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Clusters of Characterized Proteins

Searching for 2.3.1.29

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Found 23 characterized proteins with matching descriptions. 3 of these are heteromeric.

Fetched 23 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 20 of these sequences

Found 5 clusters of similar sequences. Another 3 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 395-419 amino acids (not heteromeric)

b3617 2-amino-3-ketobutyrate CoA ligase (EC 2.3.1.29) from Escherichia coli K-12 substr. MG1655
KBL_ECOLI / P0AB77 2-amino-3-ketobutyrate coenzyme A ligase; AKB ligase; Glycine acetyltransferase; EC 2.3.1.29 from Escherichia coli (strain K12)
P0AB77 glycine C-acetyltransferase (EC 2.3.1.29) from Escherichia coli
P0AB77 2-amino-3-ketobutyrate CoA ligase (EC 2.3.1.29) from Escherichia coli (strain K12)
CH_088327 2-amino-3-ketobutyrate coenzyme A ligase; EC 2.3.1.29 from Escherichia coli K12
PFams: Aminotran_1_2
398 amino acids: PaperBLAST, CDD, Compare to cluster

KBL_HUMAN / O75600 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; AKB ligase; Aminoacetone synthase; Glycine acetyltransferase; EC 2.3.1.29 from Homo sapiens (Human)
O75600 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) from Homo sapiens
PFams: Aminotran_1_2, Aminotran_5
419 amino acids: PaperBLAST, CDD, Compare to cluster

KBL_MOUSE / O88986 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; AKB ligase; Aminoacetone synthase; Glycine acetyltransferase; EC 2.3.1.29 from Mus musculus (Mouse)
PFams: Aminotran_1_2, Aminotran_5
416 amino acids: PaperBLAST, CDD, Compare to cluster

KBL_BOVIN / Q0P5L8 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; AKB ligase; Aminoacetone synthase; Glycine acetyltransferase; EC 2.3.1.29 from Bos taurus (Bovine)
PFams: Aminotran_1_2, Aminotran_5
419 amino acids: PaperBLAST, CDD, Compare to cluster

BIKB_THET8 / Q5SHZ8 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase; AONS/AKB ligase; 7-keto-8-amino-pelargonic acid synthase; 7-KAP synthase; KAPA synthase; 8-amino-7-ketopelargonate synthase; Alpha-oxoamine synthase; Glycine acetyltransferase; EC 2.3.1.29; EC 2.3.1.47 from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
PFams: Aminotran_1_2, Aminotran_5, Cys_Met_Meta_PP
395 amino acids: PaperBLAST, CDD, Compare to cluster

Shewana3_4104 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) from Shewanella sp. ANA-3
PFams: Aminotran_1_2
397 amino acids: PaperBLAST, CDD, Compare to cluster

RR42_RS28295 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) from Cupriavidus basilensis 4G11
PFams: Aminotran_1_2
400 amino acids: PaperBLAST, CDD, Compare to cluster

BWI76_RS27255 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) from Klebsiella michiganensis M5al
PFams: Aminotran_1_2
397 amino acids: PaperBLAST, CDD, Compare to cluster

PGA1_c34330 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) from Phaeobacter inhibens BS107
PFams: Aminotran_1_2
395 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 380-392 amino acids (not heteromeric)

CERS5_HUMAN / Q8N5B7 Ceramide synthase 5; CerS5; LAG1 longevity assurance homolog 5; Sphingosine N-acyltransferase CERS5; EC 2.3.1.-; EC 2.3.1.24 from Homo sapiens (Human)
Q8N5B7 sphingosine N-acyltransferase (EC 2.3.1.24) from Homo sapiens
Q8N5B7 ceramide synthase 5 (EC 2.3.1.291) from Homo sapiens
PFams: Homeodomain, TRAM_LAG1_CLN8
392 amino acids: PaperBLAST, CDD, Compare to cluster

CERS2_HUMAN / Q96G23 Ceramide synthase 2; CerS2; LAG1 longevity assurance homolog 2; SP260; Sphingosine N-acyltransferase CERS2; Tumor metastasis-suppressor gene 1 protein; EC 2.3.1.-; EC 2.3.1.24 from Homo sapiens (Human)
Q96G23 sphingosine N-acyltransferase (EC 2.3.1.24) from Homo sapiens
Q96G23 ceramide synthase 2 (EC 2.3.1.297) from Homo sapiens
PFams: Homeodomain, TRAM_LAG1_CLN8
380 amino acids: PaperBLAST, CDD, Compare to cluster

CERS6_HUMAN / Q6ZMG9 Ceramide synthase 6; CerS6; LAG1 longevity assurance homolog 6; EC 2.3.1.- from Homo sapiens (Human)
Q6ZMG9 sphingosine N-acyltransferase (EC 2.3.1.24) from Homo sapiens
Q6ZMG9 ceramide synthase 6 (EC 2.3.1.24; EC 2.3.1.291) from Homo sapiens
PFams: Homeodomain, TRAM_LAG1_CLN8
384 amino acids: PaperBLAST, CDD, Compare to cluster

