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Clusters of Characterized Proteins

Searching for 4.1.99.1

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Found 58 characterized proteins with matching descriptions. 8 of these are heteromeric.

Fetched 58 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 54 of these sequences

Found 12 clusters of similar sequences. Another 4 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 519-628 amino acids (not heteromeric)

A0A2Z5J5J9 (6-4)DNA photolyase (EC 4.1.99.13) from Chlamydomonas sp. ICE-L
PFams: DNA_photolyase, FAD_binding_7
559 amino acids: PaperBLAST, CDD, Compare to cluster

G0RI60 (6-4)DNA photolyase (EC 4.1.99.13) from Trichoderma reesei
PFams: DNA_photolyase, FAD_binding_7
628 amino acids: PaperBLAST, CDD, Compare to cluster

M1V623 (6-4)DNA photolyase (EC 4.1.99.13) from Cyanidioschyzon merolae
PFams: DNA_photolyase, FAD_binding_7
519 amino acids: PaperBLAST, CDD, Compare to cluster

O48652 (6-4)DNA photolyase (EC 4.1.99.13) from Arabidopsis thaliana
UVR3_ARATH / O48652 (6-4)DNA photolyase; Protein UV repair defective 3; EC 4.1.99.13 from Arabidopsis thaliana (Mouse-ear cress)
O48652 (6-4)DNA photolyase (EC 4.1.99.13) from Arabidopsis thaliana
PFams: DNA_photolyase, FAD_binding_7
556 amino acids: PaperBLAST, CDD, Compare to cluster

Q0E8P0 (6-4)DNA photolyase (EC 4.1.99.13) from Drosophila melanogaster
PFams: DNA_photolyase, FAD_binding_7
540 amino acids: PaperBLAST, CDD, Compare to cluster

Q52Z99 (6-4)DNA photolyase (EC 4.1.99.13) from Dunaliella salina
PFams: DNA_photolyase, FAD_binding_7
600 amino acids: PaperBLAST, CDD, Compare to cluster

Q5IFN1 (6-4)DNA photolyase (EC 4.1.99.13) from Ostreococcus tauri
PFams: DNA_photolyase, FAD_binding_7
559 amino acids: PaperBLAST, CDD, Compare to cluster

Q8SXK5 (6-4)DNA photolyase (EC 4.1.99.13) from Drosophila melanogaster
PFams: DNA_photolyase, FAD_binding_7
540 amino acids: PaperBLAST, CDD, Compare to cluster

Q9I910 (6-4)DNA photolyase (EC 4.1.99.13) from Xenopus laevis
PFams: DNA_photolyase, FAD_binding_7
526 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 202-233 amino acids (not heteromeric)

RIB3_CANAL / Q5A3V6 3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; EC 4.1.99.12 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Q5A3V6 3,4-dihydroxy-2-butanone-4-phosphate synthase (EC 4.1.99.12) from Candida albicans
PDB|2RIS_A 3,4-dihydroxy-2-butanone 4-phosphate synthase; EC 4.1.99.12 from Candida albicans
PFams: DHBP_synthase
204 amino acids: PaperBLAST, CDD, Compare to cluster

b3041 3,4-dihydroxy-2-butanone-4-phosphate synthase (EC 4.1.99.12) from Escherichia coli K-12 substr. MG1655
P0A7J0 3,4-dihydroxy-2-butanone-4-phosphate synthase (EC 4.1.99.12) from Escherichia coli (strain K12)
RIBB_ECOLI / P0A7J0 3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; EC 4.1.99.12 from Escherichia coli (strain K12)
P0A7J0 3,4-dihydroxy-2-butanone-4-phosphate synthase (EC 4.1.99.12) from Escherichia coli K-12
GB|AAN44559.1 3,4-dihydroxy-2-butanone 4-phosphate synthase; EC 4.1.99.12 from Shigella flexneri
PFams: DHBP_synthase
217 amino acids: PaperBLAST, CDD, Compare to cluster

