PaperBLAST – Find papers about a protein or its homologs

 

Clusters of Characterized Proteins

Searching for 2.1.1.13 as complete word(s)

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Found 11 characterized proteins with matching descriptions. 3 of these are heteromeric.

Fetched 11 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 4 of these sequences

Found 1 clusters of similar sequences. Another 7 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 1221-1265 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

b4019 cobalamin-dependent methionine synthase (EC 2.1.1.13) from Escherichia coli K-12 substr. MG1655
P13009 cobalamin-dependent methionine synthase (EC 2.1.1.13) from Escherichia coli (strain K12)
METH_ECOLI / P13009 Methionine synthase; 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12-dependent; MS; EC 2.1.1.13 from Escherichia coli (strain K12)
P13009 methionine synthase (EC 2.1.1.13) from Escherichia coli
CH_090726 methionine synthase; EC 2.1.1.13 from Escherichia coli K12
PFams: S-methyl_trans, Pterin_bind, B12-binding_2, B12-binding, Met_synt_B12
1227 amino acids: PaperBLAST, CDD, Compare to cluster

Q9Z2Q4 methionine synthase (EC 2.1.1.13) from Rattus norvegicus
PFams: S-methyl_trans, Pterin_bind, B12-binding_2, B12-binding, Met_synt_B12
1253 amino acids: PaperBLAST, CDD, Compare to cluster

Q99707 methionine synthase (EC 2.1.1.13) from Homo sapiens
METH_HUMAN / Q99707 Methionine synthase; 5-methyltetrahydrofolate--homocysteine methyltransferase; Vitamin-B12 dependent methionine synthase; MS; EC 2.1.1.13 from Homo sapiens (Human)
PFams: S-methyl_trans, Pterin_bind, B12-binding_2, B12-binding, Met_synt_B12
1265 amino acids: PaperBLAST, CDD, Compare to cluster

Q8NQD1 cob(I)alamin-dependent methionine synthase (EC 2.1.1.13) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: S-methyl_trans, Pterin_bind, B12-binding_2, B12-binding, Met_synt_B12
1221 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (3/7 heteromeric)

Q9WYA5 methionine synthase (EC 2.1.1.13) from Thermotoga maritima
PFams: S-methyl_trans, Pterin_bind, B12-binding_2, B12-binding
768 amino acids: PaperBLAST, CDD

P55299 methionine synthase (EC 2.1.1.13) from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)
METE_METTM / P55299 Methionine synthase; Homocysteine methyltransferase; Methylcobalamin:homocysteine methyltransferase; EC 2.1.1.- from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum)
PFams: Meth_synt_2, Meth_synt_1
309 amino acids: PaperBLAST, CDD

PGA1_c13340 Accessory protein for co(II)balamin reduction (DUF1638) (EC:2.1.1.13) from Phaeobacter inhibens BS107
PFams: DUF1638
241 amino acids: PaperBLAST, CDD

PGA1_c13350 Methionine synthase component, B12 binding and B12-binding cap domains (EC:2.1.1.13) from Phaeobacter inhibens BS107
PFams: B12-binding_2, B12-binding
Heteromeric, 233 amino acids: PaperBLAST, CDD

PGA1_c13370 Methionine synthase component, methyltransferase domain (EC:2.1.1.13) from Phaeobacter inhibens BS107
PFams: S-methyl_trans
Heteromeric, 338 amino acids: PaperBLAST, CDD

PGA1_c15200 ATP-dependent reduction of co(II)balamin (RamA-like) (EC:2.1.1.13) from Phaeobacter inhibens BS107
PFams: RACo_linker, Raco_middle, RACo_C_ter
698 amino acids: PaperBLAST, CDD

PGA1_c16040 Methionine synthase component, pterin-binding domain (EC:2.1.1.13) from Phaeobacter inhibens BS107
PFams: Pterin_bind, CdhD
Heteromeric, 353 amino acids: PaperBLAST, CDD