CERS3_HUMAN / Q8IU89 Ceramide synthase 3; CerS3; Dihydroceramide synthase 3; LAG1 longevity assurance homolog 3; Sphingosine N-acyltransferase CERS3; EC 2.3.1.-; EC 2.3.1.24 from Homo sapiens (Human)
Q8IU89 ceramide synthase 3 (EC 2.3.1.298; EC 2.3.1.297) from Homo sapiens
PFams: Homeodomain, TRAM_LAG1_CLN8
383 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 296-310 amino acids (not heteromeric)

Q9LJK3 ceramide synthase 2 (EC 2.3.1.291) from Arabidopsis thaliana
PFams: TRAM_LAG1_CLN8
296 amino acids: PaperBLAST, CDD, Compare to cluster

Q9LDF2 ceramide synthase 1 (EC 2.3.1.297) from Arabidopsis thaliana
PFams: TRAM_LAG1_CLN8
310 amino acids: PaperBLAST, CDD, Compare to cluster

Q6NQI8 ceramide synthase 3 (EC 2.3.1.297) from Arabidopsis thaliana
PFams: TRAM_LAG1_CLN8
308 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 416-417 amino acids (not heteromeric)

FAB1_MYCTE / H8ESN0 3-oxoacyl-[acyl-carrier-protein] synthase 1; Beta-ketoacyl-ACP synthase 1; KAS 1; EC 2.3.1.41 from Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
FAB1_MYCTU / P9WQD9 3-oxoacyl-[acyl-carrier-protein] synthase 1; Beta-ketoacyl-ACP synthase 1; KAS 1; EC 2.3.1.41 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WQD9 beta-ketoacyl-[acyl-carrier-protein] synthase I (EC 2.3.1.41) from Mycobacterium tuberculosis
P9WQD9 meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I monomer (EC 2.3.1.293) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: ketoacyl-synt, Thiolase_N, Ketoacyl-synt_C
416 amino acids: PaperBLAST, CDD, Compare to cluster

FAB2_MYCTU / P9WQD7 3-oxoacyl-[acyl-carrier-protein] synthase 2; Beta-ketoacyl-ACP synthase 2; KAS 2; EC 2.3.1.41 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WQD7 meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II (EC 2.3.1.294) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: ketoacyl-synt, Thiolase_N, Ketoacyl-synt_C
417 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 411-418 amino acids (heteromeric)

LAC1_YEAST / P28496 Ceramide synthase LAC1; Sphingosine N-acyltransferase LAC1; EC 2.3.1.-; EC 2.3.1.24 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
A6ZZV7 sphingosine N-acyltransferase (EC 2.3.1.24) from Saccharomyces cerevisiae
P28496 ceramide synthase LAC1 component (EC 2.3.1.297) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
PFams: TRAM1, TRAM_LAG1_CLN8
Heteromeric, 418 amino acids: PaperBLAST, CDD, Compare to cluster

LAG1_YEAST / P38703 Ceramide synthase LAG1; Longevity assurance factor 1; Longevity assurance gene 1 protein; Longevity assurance protein 1; Sphingosine N-acyltransferase LAG1; EC 2.3.1.-; EC 2.3.1.24 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P38703 ceramide synthase LAG1 component (EC 2.3.1.297) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
PFams: TRAM1, TRAM_LAG1_CLN8
Heteromeric, 411 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (1/3 heteromeric)

LIP1_YEAST / Q03579 Ceramide synthase subunit LIP1; LAG1/LAC1-interacting protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Q03579 ceramide synthase LIP1 component (EC 2.3.1.297) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Heteromeric, 150 amino acids: PaperBLAST, CDD

PLPL1_HUMAN / Q8N8W4 Patatin-like phospholipase domain-containing protein 1; EC 3.1.1.- from Homo sapiens (Human)
Q8N8W4 ω-hydroxyceramide transacylase (EC 2.3.1.296) from Homo sapiens
PFams: Patatin
532 amino acids: PaperBLAST, CDD

I6XD69 mycoketide-CoA synthase monomer (EC 2.3.1.295) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: ketoacyl-synt, Ketoacyl-synt_C, KAsynt_C_assoc, Acyl_transf_1, PS-DH, ADH_N, ADH_zinc_N, ADH_zinc_N_2, KR, adh_short, Epimerase, PP-binding, ketoacyl-synt, Ketoacyl-synt_C, KAsynt_C_assoc, Acyl_transf_1, PS-DH, ADH_zinc_N, ADH_zinc_N_2, KR, adh_short, Epimerase, PP-binding
4151 amino acids: PaperBLAST, CDD