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Clusters of Characterized Proteins

Searching for 4.2.1.12

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Found 32 characterized proteins with matching descriptions. 2 of these are heteromeric.

Fetched 32 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 29 of these sequences

Found 7 clusters of similar sequences. Another 3 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 389-506 amino acids (2/7 heteromeric)

P50909 β subunit of tryptophan synthase (EC 4.2.1.122) from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
P50909 tryptophan synthase (EC 4.2.1.20) from Thermotoga maritima
PFams: PALP
389 amino acids: PaperBLAST, CDD, Compare to cluster

b1261 tryptophan synthase subunit β (EC 4.2.1.122) from Escherichia coli K-12 substr. MG1655
P0A879 tryptophan synthase subunit β (EC 4.2.1.122) from Escherichia coli (strain K12)
P0A879 tryptophan synthase (EC 4.2.1.20) from Escherichia coli
PFams: PALP
397 amino acids: PaperBLAST, CDD, Compare to cluster

P14671 tryptophan synthase, beta subunit (EC 4.2.1.122) from Arabidopsis thaliana
P14671 tryptophan synthase (EC 4.2.1.20) from Arabidopsis thaliana
PFams: PALP
470 amino acids: PaperBLAST, CDD, Compare to cluster

Q5JDJ1 tryptophan synthase (indole-salvaging) (EC 4.2.1.122); tryptophan synthase (subunit 1/2) (EC 4.2.1.20) from Thermococcus kodakarensis
PFams: PALP
Heteromeric, 442 amino acids: PaperBLAST, CDD, Compare to cluster

Q9FFW8 tryptophan synthase, beta subunit (EC 4.2.1.122) from Arabidopsis thaliana
Q9FFW8 tryptophan synthase (EC 4.2.1.20) from Arabidopsis thaliana
PFams: PALP
506 amino acids: PaperBLAST, CDD, Compare to cluster

Q9WZ09 tryptophan synthase β2 subunit (EC 4.2.1.122) from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
PFams: PALP
422 amino acids: PaperBLAST, CDD, Compare to cluster

Q9YGB0 tryptophan synthase β subunit (EC 4.2.1.122) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Q9YGB0 tryptophan synthase (indole-salvaging) (EC 4.2.1.122); tryptophan synthase (subunit 2/2) (EC 4.2.1.20) from Thermococcus kodakarensis
PFams: PALP
Heteromeric, 389 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 490-512 amino acids (not heteromeric)

A4YGC7 4-hydroxybutyryl-CoA dehydratase (EC 4.2.1.120) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
A4YGC7 4-hydroxybutanoyl-CoA dehydratase (EC 4.2.1.120) from Metallosphaera sedula
PFams: HpaB_N, HpaB
507 amino acids: PaperBLAST, CDD, Compare to cluster

A8AA25 4-hydroxybutanoyl-CoA dehydratase (EC 4.2.1.120) from Ignicoccus hospitalis
PFams: HpaB_N, HpaB
512 amino acids: PaperBLAST, CDD, Compare to cluster

B1YBY6 4-hydroxybutanoyl-CoA dehydratase (EC 4.2.1.120) from Pyrobaculum neutrophilum
PFams: HpaB_N, HpaB
497 amino acids: PaperBLAST, CDD, Compare to cluster

P55792 4-hydroxybutyryl-CoA dehydratase subunit (EC 4.2.1.120) from Clostridium aminobutyricum
HDVD_CLOAM / P55792 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase; 4-BUDH; Gamma-aminobutyrate metabolism dehydratase/isomerase; EC 4.2.1.120; EC 5.3.3.3 from Clostridium aminobutyricum
P55792 4-hydroxybutanoyl-CoA dehydratase (EC 4.2.1.120) from Clostridium aminobutyricum
PFams: HpaB_N, HpaB
490 amino acids: PaperBLAST, CDD, Compare to cluster

A9A1Y2 4-hydroxybutanoyl-CoA dehydratase (EC 4.2.1.120) from Nitrosopumilus maritimus (strain SCM1)
PFams: HpaB_N, HpaB
508 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 472-478 amino acids (not heteromeric)

