Searching for 4.1.3.4
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Found 33 characterized proteins with matching descriptions. 1 of these are heteromeric.
Fetched 33 sequences
Running BLASTp
Found similarities, at above 30% identity and 75% coverage, for 23 of these sequences
Found 5 clusters of similar sequences. Another 10 sequences are not clustered. Download as table or as draft rules or view by organism
P35914 Hydroxymethylglutaryl-CoA lyase, mitochondrial (EC 4.1.3.4) from Homo sapiens
HMGCL_HUMAN / P35914 Hydroxymethylglutaryl-CoA lyase, mitochondrial; HL; HMG-CoA lyase; 3-hydroxy-3-methylglutarate-CoA lyase; EC 4.1.3.4 from Homo sapiens (Human)
P35914 hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) from Homo sapiens
PFams: HMGL-like
325 amino acids: PaperBLAST, CDD, Compare to cluster
HMGCL_RAT / P97519 Hydroxymethylglutaryl-CoA lyase, mitochondrial; HL; HMG-CoA lyase; 3-hydroxy-3-methylglutarate-CoA lyase; EC 4.1.3.4 from Rattus norvegicus (Rat)
P97519 hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) from Rattus norvegicus
PFams: HMGL-like
325 amino acids: PaperBLAST, CDD, Compare to cluster
Q9I2A0 hydroxymethylglutaryl-CoA lyase subunit (EC 4.1.3.26; EC 4.1.3.4) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
LIUE_PSEAE / Q9I2A0 3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy-methylglutaryl-CoA lyase; HIHG-CoA lyase; HMG-CoA lyase; (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase; 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase; EC 4.1.3.26; EC 4.1.3.4 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9I2A0 3-Hydroxy-3-isohexenylglutaryl-CoA lyase (EC 4.1.3.26) from Pseudomonas aeruginosa PAO1
PFams: HMGL-like
300 amino acids: PaperBLAST, CDD, Compare to cluster
P13703 hydroxymethylglutaryl-CoA lyase monomer (EC 4.1.3.4) from Pseudomonas mevalonii
GB|AAA25895.1 hydroxymethylglutaryl-CoA lyase; EC 4.1.3.4 from Pseudomonas mevalonii
PFams: HMGL-like
301 amino acids: PaperBLAST, CDD, Compare to cluster
CCL_CHLAA / A9WGE2 (R)-citramalyl-CoA lyase; EC 4.1.3.46 from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
PFams: HMGL-like
317 amino acids: PaperBLAST, CDD, Compare to cluster
HMGC2_RAT / D4A5C3 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic; 3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1; EC 4.1.3.4 from Rattus norvegicus (Rat)
PFams: HMGL-like
343 amino acids: PaperBLAST, CDD, Compare to cluster
HMGCL_BACSU / O34873 Hydroxymethylglutaryl-CoA lyase YngG; HL; HMG-CoA lyase; 3-hydroxy-3-methylglutarate-CoA lyase; EC 4.1.3.4 from Bacillus subtilis (strain 168)
PFams: HMGL-like
299 amino acids: PaperBLAST, CDD, Compare to cluster
HMGCL_MOUSE / P38060 Hydroxymethylglutaryl-CoA lyase, mitochondrial; HL; HMG-CoA lyase; 3-hydroxy-3-methylglutarate-CoA lyase; EC 4.1.3.4 from Mus musculus (Mouse)
PFams: HMGL-like
325 amino acids: PaperBLAST, CDD, Compare to cluster
HMGC2_HUMAN / Q8TB92 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic; 3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1; Endoplasmic reticulum 3-hydroxy-3-methylglutaryl-CoA lyase; er-cHL; EC 4.1.3.4 from Homo sapiens (Human)
PFams: HMGL-like
370 amino acids: PaperBLAST, CDD, Compare to cluster
CA265_RS13115 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) from Pedobacter sp. GW460-11-11-14-LB5
PFams: HMGL-like
286 amino acids: PaperBLAST, CDD, Compare to cluster
SM_b21125 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) from Sinorhizobium meliloti 1021
PFams: HMGL-like
