Other Characterized Proteins Similar to argD

GapMind for Amino acid biosynthesis

Other Characterized Proteins Similar to argD

Finding the characterized proteins for argD (N-acetylornithine aminotransferase) in L-arginine biosynthesis

Or see clustering for step argD

Or see all steps for L-arginine biosynthesis

Or cluster curated proteins matching a keyword

Definition of argD

Curated proteins or TIGRFams with EC 2.6.1.11
Ignore hits to items matching EC 2.6.1.81 when looking for 'other' hits
Ignore hits to items matching EC 2.6.1.19 when looking for 'other' hits
Ignore hits to MONOMER-18314 when looking for 'other' hits ([amino group carrier protein]-C-terminal-L-glutamyl-γ-L-lysine aminotransferase (EC 2.6.1.118; EC 2.6.1.124))
Ignore hits to items matching EC 2.6.1.48 when looking for 'other' hits
UniProt sequence A0A806JQF3: RecName: Full=Acetylornithine aminotransferase {ECO:0000256|HAMAP-Rule:MF_01107}; Short=ACOAT {ECO:0000256|HAMAP-Rule:MF_01107}; EC=2.6.1.11 {ECO:0000256|HAMAP-Rule:MF_01107};
Comment: This aminotransferase for converting N-acetylglutamate semialdehyde to acetylornithine is often similar to succinylornithine transaminases (EC 2.6.1.81), 4-aminobutyrate aminotransferases (EC 2.6.1.19), or 5-aminovalerate transaminases (EC 2.6.1.48). (Succinylornithine and 4-aminobutyrate transaminases are also reported to be active on N-acetylornithine and this seems likely for 5-aminovalerate transaminases as well.) link is given this EC nmber but is actually LysW-lysine/ornithine aminotransferase (LysJ). PMID:A0A806JQF3 show that Rv1655 (A0A806JQF3) from Mycobacterium tuberculosis is argD.

Fetched 14 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 18 other characterized sequences. (Found 31 hits including self hits.)

Removing ignored items reduces this to 2 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for argD.)

PP_4108 2-aminoadipate transaminase (EC 2.6.1.39) from Pseudomonas putida KT2440
Q88FI7 4-aminobutyrate aminotransferase (EC 2.6.1.39) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
2AAAT_PSEPK / Q88FI7 2-aminoadipate transaminase; 2-aminoadipate aminotransferase; L-2AA aminotransferase; EC 2.6.1.39 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
PFams: Aminotran_3
416 amino acids: PaperBLAST, CDD, SwissProt::Q88FI7
44% identical to

b2662 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli K-12 substr. MG1655
P22256 4-aminobutyrate aminotransferase GabT (EC 2.6.1.19; EC 2.6.1.48; EC 2.6.1.11) from Escherichia coli (strain K12)
GABT_ECOLI / P22256 4-aminobutyrate aminotransferase GabT; 5-aminovalerate transaminase; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBAT; EC 2.6.1.19; EC 2.6.1.48 from Escherichia coli (strain K12)
PFams: Aminotran_3
426 amino acids: PaperBLAST, CDD

Q93R93 L-2-aminoadipate semialdehyde transaminase monomer (EC 2.6.1.118) from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
LYSJ_THET2 / Q93R93 [LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.118 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
Q93R93 [amino group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase (EC 2.6.1.118) from Thermus thermophilus
PFams: Aminotran_3
395 amino acids: PaperBLAST, CDD, BRENDA::Q93R93
43% identical to

A0A806JQF3 Acetylornithine aminotransferase {ECO:0000256|HAMAP-Rule:MF_01107}; Short=ACOAT {ECO:0000256|HAMAP-Rule:MF_01107}; EC=2.6.1.11 {ECO:0000256|HAMAP-Rule:MF_01107}
400 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for argD.)

A0A140N9B6 succinylornithine transaminase (EC 2.6.1.81) from Escherichia coli
PFams: Aminotran_3, Aminotran_1_2
406 amino acids: PaperBLAST, CDD, BRENDA::A0A140N9B6
99% identical to

b1748 succinylornithine transaminase (EC 2.6.1.81; EC 2.6.1.11) from Escherichia coli K-12 substr. MG1655
P77581 succinylornithine transaminase (EC 2.6.1.81; EC 2.6.1.11) from Escherichia coli (strain K12)
ASTC_ECOLI / P77581 Succinylornithine transaminase; SOAT; Carbon starvation protein C; Succinylornithine aminotransferase; EC 2.6.1.81 from Escherichia coli (strain K12)
RF|NP_416262.1 succinylornithine transaminase; EC 2.6.1.81 from Escherichia coli K12
PFams: Aminotran_3, Aminotran_1_2
406 amino acids: PaperBLAST, CDD