P66032 3,4-dihydroxy-2-butanone-4-phosphate synthase (EC 4.1.99.12) from Salmonella enterica subsp. enterica serovar Typhimurium
PFams: DHBP_synthase
217 amino acids: PaperBLAST, CDD, Compare to cluster

Q9KKP2 3,4-dihydroxy-2-butanone-4-phosphate synthase (EC 4.1.99.12) from Vibrio cholerae serotype O1
PFams: DHBP_synthase
218 amino acids: PaperBLAST, CDD, Compare to cluster

Q60364 3,4-dihydroxy-2-butanone 4-phosphate synthase monomer (EC 4.1.99.12) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
RIBB_METJA / Q60364 3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; EC 4.1.99.12 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
PFams: DHBP_synthase
227 amino acids: PaperBLAST, CDD, Compare to cluster

RIB3_MAGO7 / Q8TG90 3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; EC 4.1.99.12 from Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)
PFams: DHBP_synthase
233 amino acids: PaperBLAST, CDD, Compare to cluster

RIB3_YEAST / Q99258 3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; EC 4.1.99.12 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: DHBP_synthase
208 amino acids: PaperBLAST, CDD, Compare to cluster

A5DHJ1 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) from Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)
PFams: DHBP_synthase
202 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 454-488 amino acids (not heteromeric)

A5EYI0 tryptophanase (EC 4.1.99.1) from Vibrio cholerae O1
PFams: Beta_elim_lyase
472 amino acids: PaperBLAST, CDD, Compare to cluster

E9RK37 tryptophanase (EC 4.1.99.1) from Prevotella intermedia
PFams: Beta_elim_lyase
458 amino acids: PaperBLAST, CDD, Compare to cluster

b3708 tryptophanase (EC 4.1.99.1; EC 4.4.1.1; EC 4.4.1.28) from Escherichia coli K-12 substr. MG1655
P0A853 tryptophanase (EC 4.1.99.1; EC 4.4.1.1) from Escherichia coli (strain K12)
TNAA_ECOLI / P0A853 Tryptophanase; L-tryptophan indole-lyase; TNase; EC 4.1.99.1 from Escherichia coli (strain K12)
P0A853 tryptophanase (EC 4.1.99.1) from Escherichia coli
RF|NP_418164 tryptophanase from Escherichia coli K12
PFams: Beta_elim_lyase
471 amino acids: PaperBLAST, CDD, Compare to cluster

P28796 tryptophanase (EC 4.1.99.1) from Proteus vulgaris
PFams: Beta_elim_lyase, Aminotran_1_2
467 amino acids: PaperBLAST, CDD, Compare to cluster

P31015 tryptophanase (EC 4.1.99.1) from Symbiobacterium thermophilum
PFams: Beta_elim_lyase
454 amino acids: PaperBLAST, CDD, Compare to cluster

Q6LP64 tryptophanase (EC 4.1.99.1) from Photobacterium profundum
PFams: Beta_elim_lyase
488 amino acids: PaperBLAST, CDD, Compare to cluster

BWI76_RS03535 Tryptophanase (EC 4.1.99.1) from Klebsiella michiganensis M5al
PFams: Beta_elim_lyase
462 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 590-650 amino acids (not heteromeric)

B9TU32 phosphomethylpyrimidine synthase (EC 4.1.99.17) from Solanum lycopersicum
PFams: ThiC_Rad_SAM
650 amino acids: PaperBLAST, CDD, Compare to cluster

O82392 phosphomethylpyrimidine synthase (EC 4.1.99.17) from Arabidopsis thaliana
THIC_ARATH / O82392 Phosphomethylpyrimidine synthase, chloroplastic; Hydroxymethylpyrimidine phosphate synthase; HMP-P synthase; HMP-phosphate synthase; HMPP synthase; Protein PYRIMIDINE REQUIRING; Thiamine biosynthesis protein ThiC; Protein THIAMINE C; EC 4.1.99.17 from Arabidopsis thaliana (Mouse-ear cress)
O82392 phosphomethylpyrimidine synthase (EC 4.1.99.17) from Arabidopsis thaliana
PFams: ThiC_Rad_SAM
644 amino acids: PaperBLAST, CDD, Compare to cluster