289 amino acids: PaperBLAST, CDD, Compare to cluster
HOA4_PARXL / P51015 4-hydroxy-2-oxovalerate aldolase 4; HOA 4; 4-hydroxy-2-keto-pentanoic acid aldolase 4; 4-hydroxy-2-oxohexanoate aldolase; 4-hydroxy-2-oxopentanoate aldolase 4; EC 4.1.3.39; EC 4.1.3.43 from Paraburkholderia xenovorans (strain LB400)
P51015 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.39); 4-hydroxy-2-oxohexanoate aldolase (EC 4.1.3.43) from Paraburkholderia xenovorans LB400
GB|ABE37049.1 4-hydroxy-2-oxovalerate aldolase; EC 4.1.3.39 from Burkholderia xenovorans LB400
PFams: HMGL-like, DmpG_comm
Heteromeric, 346 amino acids: PaperBLAST, CDD, Compare to cluster
P9WMK5 4-hydroxy-2-oxohexanoate aldolase monomer (EC 4.1.3.43) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WMK5 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.39) from Mycobacterium tuberculosis
PFams: HMGL-like, DmpG_comm
346 amino acids: PaperBLAST, CDD, Compare to cluster
HOA_THET8 / Q53WI0 4-hydroxy-2-oxovalerate aldolase; HOA; 4-hydroxy-2-keto-pentanoic acid aldolase; 4-hydroxy-2-oxohexanoate aldolase; 4-hydroxy-2-oxopentanoate aldolase; EC 4.1.3.39; EC 4.1.3.43 from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Q53WI0 4-hydroxy-2-oxohexanoate aldolase (EC 4.1.3.43) from Thermus thermophilus
PFams: HMGL-like, DmpG_comm
347 amino acids: PaperBLAST, CDD, Compare to cluster
Q0S815 4-hydroxy-2-oxohexanoate aldolase (EC 4.1.3.43) from Rhodococcus jostii (strain RHA1)
PFams: HMGL-like, DmpG_comm
339 amino acids: PaperBLAST, CDD, Compare to cluster
Q83VZ3 4-hydroxy-2-oxohexanoate aldolase (EC 4.1.3.43) from Comamonas testosteroni
PFams: HMGL-like, DmpG_comm
350 amino acids: PaperBLAST, CDD, Compare to cluster
O59412 tRNA-4-demethylwyosine synthase (EC 4.1.3.44) from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
TYW1_PYRHO / O59412 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; tRNA wyosine derivatives biosynthesis protein Taw1; EC 4.1.3.44 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
O59412 tRNA 4-demethylwyosine synthase (AdoMet-dependent) (EC 4.1.3.44) from Pyrococcus horikoshii
GB|BAA30819.1 wye-base biosynthesis protein TYW1 from Pyrococcus horikoshii OT3
PFams: Radical_SAM, Wyosine_form
342 amino acids: PaperBLAST, CDD, Compare to cluster
TYW1_METJA / Q57705 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; MjTYW1; tRNA wyosine derivatives biosynthesis protein Taw1; EC 4.1.3.44 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Q57705 tRNA 4-demethylwyosine synthase (AdoMet-dependent) (EC 4.1.3.44) from Methanocaldococcus jannaschii
GB|AAB98244.1 wyosine biosynthesis protein TYW1 from Methanocaldococcus jannaschii DSM 2661
PFams: Radical_SAM, Wyosine_form
311 amino acids: PaperBLAST, CDD, Compare to cluster
TYW1_PYRAB / Q9V1F9 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; tRNA wyosine derivatives biosynthesis protein Taw1; EC 4.1.3.44 from Pyrococcus abyssi (strain GE5 / Orsay)
Q9V1F9 tRNA 4-demethylwyosine synthase (AdoMet-dependent) (EC 4.1.3.44) from Pyrococcus abyssi
PFams: Radical_SAM, Wyosine_form
342 amino acids: PaperBLAST, CDD, Compare to cluster
BHCC_PARDP / A1B8Z1 3-hydroxy-D-aspartate aldolase; beta-hydroxyaspartate aldolase; EC 4.1.3.41 from Paracoccus denitrificans (strain Pd 1222)
PFams: Ala_racemase_N, D-ser_dehydrat
387 amino acids: PaperBLAST, CDD, Compare to cluster
Q8GRC8 D 3-hydroxyaspartate aldolase monomer (EC 4.1.3.41) from Paracoccus denitrificans
BHCC_PARDE / Q8GRC8 3-hydroxy-D-aspartate aldolase; D-3-hydroxyaspartate aldolase; D-HAA; EC 4.1.3.41 from Paracoccus denitrificans