ASTC_SALTY / Q8ZPV2 Succinylornithine transaminase; SOAT; Succinylornithine aminotransferase; EC 2.6.1.81 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aminotran_3, Aminotran_1_2
408 amino acids: PaperBLAST, CDD, SwissProt::Q8ZPV2
84% identical to

BWI76_RS11670 Succinylornithine transaminase (EC 2.6.1.81) from Klebsiella michiganensis M5al
PFams: Aminotran_3
406 amino acids: PaperBLAST, CDD, reanno::Koxy:BWI76_RS11670
82% identical to

PS417_21710 Succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas simiae WCS417
PFams: Aminotran_3
406 amino acids: PaperBLAST, CDD, reanno::WCS417:GFF4238
79% identical to

O30508 succinylornithine transaminase subunit (EC 2.6.1.13; EC 2.6.1.11; EC 2.6.1.81) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
ARUC_PSEAE / O30508 Succinylornithine transaminase/acetylornithine aminotransferase; ACOAT; SOAT; Succinylornithine aminotransferase; EC 2.6.1.11; EC 2.6.1.81 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
O30508 succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas aeruginosa
PFams: Aminotran_3, Aminotran_1_2
406 amino acids: PaperBLAST, CDD

Pf1N1B4_3440 Succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas fluorescens FW300-N1B4
PFams: Aminotran_3
406 amino acids: PaperBLAST, CDD, reanno::pseudo1_N1B4:Pf1N1B4_3440
79% identical to

Q4KKA1 4-aminobutyrate transaminase subunit (EC 2.6.1.19) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
PFams: Aminotran_3, Aminotran_1_2
425 amino acids: PaperBLAST, CDD, metacyc::MONOMER-11537
74% identical to

Pf6N2E2_4013 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas fluorescens FW300-N2E2
PFams: Aminotran_3, Aminotran_1_2
425 amino acids: PaperBLAST, CDD, reanno::pseudo6_N2E2:Pf6N2E2_4013
73% identical to

AO353_11510 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas fluorescens FW300-N2E3
PFams: Aminotran_3, Aminotran_1_2
425 amino acids: PaperBLAST, CDD, reanno::pseudo3_N2E3:AO353_11510
73% identical to

Q9I6M4 5-aminovalerate aminotransferase (EC 2.6.1.48) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
DAVT_PSEAE / Q9I6M4 5-aminovalerate aminotransferase DavT; 5-aminovalerate transaminase; Delta-aminovalerate aminotransferase; EC 2.6.1.48 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9I6M4 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas aeruginosa
PFams: Aminotran_3, Aminotran_1_2
426 amino acids: PaperBLAST, CDD, BRENDA::Q9I6M4
73% identical to

DAVT_PSEPK / Q88RB9 5-aminovalerate aminotransferase DavT; 5-aminovalerate transaminase; Delta-aminovalerate aminotransferase; EC 2.6.1.48 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Q88RB9 5-aminovalerate transaminase (EC 2.6.1.48) from Pseudomonas putida
PFams: Aminotran_3, Aminotran_1_2
425 amino acids: PaperBLAST, CDD, BRENDA::Q88RB9
73% identical to

Sama_2636 gamma-aminobutyrate transaminase (EC 2.6.1.19) from Shewanella amazonensis SB2B
PFams: Aminotran_3
425 amino acids: PaperBLAST, CDD, reanno::SB2B:6938533
68% identical to

b1302 4-aminobutyrate aminotransferase PuuE (EC 2.6.1.19; EC 2.6.1.48) from Escherichia coli K-12 substr. MG1655
P50457 4-aminobutyrate aminotransferase PuuE (EC 2.6.1.19; EC 2.6.1.48) from Escherichia coli (strain K12)
PUUE_ECOLI / P50457 4-aminobutyrate aminotransferase PuuE; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; EC 2.6.1.19 from Escherichia coli (strain K12)
PFams: Aminotran_3
421 amino acids: PaperBLAST, CDD, SwissProt::P50457
54% identical to

A0A5B8KQ12 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19) from Agrobacterium tumefaciens
PFams: Aminotran_3
426 amino acids: PaperBLAST, CDD, BRENDA::A0A5B8KQ12
54% identical to

Q0K2K2 4-aminobutyrate aminotransferase monomer (EC 2.6.1.19) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)
Q0K2K2 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19) from Cupriavidus necator
PFams: Aminotran_3
423 amino acids: PaperBLAST, CDD, BRENDA::Q0K2K2
53% identical to

A0A0U4XQS6 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19); 5-aminovalerate transaminase (EC 2.6.1.48) from Corynebacterium glutamicum
PFams: Aminotran_3
448 amino acids: PaperBLAST, CDD, BRENDA::A0A0U4XQS6
43% identical to

Q8NT35 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19) from Corynebacterium glutamicum
PFams: Aminotran_3
448 amino acids: PaperBLAST, CDD, BRENDA::Q8NT35
43% identical to