Other Characterized Proteins Similar to argD'B

GapMind for Amino acid biosynthesis

Other Characterized Proteins Similar to argD'B

Finding the characterized proteins for argD'B (N-succinylornithine aminotransferase) in L-arginine biosynthesis

Or see clustering for step argD'B

Or see all steps for L-arginine biosynthesis

Or cluster curated proteins matching a keyword

Definition of argD'B

Curated proteins or TIGRFams with EC 2.6.1.81
UniProt sequence Q8A1A8: SubName: Full=Acetylornithine aminotransferase {ECO:0000313|EMBL:AAO78863.1};
UniProt sequence L0G5F2_ECHVK: SubName: Full=Ornithine/acetylornithine aminotransferase {ECO:0000313|EMBL:AGA80060.1};
Ignore hits to items matching EC 2.6.1.11 when looking for 'other' hits
Comment: N-succinylglutamate semialdehyde => N-succinylornithine. Some Bacteroides hvae a diverged argD-like gene, i.e. BT3758 (Q8A1A8) or Echvi_3848 (L0G5F2_ECHVK), which are auxotrophic and cofit with other arg genes. Note that this is the same reaction as found in arginine degradation by the arginine succinyltransferase (AST) pathway

Fetched 12 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 10 other characterized sequences. (Found 20 hits including self hits.)

Removing ignored items reduces this to 2 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for argD'B.)

AZOBR_RS19025 acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] from Azospirillum brasilense Sp245
PFams: Aminotran_3
389 amino acids: PaperBLAST, CDD, reanno::azobra:AZOBR_RS19025
44% identical to

PS417_21710 Succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas simiae WCS417
PFams: Aminotran_3
406 amino acids: PaperBLAST, CDD

Q93R93 L-2-aminoadipate semialdehyde transaminase monomer (EC 2.6.1.118) from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
LYSJ_THET2 / Q93R93 [LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.118 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
Q93R93 [amino group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase (EC 2.6.1.118) from Thermus thermophilus
PFams: Aminotran_3
395 amino acids: PaperBLAST, CDD, BRENDA::Q93R93
42% identical to

O30508 succinylornithine transaminase subunit (EC 2.6.1.13; EC 2.6.1.11; EC 2.6.1.81) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
ARUC_PSEAE / O30508 Succinylornithine transaminase/acetylornithine aminotransferase; ACOAT; SOAT; Succinylornithine aminotransferase; EC 2.6.1.11; EC 2.6.1.81 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
O30508 succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas aeruginosa
PFams: Aminotran_3, Aminotran_1_2
406 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for argD'B.)

b3359 N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase (EC 2.6.1.11; EC 2.6.1.17) from Escherichia coli K-12 substr. MG1655
P18335 N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase (EC 2.6.1.11; EC 2.6.1.17) from Escherichia coli (strain K12)
ARGD_ECOLI / P18335 Acetylornithine/succinyldiaminopimelate aminotransferase; ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 from Escherichia coli (strain K12)
PFams: Aminotran_3, Aminotran_1_2
406 amino acids: PaperBLAST, CDD, SwissProt::P18335
66% identical to

ARGD_SALTY / P40732 Acetylornithine/succinyldiaminopimelate aminotransferase; ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aminotran_3, Aminotran_1_2
405 amino acids: PaperBLAST, CDD, SwissProt::P40732
65% identical to

P73133 bifunctional acetylornithine transaminase/4-aminobutyrate—2-oxoglutarate transaminase (EC 2.6.1.19; EC 2.6.1.11) from Synechocystis sp. (strain PCC 6803 / Kazusa)
P73133 acetylornithine transaminase (EC 2.6.1.11); 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19) from Synechococcus sp. PCC 6803
PFams: Aminotran_3
429 amino acids: PaperBLAST, CDD, BRENDA::P73133
45% identical to

Pf1N1B4_3440 Succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas fluorescens FW300-N1B4
PFams: Aminotran_3
406 amino acids: PaperBLAST, CDD

A8J933 acetylornithine transaminase (EC 2.6.1.11) from Chlamydomonas reinhardtii
PFams: Aminotran_3
460 amino acids: PaperBLAST, CDD, BRENDA::A8J933
44% identical to

ASTC_SALTY / Q8ZPV2 Succinylornithine transaminase; SOAT; Succinylornithine aminotransferase; EC 2.6.1.81 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aminotran_3, Aminotran_1_2
408 amino acids: PaperBLAST, CDD

ARGD_ARATH / Q9M8M7 Acetylornithine aminotransferase, chloroplastic/mitochondrial; ACOAT; Acetylornithine transaminase; AOTA; Protein HOPW1-1-INTERACTING 1; EC 2.6.1.11 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Aminotran_3
457 amino acids: PaperBLAST, CDD, SwissProt::Q9M8M7
43% identical to

PS417_21710 Succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas simiae WCS417
PFams: Aminotran_3
406 amino acids: PaperBLAST, CDD

B1XNF8 acetylornithine transaminase (EC 2.6.1.11); 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19) from Synechococcus sp. PCC 7002
PFams: Aminotran_3
418 amino acids: PaperBLAST, CDD, BRENDA::B1XNF8
40% identical to

PS417_21710 Succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas simiae WCS417
PFams: Aminotran_3
406 amino acids: PaperBLAST, CDD

RF|NP_588255.1 acetylornithine aminotransferase; EC 2.6.1.11 from Schizosaccharomyces pombe
PFams: Aminotran_3
441 amino acids: PaperBLAST, CDD, CharProtDB::CH_124889
42% identical to

P18544 acetylornithine transaminase (EC 2.6.1.11) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
ARGD_YEAST / P18544 Acetylornithine aminotransferase, mitochondrial; ACOAT; EC 2.6.1.11 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Aminotran_3
423 amino acids: PaperBLAST, CDD, SwissProt::P18544
40% identical to

PS417_21710 Succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas simiae WCS417
PFams: Aminotran_3
406 amino acids: PaperBLAST, CDD