Q9A6Q5 HMP-P synthase monomer (EC 4.1.99.17) from Caulobacter vibrioides (strain ATCC 19089 / CB15)
THIC_CAUVC / Q9A6Q5 Phosphomethylpyrimidine synthase; Hydroxymethylpyrimidine phosphate synthase; HMP-P synthase; HMP-phosphate synthase; HMPP synthase; Thiamine biosynthesis protein ThiC; EC 4.1.99.17 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus)
Q9A6Q5 phosphomethylpyrimidine synthase (EC 4.1.99.17) from Caulobacter vibrioides
PFams: ThiC-associated, ThiC_Rad_SAM
612 amino acids: PaperBLAST, CDD, Compare to cluster

P45740 phosphomethylpyrimidine synthase monomer (EC 4.1.99.17) from Bacillus subtilis (strain 168)
THIC_BACSU / P45740 Phosphomethylpyrimidine synthase; Hydroxymethylpyrimidine phosphate synthase; HMP-P synthase; HMP-phosphate synthase; HMPP synthase; Thiamine biosynthesis protein ThiC; EC 4.1.99.17 from Bacillus subtilis (strain 168)
PFams: ThiC-associated, ThiC_Rad_SAM
590 amino acids: PaperBLAST, CDD, Compare to cluster

THIC_SALTY / Q9L9I7 Phosphomethylpyrimidine synthase; Hydroxymethylpyrimidine phosphate synthase; HMP-P synthase; HMP-phosphate synthase; HMPP synthase; Thiamine biosynthesis protein ThiC; EC 4.1.99.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q9L9I7 phosphomethylpyrimidine synthase (EC 4.1.99.17) from Salmonella enterica
PFams: ThiC-associated, ThiC_Rad_SAM
631 amino acids: PaperBLAST, CDD, Compare to cluster

b3994 phosphomethylpyrimidine synthase (EC 4.1.99.17) from Escherichia coli K-12 substr. MG1655
P30136 phosphomethylpyrimidine synthase (EC 4.1.99.17) from Escherichia coli (strain K12)
PFams: ThiC-associated, ThiC_Rad_SAM
631 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 861-864 amino acids (2/5 heteromeric)

I6LHT8 benzylsuccinate synthase (EC 4.1.99.11) from Azoarcus sp. CIB
PFams: PFL-like, Gly_radical
864 amino acids: PaperBLAST, CDD, Compare to cluster

O87943 benzylsuccinate synthase α subunit from Thauera aromatica
BSSA_THAAR / O87943 Benzylsuccinate synthase alpha subunit; EC 4.1.99.11 from Thauera aromatica
O87943 benzylsuccinate synthase (subunit 3/3) (EC 4.1.99.11) from Thauera aromatica
PFams: PFL-like, Gly_radical
Heteromeric, 861 amino acids: PaperBLAST, CDD, Compare to cluster

Q39VF1 benzylsuccinate synthase (EC 4.1.99.11) from Geobacter metallireducens
PFams: PFL-like, Gly_radical
862 amino acids: PaperBLAST, CDD, Compare to cluster

Q8L1A3 benzylsuccinate synthase (EC 4.1.99.11) from Thauera sp. DNT-1
PFams: PFL-like, Gly_radical
864 amino acids: PaperBLAST, CDD, Compare to cluster

Q8VPT7 benzylsuccinate synthase α subunit (EC 4.1.99.11) from Azoarcus sp. T
Q8VPT7 benzylsuccinate synthase (EC 4.1.99.11) from Azoarcus sp.
PFams: PFL-like, Gly_radical
Heteromeric, 864 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 6 336-342 amino acids (not heteromeric)