Q8GRC8 3-hydroxy-D-aspartate aldolase (EC 4.1.3.41) from Paracoccus denitrificans
PFams: Ala_racemase_N, D-ser_dehydrat
387 amino acids: PaperBLAST, CDD, Compare to cluster
V4HSG8 chorismate lyase (EC 4.1.3.40) from Pseudoalteromonas luteoviolacea 2ta16
PFams: DUF98
202 amino acids: PaperBLAST, CDD, Compare to cluster
A0A1S6M1P0 chorismate lyase (EC 4.1.3.40) from Hormoscilla spongeliae SP12
PFams: DUF98
192 amino acids: PaperBLAST, CDD, Compare to cluster
A0A172MLA1 (S)-citramalyl-CoA lyase (EC 4.1.3.25); (R)-citramalyl-CoA lyase (EC 4.1.3.46) from Aspergillus terreus
PFams: HpcH_HpaI
322 amino acids: PaperBLAST, CDD
HYG5_STRHY / O30478 3-hydroxybenzoate synthase; EC 4.1.3.45 from Streptomyces hygroscopicus
O30478 3-hydroxybenzoate synthase (EC 4.1.3.45) from Streptomyces hygroscopicus
340 amino acids: PaperBLAST, CDD
b1850 KHG/KDPG aldolase (EC 4.1.2.55; EC 4.1.2.14; EC 4.1.3.42; EC 4.1.1.112) from Escherichia coli K-12 substr. MG1655
P0A955 KHG/KDPG aldolase (EC 4.1.2.55; EC 4.1.3.42; EC 4.1.1.112) from Escherichia coli (strain K12)
ALKH_ECOLI / P0A955 KHG/KDPG aldolase; EC 4.1.3.16; EC 4.1.2.14 from Escherichia coli (strain K12)
P0A955 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14); 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16); (4S)-4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.42) from Escherichia coli
RF|NP_416364 KHG/KDPG aldolase; EC 4.1.2.14; EC 4.1.3.16 from Escherichia coli K12
PFams: Aldolase
213 amino acids: PaperBLAST, CDD
b4039 chorismate lyase (EC 4.1.3.40) from Escherichia coli K-12 substr. MG1655
P26602 chorismate lyase (EC 4.1.3.40) from Escherichia coli (strain K12)
UBIC_ECOLI / P26602 Chorismate pyruvate-lyase; CL; CPL; EC 4.1.3.40 from Escherichia coli (strain K12)
P26602 chorismate lyase (EC 4.1.3.40) from Escherichia coli
PDB|1G1B_A chorismate lyase; EC 4.1.3.40 from Escherichia coli K12
PFams: Chor_lyase
165 amino acids: PaperBLAST, CDD
P73322 chorismate lyase (EC 4.1.3.40) from Synechocystis sp. (strain PCC 6803 / Kazusa)
P73322 chorismate lyase (EC 4.1.3.40) from Synechocystis sp.
PFams: DUF98
139 amino acids: PaperBLAST, CDD
Q08960 tRNA-4-demethylwyosine synthase (EC 4.1.3.44) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
TYW1_YEAST / Q08960 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; tRNA wybutosine-synthesizing protein 1; EC 4.1.3.44 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Q08960 tRNA 4-demethylwyosine synthase (AdoMet-dependent) (EC 4.1.3.44) from Saccharomyces cerevisiae
PFams: Flavodoxin_1, Radical_SAM, Wyosine_form
810 amino acids: PaperBLAST, CDD
CH_122457 3-hydroxy-3-methylglutaryl-coenzyme A lyase/3-methylglutaconyl-coenzyme A hydratase; EC 4.1.3.4; EC 4.2.1.18 from Emericella nidulans
PFams: HMGL-like, ECH_1, ECH_2
599 amino acids: PaperBLAST, CDD
HMGCL_ARATH / O81027 Hydroxymethylglutaryl-CoA lyase, mitochondrial; HL; HMG-CoA lyase; 3-hydroxy-3-methylglutarate-CoA lyase; EC 4.1.3.4 from Arabidopsis thaliana (Mouse-ear cress)
PFams: HMGL-like
468 amino acids: PaperBLAST, CDD
Q7TXK6 chorismate lyase (EC 4.1.3.40) from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
PHBS_MYCTU / P9WIC5 Chorismate pyruvate-lyase; 4-HB synthase; p-hydroxybenzoic acid synthase; EC 4.1.3.40 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: DUF98
199 amino acids: PaperBLAST, CDD
Q58217 chorismate lyase (EC 4.1.3.40) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
PFams: DUF98
184 amino acids: PaperBLAST, CDD