Clusters of Characterized Proteins

Clustering the characterized proteins for argE'B (N-succinylcitrulline desuccinylase) in L-arginine biosynthesis

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Definition of argE'B

• Curated proteins matching N-succinylcitrulline desuccinylase
• Comment: The N-succinylcitrulline desuccinylase is probably BT3549 (Q8A1V9), Echvi_3851 (L0G443_ECHVK), or CA265_RS18500 (A0A1X9Z8E1_9SPHI) Mutants in these genes are rescued by added arginine and they are distantly related to succinyl-diaminopimelate desuccinylase. And these bacteria have ordinary argG/argH, so citrulline is expected to be an intermediate.

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 3 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 355-362 amino acids (not heteromeric)

BT3549 N-succinylcitrulline desuccinylase (EC 3.5.1.-) from Bacteroides thetaiotaomicron VPI-5482
PFams: Peptidase_M20, M20_dimer
355 amino acids: PaperBLAST, CDD, Compare to cluster

Echvi_3851 N-succinylcitrulline desuccinylase (EC 3.5.1.-) from Echinicola vietnamensis KMM 6221, DSM 17526
PFams: Peptidase_M20, M20_dimer
362 amino acids: PaperBLAST, CDD, Compare to cluster

CA265_RS18500 N-succinylcitrulline desuccinylase (EC 3.5.1.-) from Pedobacter sp. GW460-11-11-14-LB5
PFams: Peptidase_M20, M20_dimer
355 amino acids: PaperBLAST, CDD, Compare to cluster