A4IQU1 spore photoproduct lyase (EC 4.1.99.14) from Geobacillus thermodenitrificans
341 amino acids: PaperBLAST, CDD, Compare to cluster

P37956 spore photoproduct lyase monomer (EC 4.1.99.14) from Bacillus subtilis (strain 168)
SPL_BACSU / P37956 Spore photoproduct lyase; EC 4.1.99.14 from Bacillus subtilis (strain 168)
P37956 spore photoproduct lyase (EC 4.1.99.14) from Bacillus subtilis
GI|289270 spore photoproduct lyase from Bacillus subtilis
342 amino acids: PaperBLAST, CDD, Compare to cluster

SPLB_CLOAB / Q97L63 Spore photoproduct lyase; EC 4.1.99.14 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Q97L63 spore photoproduct lyase (EC 4.1.99.14) from Clostridium acetobutylicum
PFams: Radical_SAM
336 amino acids: PaperBLAST, CDD, Compare to cluster

SPL_GEOSY / C9RZ55 Spore photoproduct lyase; EC 4.1.99.14 from Geobacillus sp. (strain Y412MC61)
341 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 7 725-771 amino acids (not heteromeric)

A9F845 geosmin synthase (EC 4.1.99.16) from Sorangium cellulosum
771 amino acids: PaperBLAST, CDD, Compare to cluster

B0FLN6 geosmin synthase (EC 4.1.99.16); germacradienol synthase (EC 4.2.3.22) from Streptomyces peucetius
732 amino acids: PaperBLAST, CDD, Compare to cluster

Q82L49 geosmin synthase (EC 4.1.99.16); germacradienol synthase (EC 4.2.3.22) from Streptomyces avermitilis
725 amino acids: PaperBLAST, CDD, Compare to cluster

Q9X839 geosmin synthase (EC 4.1.99.16; EC 4.2.3.22) from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
CYC2_STRCO / Q9X839 Germacradienol/geosmin synthase; EC 4.2.3.22; EC 4.2.3.75; EC 4.1.99.16 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Q9X839 geosmin synthase (EC 4.1.99.16); germacradienol synthase (EC 4.2.3.22) from Streptomyces coelicolor
726 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 8 425-543 amino acids (not heteromeric)

RIBA2_ARATH / Q6NLQ7 Monofunctional riboflavin biosynthesis protein RIBA 2, chloroplastic; EC 4.1.99.12 from Arabidopsis thaliana (Mouse-ear cress)
Q6NLQ7 3,4-dihydroxy-2-butanone-4-phosphate synthase (EC 4.1.99.12) from Arabidopsis thaliana
PFams: DHBP_synthase, GTP_cyclohydro2
476 amino acids: PaperBLAST, CDD, Compare to cluster

A5U2B7 3,4-dihydroxy-2-butanone-4-phosphate synthase (EC 4.1.99.12) from Mycobacterium tuberculosis
P9WHF1 GTP cyclohydrolase II (EC 3.5.4.25) from Mycobacterium tuberculosis
PFams: DHBP_synthase, GTP_cyclohydro2
425 amino acids: PaperBLAST, CDD, Compare to cluster

P47924 chloroplastic riboflavin biosynthesis protein ribBA (EC 3.5.4.25; EC 4.1.99.12) from Arabidopsis thaliana
RIBA1_ARATH / P47924 Bifunctional riboflavin biosynthesis protein RIBA 1, chloroplastic; AtRIBA1; EC 4.1.99.12; EC 3.5.4.25 from Arabidopsis thaliana (Mouse-ear cress)
P47924 3,4-dihydroxy-2-butanone-4-phosphate synthase (EC 4.1.99.12) from Arabidopsis thaliana
PFams: DHBP_synthase, GTP_cyclohydro2
543 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 9 74-76 amino acids (heteromeric)

