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Clusters of Characterized Proteins

Searching for 4.3.2.1

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Found 25 characterized proteins with matching descriptions. 12 of these are heteromeric.

Fetched 25 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 25 of these sequences

Found 4 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 457-470 amino acids (not heteromeric)

P04424 argininosuccinate lyase (EC 4.3.2.1) from Homo sapiens
ARLY_HUMAN / P04424 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Homo sapiens (Human)
P04424 argininosuccinate lyase (EC 4.3.2.1) from Homo sapiens
PFams: Lyase_1, ASL_C2
464 amino acids: PaperBLAST, CDD, Compare to cluster

P9WPY7 argininosuccinate lyase (EC 4.3.2.1) from Mycobacterium tuberculosis
PFams: Lyase_1, ASL_C2
470 amino acids: PaperBLAST, CDD, Compare to cluster

Q8DVX5 argininosuccinate lyase (EC 4.3.2.1) from Streptococcus mutans
PFams: Lyase_1, ASL_C2
460 amino acids: PaperBLAST, CDD, Compare to cluster

Q9P870 argininosuccinate lyase (EC 4.3.2.1) from Agaricus bisporus
PFams: Lyase_1, ASL_C2
463 amino acids: PaperBLAST, CDD, Compare to cluster

RF|NP_595129.1 argininosuccinate lyase; EC 4.3.2.1 from Schizosaccharomyces pombe
PFams: Lyase_1, ASL_C2
461 amino acids: PaperBLAST, CDD, Compare to cluster

ARLY_YEAST / P04076 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Lyase_1, ASL_C2
463 amino acids: PaperBLAST, CDD, Compare to cluster

ARLY2_ANAPL / P24058 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin II; Delta-2 crystallin; EC 4.3.2.1 from Anas platyrhynchos (Mallard) (Anas boschas)
PFams: Lyase_1, ASL_C2
468 amino acids: PaperBLAST, CDD, Compare to cluster

ARLY_ANSAN / P33110 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin; EC 4.3.2.1 from Anser anser anser (Western greylag goose)
PFams: Lyase_1, ASL_C2
466 amino acids: PaperBLAST, CDD, Compare to cluster

ARLY_COLLI / Q01592 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin; EC 4.3.2.1 from Columba livia (Rock dove)
PFams: Lyase_1, ASL_C2
466 amino acids: PaperBLAST, CDD, Compare to cluster

ARLY_NOSP7 / Q9LAE5 Argininosuccinate lyase; ASAL; ASL; Arginosuccinase; EC 4.3.2.1 from Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Q9LAE5 argininosuccinate lyase (EC 4.3.2.1) from Nostoc sp.
PFams: Lyase_1, ASL_C2
461 amino acids: PaperBLAST, CDD, Compare to cluster

b3960 argininosuccinate lyase (EC 4.3.2.1) from Escherichia coli K-12 substr. MG1655
P11447 argininosuccinate lyase (EC 4.3.2.1) from Escherichia coli (strain K12)
PFams: Lyase_1, ASL_C2
457 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 190-213 amino acids (heteromeric)

Q5NMD4 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Zymomonas mobilis
PFams: GATase, GATase_3
Heteromeric, 213 amino acids: PaperBLAST, CDD, Compare to cluster

Q8ZY40 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Pyrobaculum aerophilum
PFams: SNO, GATase
Heteromeric, 190 amino acids: PaperBLAST, CDD, Compare to cluster

Q9X0C8 imidazole-glycerol-phosphate synthase glutamine amidotransferase subunit (EC 4.3.2.10) from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
HIS5_THEMA / Q9X0C8 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; TmHisH; EC 4.3.2.10; EC 3.5.1.2 from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Q9X0C8 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Thermotoga maritima
PFams: GATase_3, GATase, SNO
Heteromeric, 201 amino acids: PaperBLAST, CDD, Compare to cluster

b2023 imidazole glycerol phosphate synthase subunit HisH (EC 4.3.2.10) from Escherichia coli K-12 substr. MG1655
P60595 imidazole glycerol phosphate synthase subunit HisH (EC 4.3.2.10) from Escherichia coli (strain K12)
HIS5_ECOLI / P60595 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Escherichia coli (strain K12)
RF|NP_416527 IGP synthase glutamine amidotransferase subunit; EC 2.4.2.- from Escherichia coli K12
PFams: GATase, GATase_3
Heteromeric, 196 amino acids: PaperBLAST, CDD, Compare to cluster