DES_TOBAC / Q8W2N5 9-divinyl ether synthase; NtDES1; Colneleate synthase; Cytochrome P450 74D3; EC 4.2.1.121 from Nicotiana tabacum (Common tobacco)
Q8W2N5 colneleate synthase (EC 4.2.1.121) from Nicotiana tabacum
PFams: p450
478 amino acids: PaperBLAST, CDD, Compare to cluster

Q9AVQ1 9-divinyl ether synthase (EC 4.2.1.121) from Solanum tuberosum
DES_SOLTU / Q9AVQ1 9-divinyl ether synthase; StDES; Colneleate synthase; Cytochrome P450 74D2; EC 4.2.1.121 from Solanum tuberosum (Potato)
Q9AVQ1 colneleate synthase (EC 4.2.1.121) from Solanum tuberosum
PFams: p450
478 amino acids: PaperBLAST, CDD, Compare to cluster

DES_SOLLC / Q9FPM6 9-divinyl ether synthase; LeDES; Colneleate synthase; Cytochrome P450 74D1; EC 4.2.1.121 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Q9FPM6 colneleate synthase (EC 4.2.1.121) from Solanum lycopersicum
PFams: p450
478 amino acids: PaperBLAST, CDD, Compare to cluster

Q2WE96 9/13-divinyl ether synthase (EC 4.2.1.121) from Allium sativum
PFams: p450
472 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 757-769 amino acids (not heteromeric)

M4WEZ8 dammarenediol II synthase (EC 4.2.1.125) from Panax quinquefolius
PFams: SQHop_cyclase_N, Prenyltrans, SQHop_cyclase_C, Prenyltrans, Prenyltrans
769 amino acids: PaperBLAST, CDD, Compare to cluster

LUP1_ARATH / Q9C5M3 Lupeol synthase 1; AtLUP1; Lupan-3-beta,20-diol synthase; EC 4.2.1.128; EC 5.4.99.41 from Arabidopsis thaliana (Mouse-ear cress)
Q9C5M3 lupan-3beta,20-diol synthase (EC 4.2.1.128); lupeol synthase (EC 5.4.99.41) from Arabidopsis thaliana
PFams: SQHop_cyclase_N, Prenyltrans, SQHop_cyclase_C, Prenyltrans, Prenyltrans
757 amino acids: PaperBLAST, CDD, Compare to cluster

Q08IT1 dammarenediol-II synthase (EC 4.2.1.125) from Panax ginseng
DADIS_PANGI / Q08IT1 Dammarenediol II synthase; Dammarenediol synthase; PgDDS; EC 4.2.1.125 from Panax ginseng (Korean ginseng)
Q08IT1 dammarenediol II synthase (EC 4.2.1.125) from Panax ginseng
PFams: SQHop_cyclase_N, Prenyltrans, SQHop_cyclase_C, Prenyltrans, Prenyltrans
769 amino acids: PaperBLAST, CDD, Compare to cluster

Q9FR95 arabidiol synthase (EC 4.2.1.124) from Arabidopsis thaliana
PEN1_ARATH / Q9FR95 Arabidiol synthase; Pentacyclic triterpene synthase 1; AtPEN1; EC 4.2.1.124 from Arabidopsis thaliana (Mouse-ear cress)
PFams: SQHop_cyclase_N, Prenyltrans, SQHop_cyclase_C, Prenyltrans, Prenyltrans
766 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 277-303 amino acids (not heteromeric)

G8UQI0 N-acetylmuramic acid 6-phosphate etherase (EC 4.2.1.126) from Tannerella forsythia
PFams: SIS_2, SIS
277 amino acids: PaperBLAST, CDD, Compare to cluster

P44862 N-acetylmuramic acid 6-phosphate etherase (EC 4.2.1.126) from Haemophilus influenzae
PFams: SIS_2, SIS
303 amino acids: PaperBLAST, CDD, Compare to cluster

b2428 N-acetylmuramic acid 6-phosphate etherase (EC 4.2.1.126) from Escherichia coli K-12 substr. MG1655
P76535 N-acetylmuramic acid 6-phosphate etherase (EC 4.2.1.126) from Escherichia coli (strain K12)
MURQ_ECOLI / P76535 N-acetylmuramic acid 6-phosphate etherase; MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase; EC 4.2.1.126 from Escherichia coli (strain K12)
PFams: SIS_2, SIS
298 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 6 603-608 amino acids (not heteromeric)

