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Clusters of Characterized Proteins

Searching for 4.2.1.2 as complete word(s)

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Found 33 characterized proteins with matching descriptions. 4 of these are heteromeric.

Fetched 33 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 32 of these sequences

Found 5 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 438-512 amino acids (not heteromeric)

A0A251UH44 fumarate hydratase (EC 4.2.1.2) from Helianthus annuus
PFams: Lyase_1, FumaraseC_C
494 amino acids: PaperBLAST, CDD, Compare to cluster

A0A251UZF1 fumarate hydratase (EC 4.2.1.2) from Helianthus annuus
PFams: Lyase_1, FumaraseC_C
492 amino acids: PaperBLAST, CDD, Compare to cluster

A5Y6J1 fumarate hydratase (EC 4.2.1.2) from Streptomyces thermovulgaris
PFams: Lyase_1, FumaraseC_C
461 amino acids: PaperBLAST, CDD, Compare to cluster

b1611 fumarase C (EC 4.2.1.2) from Escherichia coli K-12 substr. MG1655
FUMC_ECOLI / P05042 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Escherichia coli (strain K12)
P05042 fumarate hydratase (EC 4.2.1.2) from Escherichia coli
P05042 fumarase C (EC 4.2.1.2) from Escherichia coli (strain K12)
PFams: Lyase_1, FumaraseC_C
467 amino acids: PaperBLAST, CDD, Compare to cluster

FUMH_HUMAN / P07954 Fumarate hydratase, mitochondrial; Fumarase; HsFH; EC 4.2.1.2 from Homo sapiens (Human)
P07954 fumarate hydratase (EC 4.2.1.2) from Homo sapiens
P07954 fumarate hydratase monomer (EC 4.2.1.2) from Homo sapiens
PFams: Lyase_1, FumaraseC_C
510 amino acids: PaperBLAST, CDD, Compare to cluster

FUMH_YEAST / P08417 Fumarate hydratase, mitochondrial; Fumarase; EC 4.2.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P08417 fumarate hydratase (EC 4.2.1.2) from Saccharomyces cerevisiae
PFams: Lyase_1, FumaraseC_C
488 amino acids: PaperBLAST, CDD, Compare to cluster

FUMH_RAT / P14408 Fumarate hydratase, mitochondrial; Fumarase; EC 4.2.1.2 from Rattus norvegicus (Rat)
P14408 fumarate hydratase (EC 4.2.1.2) from Rattus norvegicus
PFams: Lyase_1, FumaraseC_C
507 amino acids: PaperBLAST, CDD, Compare to cluster

P55250 fumarate hydratase (EC 4.2.1.2) from Rhizopus oryzae
PFams: Lyase_1, FumaraseC_C
494 amino acids: PaperBLAST, CDD, Compare to cluster

FUM1_ARATH / P93033 Fumarate hydratase 1, mitochondrial; AtFUM1; Fumarase 1; EC 4.2.1.2 from Arabidopsis thaliana (Mouse-ear cress)
P93033 fumarate hydratase (EC 4.2.1.2) from Arabidopsis thaliana
PFams: Lyase_1, FumaraseC_C
492 amino acids: PaperBLAST, CDD, Compare to cluster

FUMC_MYCTU / P9WN93 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WN93 fumarate hydratase (EC 4.2.1.2) from Mycobacterium tuberculosis
PFams: Lyase_1, FumaraseC_C
474 amino acids: PaperBLAST, CDD, Compare to cluster

Q13VI0 fumarate hydratase (EC 4.2.1.2) from Paraburkholderia xenovorans
PFams: Lyase_1, FumaraseC_C
466 amino acids: PaperBLAST, CDD, Compare to cluster

Q5SKT5 fumarate hydratase (EC 4.2.1.2) from Thermus thermophilus
PFams: Lyase_1, FumaraseC_C
466 amino acids: PaperBLAST, CDD, Compare to cluster

Q8NRN8 fumarate hydratase (EC 4.2.1.2) from Corynebacterium glutamicum
PFams: Lyase_1, FumaraseC_C
473 amino acids: PaperBLAST, CDD, Compare to cluster

FUM2_ARATH / Q9FI53 Fumarate hydratase 2; AtFUM2; Fumarase 2; EC 4.2.1.2 from Arabidopsis thaliana (Mouse-ear cress)
Q9FI53 fumarate hydratase (EC 4.2.1.2) from Arabidopsis thaliana
Q9FI53 fumarase (EC 4.2.1.2) from Arabidopsis thaliana
PFams: Lyase_1, FumaraseC_C
499 amino acids: PaperBLAST, CDD, Compare to cluster

FUMC_RICPR / Q9ZCQ4 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Rickettsia prowazekii (strain Madrid E)
Q9ZCQ4 fumarate hydratase (EC 4.2.1.2) from Rickettsia prowazekii
PFams: Lyase_1, FumaraseC_C
461 amino acids: PaperBLAST, CDD, Compare to cluster

FUMH_PIG / P10173 Fumarate hydratase, mitochondrial; Fumarase; EC 4.2.1.2 from Sus scrofa (Pig)
PFams: Lyase_1, FumaraseC_C
512 amino acids: PaperBLAST, CDD, Compare to cluster

FUMC_SACS2 / P39461 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
P39461 fumarate hydratase (EC 4.2.1.2) from Saccharolobus solfataricus
PFams: Lyase_1, FumaraseC_C
438 amino acids: PaperBLAST, CDD, Compare to cluster