HIS5_MYCBO / P59957 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
PFams: GATase, GATase_3
Heteromeric, 206 amino acids: PaperBLAST, CDD, Compare to cluster

HIS5_THET8 / Q7SIC0 Imidazole glycerol phosphate synthase subunit HisH; IGP synthase glutaminase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; EC 4.3.2.10; EC 3.5.1.2 from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Q7SIC0 imidazole glycerol-phosphate synthase (subunit 2/2) (EC 4.3.2.10) from Thermus thermophilus
PFams: GATase, SNO, GATase_3
Heteromeric, 200 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 251-258 amino acids (heteromeric)

A4WHB6 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Pyrobaculum arsenaticum
PFams: His_biosynth, Dus, DHO_dh
Heteromeric, 251 amino acids: PaperBLAST, CDD, Compare to cluster

Q5NMD6 imidazole glycerol-phosphate synthase (subunit 2/2) (EC 4.3.2.10) from Zymomonas mobilis
PFams: His_biosynth
Heteromeric, 255 amino acids: PaperBLAST, CDD, Compare to cluster

Q8ZY16 imidazole glycerol-phosphate synthase (subunit 2/2) (EC 4.3.2.10) from Pyrobaculum aerophilum
PFams: His_biosynth, Dus
Heteromeric, 253 amino acids: PaperBLAST, CDD, Compare to cluster

Q9X0C6 imidazole-glycerol-phosphate synthase cycloligase subunit (EC 4.3.2.10) from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
HIS6_THEMA / Q9X0C6 Imidazole glycerol phosphate synthase subunit HisF; IGP synthase cyclase subunit; IGP synthase subunit HisF; ImGP synthase subunit HisF; IGPS subunit HisF; EC 4.3.2.10 from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Q9X0C6 imidazole glycerol-phosphate synthase (subunit 2/2) (EC 4.3.2.10) from Thermotoga maritima
PFams: His_biosynth
Heteromeric, 253 amino acids: PaperBLAST, CDD, Compare to cluster

b2025 imidazole glycerol phosphate synthase subunit HisF (EC 4.3.2.10) from Escherichia coli K-12 substr. MG1655
P60664 imidazole glycerol phosphate synthase subunit HisF (EC 4.3.2.10) from Escherichia coli (strain K12)
HIS6_ECOLI / P60664 Imidazole glycerol phosphate synthase subunit HisF; IGP synthase cyclase subunit; IGP synthase subunit HisF; ImGP synthase subunit HisF; IGPS subunit HisF; EC 4.3.2.10 from Escherichia coli (strain K12)
RF|NP_416529 IGP synthase cyclase subunit; EC 4.1.3.- from Escherichia coli K12
PFams: His_biosynth
Heteromeric, 258 amino acids: PaperBLAST, CDD, Compare to cluster

HIS6_THET8 / Q7SIB9 Imidazole glycerol phosphate synthase subunit HisF; IGP synthase cyclase subunit; IGP synthase subunit HisF; ImGP synthase subunit HisF; IGPS subunit HisF; EC 4.3.2.10 from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Q7SIB9 imidazole glycerol-phosphate synthase (subunit 1/2) (EC 4.3.2.10) from Thermus thermophilus
PFams: His_biosynth
Heteromeric, 252 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 552-592 amino acids (not heteromeric)

HIS5_YEAST / P33734 Imidazole glycerol phosphate synthase hisHF; IGP synthase; IGPS; ImGP synthase; EC 4.3.2.10; EC 3.5.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P33734 imidazole glycerol-phosphate synthase (EC 4.3.2.10) from Saccharomyces cerevisiae
PFams: GATase, GATase_3, His_biosynth
552 amino acids: PaperBLAST, CDD, Compare to cluster

Q9SZ30 imidazole-glycerol-phosphate synthase (EC 4.3.2.10) from Arabidopsis thaliana
Q9SZ30 imidazole glycerol-phosphate synthase (EC 4.3.2.10) from Arabidopsis thaliana
PFams: GATase, SNO, GATase_3, His_biosynth
592 amino acids: PaperBLAST, CDD, Compare to cluster