Q1PAG1 phosphogluconate dehydratase (EC 4.2.1.12) from Pseudomonas chlororaphis
PFams: ILVD_EDD
608 amino acids: PaperBLAST, CDD, Compare to cluster

b1851 phosphogluconate dehydratase (EC 4.2.1.12) from Escherichia coli K-12 substr. MG1655
P0ADF6 phosphogluconate dehydratase (EC 4.2.1.12) from Escherichia coli (strain K12)
EDD_ECOLI / P0ADF6 Phosphogluconate dehydratase; 6-phosphogluconate dehydratase; Entner-Doudoroff dehydrase; EC 4.2.1.12 from Escherichia coli (strain K12)
RF|NP_416365 phosphogluconate dehydratase from Escherichia coli K12
PFams: ILVD_EDD
603 amino acids: PaperBLAST, CDD, Compare to cluster

EDD_ZYMMO / P21909 Phosphogluconate dehydratase; 6-phosphogluconate dehydratase; EC 4.2.1.12 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
PFams: ILVD_EDD
607 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 7 631-695 amino acids (not heteromeric)

A8R7G4 hydroxyhopane synthase (EC 4.2.1.129; EC 5.4.99.17) from Adiantum capillus-veneris
PFams: SQHop_cyclase_N, Prenyltrans, SQHop_cyclase_C, Prenyltrans, Prenyltrans, Prenyltrans, SQHop_cyclase_C, Prenyltrans
695 amino acids: PaperBLAST, CDD, Compare to cluster

B3QHC3 squalene hopene cyclase (EC 4.2.1.129; EC 5.4.99.17) from Rhodopseudomonas palustris (strain TIE-1)
PFams: SQHop_cyclase_N, Prenyltrans, SQHop_cyclase_C, Prenyltrans, Prenyltrans, Prenyltrans
653 amino acids: PaperBLAST, CDD, Compare to cluster

P33247 squalene-hopene cyclase subunit (EC 4.2.1.129; EC 5.4.99.17) from Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / JCM 5260 / NBRC 15652 / NCIMB 11725 / NRRL B-14509 / 104-1A)
P33247 squalene-hopanol cyclase (EC 4.2.1.129); squalene-hopene cyclase (EC 5.4.99.17) from Alicyclobacillus acidocaldarius
PFams: Prenyltrans, SQHop_cyclase_N, Prenyltrans, Prenyltrans, SQHop_cyclase_C, Prenyltrans, Prenyltrans, Prenyltrans
631 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/3 heteromeric)

A0A2U8JPY3 tryptophan synthase (indole-salvaging) (EC 4.2.1.122); tryptophan synthase (EC 4.2.1.20) from Psilocybe cubensis
PFams: Trp_syntA, PALP
700 amino acids: PaperBLAST, CDD

Q24FB1 tetrahymanol synthase (EC 4.2.1.123) from Tetrahymena thermophila
PFams: SQHop_cyclase_N, SQHop_cyclase_C, Prenyltrans, TED_complement, Prenyltrans
655 amino acids: PaperBLAST, CDD

E1XUJ2 linalool dehydratase/isomerase monomer (EC 5.4.4.4; EC 4.2.1.127) from Castellaniella defragrans
LDI_CASDE / E1XUJ2 Linalool dehydratase/isomerase; Geraniol isomerase; Linalool dehydratase-isomerase; Myrcene hydratase; EC 4.2.1.127; EC 5.4.4.4 from Castellaniella defragrans (Alcaligenes defragrans)
E1XUJ2 linalool dehydratase (EC 4.2.1.127); geraniol isomerase (EC 5.4.4.4) from Castellaniella defragrans
PFams: Ldi, Ldi
397 amino acids: PaperBLAST, CDD