methionine synthase component, pterin-binding domain (EC:2.1.1.13) from Phaeobacter inhibens BS107
PFams: Pterin_bind, CdhD
Heteromeric, 353 amino acids: PaperBLAST, CDD