O87944 benzylsuccinate synthase β subunit from Thauera aromatica
BSSB_THAAR / O87944 Benzylsuccinate synthase beta subunit; EC 4.1.99.11 from Thauera aromatica
O87944 benzylsuccinate synthase (subunit 2/3) (EC 4.1.99.11) from Thauera aromatica
PFams: BssB_TutG
Heteromeric, 74 amino acids: PaperBLAST, CDD, Compare to cluster

Q8VPT6 benzylsuccinate synthase β subunit (EC 4.1.99.11) from Azoarcus sp. T
PFams: BssB_TutG
Heteromeric, 76 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 10 57-60 amino acids (heteromeric)

O87942 benzylsuccinate synthase γ subunit from Thauera aromatica
BSSC_THAAR / O87942 Benzylsuccinate synthase gamma subunit; EC 4.1.99.11 from Thauera aromatica
O87942 benzylsuccinate synthase (subunit 1/3) (EC 4.1.99.11) from Thauera aromatica
PFams: BssC_TutF
Heteromeric, 57 amino acids: PaperBLAST, CDD, Compare to cluster

Q8VPT8 benzylsuccinate synthase γ subunit (EC 4.1.99.11) from Azoarcus sp. T
PFams: BssC_TutF
Heteromeric, 60 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 11 377-377 amino acids (heteromeric)

b3990 2-iminoacetate synthase (EC 4.1.99.19) from Escherichia coli K-12 substr. MG1655
P30140 2-iminoacetate synthase (EC 4.1.99.19) from Escherichia coli (strain K12)
THIH_ECOLI / P30140 2-iminoacetate synthase; Dehydroglycine synthase; Tyrosine lyase; EC 4.1.99.19 from Escherichia coli (strain K12)
P30140 2-iminoacetate synthase (EC 4.1.99.19) from Escherichia coli
CH_004017 thiazole biosynthesis protein ThiH from Escherichia coli K12
PFams: Radical_SAM, BATS
Heteromeric, 377 amino acids: PaperBLAST, CDD, Compare to cluster

THIH_SALTY / Q9S498 2-iminoacetate synthase; Dehydroglycine synthase; Tyrosine lyase; EC 4.1.99.19 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q9S498 2-iminoacetate synthase (EC 4.1.99.19) from Salmonella enterica subsp. enterica serovar Typhimurium
PFams: Radical_SAM, BATS
Heteromeric, 377 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 12 507-508 amino acids (not heteromeric)

Q3IXP1 (6-4)DNA photolyase (EC 4.1.99.13) from Rhodobacter sphaeroides
PFams: DPRP
508 amino acids: PaperBLAST, CDD, Compare to cluster

PHRB_AGRFC / A9CH39 (6-4) photolyase; (6-4)DNA photolyase; DNA photolyase PhrB; Photoreactivating enzyme PhrB; EC 4.1.99.13 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
A9CH39 (6-4)DNA photolyase (EC 4.1.99.13) from Agrobacterium tumefaciens
PFams: DPRP
507 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/4 heteromeric)

D4GV87 phosphomethylpyrimidine synthase (EC 4.1.99.17) from Haloferax volcanii
PFams: ThiC_Rad_SAM
482 amino acids: PaperBLAST, CDD

P43534 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
THI5_YEAST / P43534 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI5; HMP-P synthase; Hydroxymethylpyrimidine phosphate synthase; Thiamine biosynthesis protein 5; Thiamine pyrimidine synthase from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P43534 phosphomethylpyrimidine synthase (EC 4.1.99.17) from Saccharomyces cerevisiae
PFams: NMT1
340 amino acids: PaperBLAST, CDD

Q86RA1 (6-4)DNA photolyase (EC 4.1.99.13) from Aphrocallistes vastus
PFams: DNA_photolyase, FAD_binding_7
563 amino acids: PaperBLAST, CDD

Q97F53 spore photoproduct lyase monomer (EC 4.1.99.14) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
347 amino acids: PaperBLAST, CDD