FUMH_MOUSE / P97807 Fumarate hydratase, mitochondrial; Fumarase; EF-3; EC 4.2.1.2 from Mus musculus (Mouse)
PFams: Lyase_1, FumaraseC_C
507 amino acids: PaperBLAST, CDD, Compare to cluster

FUMC_RHIME / Q92PB6 Fumarate hydratase class II; Fumarase C; Aerobic fumarase; Iron-independent fumarase; EC 4.2.1.2 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
PFams: Lyase_1, FumaraseC_C
463 amino acids: PaperBLAST, CDD, Compare to cluster

O25883 fumarase (EC 4.2.1.2) from Helicobacter pylori (strain ATCC 700392 / 26695)
PFams: Lyase_1, FumaraseC_C
463 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 520-568 amino acids (not heteromeric)

b1612 fumarase A (EC 4.2.1.2; EC 5.3.2.2) from Escherichia coli K-12 substr. MG1655
FUMA_ECOLI / P0AC33 Fumarate hydratase class I, aerobic; Fumarase A; Oxaloacetate keto--enol-isomerase; OAAKE isomerase; Oxaloacetate tautomerase; EC 4.2.1.2; EC 5.3.2.2 from Escherichia coli (strain K12)
P0AC33 fumarate hydratase (EC 4.2.1.2); (S)-2-methylmalate dehydratase (EC 4.2.1.34) from Escherichia coli
P0AC33 fumarase A (EC 4.2.1.2; EC 5.3.2.2) from Escherichia coli (strain K12)
CH_021646 fumarate hydratase class I, aerobic; EC 4.2.1.2 from Escherichia coli K12
PFams: Fumerase, Fumerase_C
548 amino acids: PaperBLAST, CDD, Compare to cluster

b4122 fumarase B (EC 4.2.1.2; EC 4.2.1.81) from Escherichia coli K-12 substr. MG1655
FUMB_ECOLI / P14407 Fumarate hydratase class I, anaerobic; D-tartrate dehydratase; Fumarase B; EC 4.2.1.2; EC 4.2.1.81 from Escherichia coli (strain K12)
P14407 fumarate hydratase (EC 4.2.1.2); (S)-2-methylmalate dehydratase (EC 4.2.1.34) from Escherichia coli
P14407 fumarase B (EC 4.2.1.2; EC 4.2.1.81) from Escherichia coli (strain K12)
GB|AAC77083.1 fumarate hydratase class I, anaerobic; EC 4.2.1.2 from Escherichia coli K12
EW|b4122 anaerobic class I fumarate hydratase (fumarase B) from Escherichia coli K12
PFams: Fumerase, Fumerase_C
548 amino acids: PaperBLAST, CDD, Compare to cluster

Q141Z6 fumarate hydratase (EC 4.2.1.2); (S)-2-methylmalate dehydratase (EC 4.2.1.34) from Paraburkholderia xenovorans
PFams: Fumerase, Fumerase_C
520 amino acids: PaperBLAST, CDD, Compare to cluster

Q8X999 fumarate hydratase (EC 4.2.1.2) from Escherichia coli
PFams: Fumerase, Fumerase_C
550 amino acids: PaperBLAST, CDD, Compare to cluster

FUM2_LEIMA / E9AE57 Fumarate hydratase 2; Fumarase 2; LmFH-2; EC 4.2.1.2 from Leishmania major
PFams: Fumerase, Fumerase_C
568 amino acids: PaperBLAST, CDD, Compare to cluster

FUM1_LEIMA / Q4QAU9 Fumarate hydratase 1, mitochondrial; Fumarase 1; LmFH-1; EC 4.2.1.2 from Leishmania major
PFams: Fumerase, Fumerase_C
549 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 169-169 amino acids (not heteromeric)

b2929 fumarase E (EC 4.2.1.2) from Escherichia coli K-12 substr. MG1655
FUME_ECOLI / P11663 Fumarase E; EC 4.2.1.2 from Escherichia coli (strain K12)
P11663 fumarase E (EC 4.2.1.2) from Escherichia coli (strain K12)
PFams: MtlR
169 amino acids: PaperBLAST, CDD, Compare to cluster

FUME_SHIFL / Q83Q96 Fumarase E; EC 4.2.1.2 from Shigella flexneri
PFams: MtlR
169 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 272-288 amino acids (heteromeric)

B1Y932 fumarate hydratase (subunit 1/2) (EC 4.2.1.2) from Pyrobaculum neutrophilum
PFams: Fumerase
Heteromeric, 288 amino acids: PaperBLAST, CDD, Compare to cluster

Q8U062 fumarate hydratase (subunit 2/2) (EC 4.2.1.2) from Pyrococcus furiosus
PFams: Fumerase
Heteromeric, 272 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 166-201 amino acids (heteromeric)

B1Y931 fumarate hydratase (subunit 2/2) (EC 4.2.1.2) from Pyrobaculum neutrophilum
PFams: Fumerase_C
Heteromeric, 201 amino acids: PaperBLAST, CDD, Compare to cluster

Q8U063 fumarate hydratase (subunit 1/2) (EC 4.2.1.2) from Pyrococcus furiosus
PFams: Fumerase_C
Heteromeric, 166 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

b1675 fumarase D (EC 4.2.1.2) from Escherichia coli K-12 substr. MG1655
FUMD_ECOLI / P0ACX5 Fumarase D; EC 4.2.1.2 from Escherichia coli (strain K12)
P0ACX5 fumarase D (EC 4.2.1.2) from Escherichia coli (strain K12)
PFams: DUF2767
69 amino acids: PaperBLAST, CDD