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Clusters of Characterized Proteins

Searching for 5.4.99.2 as complete word(s)

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Found 20 characterized proteins with matching descriptions. 8 of these are heteromeric.

Fetched 20 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 20 of these sequences

Found 4 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 553-750 amino acids (5/14 heteromeric)

MCM_RHIME / O86028 Methylmalonyl-CoA mutase; MCM; EC 5.4.99.2 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
PFams: MM_CoA_mutase, B12-binding
712 amino acids: PaperBLAST, CDD, Compare to cluster

A4YEG1 methylmalonyl-CoA mutase (subunit 2/2) (EC 5.4.99.2) from Metallosphaera sedula
PFams: MM_CoA_mutase
Heteromeric, 553 amino acids: PaperBLAST, CDD, Compare to cluster

O74009 methylmalonyl-CoA mutase (subunit 2/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: MM_CoA_mutase
Heteromeric, 563 amino acids: PaperBLAST, CDD, Compare to cluster

MUTB_PROFR / P11653 Methylmalonyl-CoA mutase large subunit; MCM-alpha; EC 5.4.99.2 from Propionibacterium freudenreichii subsp. shermanii
P11653 methylmalonyl-CoA mutase (EC 5.4.99.2) from Propionibacterium freudenreichii subsp. shermanii
P11653 methylmalonyl-CoA mutase large subunit (EC 5.4.99.2) from Propionibacterium freudenreichii subsp. shermanii
PFams: MM_CoA_mutase, B12-binding
Heteromeric, 728 amino acids: PaperBLAST, CDD, Compare to cluster

MUTA_HUMAN / P22033 Methylmalonyl-CoA mutase, mitochondrial; MCM; Methylmalonyl-CoA isomerase; EC 5.4.99.2 from Homo sapiens (Human)
P22033 methylmalonyl-CoA mutase (EC 5.4.99.2) from Homo sapiens
P22033 Methylmalonyl-CoA mutase, mitochondrial (EC 5.4.99.2) from Homo sapiens
PFams: MM_CoA_mutase, B12-binding
750 amino acids: PaperBLAST, CDD, Compare to cluster

Q23381 methylmalonyl-CoA mutase (EC 5.4.99.2) from Caenorhabditis elegans
PFams: MM_CoA_mutase, B12-binding
744 amino acids: PaperBLAST, CDD, Compare to cluster

Q84FZ1 methylmalonyl-CoA mutase (EC 5.4.99.2) from Methylorubrum extorquens
PFams: MM_CoA_mutase, B12-binding
721 amino acids: PaperBLAST, CDD, Compare to cluster

Q8MI68 methylmalonyl-CoA mutase (EC 5.4.99.2) from Sus scrofa
PFams: MM_CoA_mutase, B12-binding
750 amino acids: PaperBLAST, CDD, Compare to cluster

b2917 methylmalonyl-CoA mutase (EC 5.4.99.2) from Escherichia coli K-12 substr. MG1655
SCPA_ECOLI / P27253 Methylmalonyl-CoA mutase; MCM; EC 5.4.99.2 from Escherichia coli (strain K12)
P27253 methylmalonyl-CoA mutase (EC 5.4.99.2) from Escherichia coli (strain K12)
PFams: MM_CoA_mutase, B12-binding
714 amino acids: PaperBLAST, CDD, Compare to cluster

MCM_RHOS4 / Q3J4D7 Methylmalonyl-CoA mutase; MCM; EC 5.4.99.2 from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Q3J4D7 methylmalonyl-CoA mutase (EC 5.4.99.2) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
PFams: MM_CoA_mutase, B12-binding
709 amino acids: PaperBLAST, CDD, Compare to cluster

A9WI23 methylmalonyl-CoA mutase large subunit (EC 5.4.99.2) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
PFams: MM_CoA_mutase, B12-binding
Heteromeric, 733 amino acids: PaperBLAST, CDD, Compare to cluster

A9WI24 methylmalonyl-CoA mutase small subunit (EC 5.4.99.2) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
PFams: MM_CoA_mutase
Heteromeric, 717 amino acids: PaperBLAST, CDD, Compare to cluster

F1KUP0 methylmalonyl-CoA mutase subunit (EC 5.4.99.2) from Ascaris suum
PFams: MM_CoA_mutase, B12-binding
748 amino acids: PaperBLAST, CDD, Compare to cluster

Dsui_0519 Methylmalonyl-CoA mutase (EC 5.4.99.2) from Dechlorosoma suillum PS
PFams: MM_CoA_mutase, B12-binding
721 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 147-155 amino acids (heteromeric)

A4YIE3 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Metallosphaera sedula
PFams: B12-binding
Heteromeric, 155 amino acids: PaperBLAST, CDD, Compare to cluster

O58013 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: B12-binding
Heteromeric, 147 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 1099-1125 amino acids (not heteromeric)

Q8F222 methylmalonyl-CoA mutase (EC 5.4.99.2) from Leptospira interrogans serovar lai str. 56601
PFams: B12-binding, MeaB, cobW, MM_CoA_mutase
1125 amino acids: PaperBLAST, CDD, Compare to cluster

Q8Y2U5 methylmalonyl-CoA mutase (EC 5.4.99.2) from Ralstonia solanacearum
PFams: B12-binding, MeaB, cobW, MM_CoA_mutase
1099 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 605-638 amino acids (1/2 heteromeric)

P11652 methylmalonyl-CoA mutase (EC 5.4.99.2) from Propionibacterium freudenreichii subsp. shermanii
P11652 methylmalonyl-CoA mutase small subunit (EC 5.4.99.2) from Propionibacterium freudenreichii subsp. shermanii
PFams: MM_CoA_mutase
Heteromeric, 638 amino acids: PaperBLAST, CDD, Compare to cluster

Q6TMA2 methylmalonyl-CoA mutase (EC 5.4.99.2) from Methylorubrum extorquens
PFams: MM_CoA_mutase
605 amino acids: PaperBLAST, CDD, Compare to cluster