Other Characterized Proteins Similar to carA

GapMind for Amino acid biosynthesis

Other Characterized Proteins Similar to carA

Finding the characterized proteins for carA (carbamoyl phosphate synthase subunit alpha) in L-arginine biosynthesis

Or see clustering for step carA

Or see all steps for L-arginine biosynthesis

Or cluster curated proteins matching a keyword

Definition of carA

Curated proteins matching carbamoyl-phosphate synthase%small
Ignore hits to items matching EC 6.3.5.5 when looking for 'other' hits
Ignore hits to items matching EC 6.3.4.16 when looking for 'other' hits
HMM TIGR01368
Comment: This could obtain the amino group from glutamine (EC 6.3.5.5) or from ammonia (EC 6.3.4.16)

Fetched 5 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 15 other characterized sequences. (Found 20 hits including self hits.)

Removing ignored items reduces this to 0 close sequences.

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for carA.)

B9V284 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Medicago truncatula
PFams: CPSase_sm_chain, GATase, Peptidase_C26
432 amino acids: PaperBLAST, CDD, BRENDA::B9V284
73% identical to

CARA_ARATH / Q9LVW7 Carbamoyl-phosphate synthase small chain, chloroplastic; Carbamoyl-phosphate synthetase glutamine chain; Protein VENOSA 6; EC 6.3.5.5 from Arabidopsis thaliana (Mouse-ear cress)
PFams: CPSase_sm_chain, GATase, Peptidase_C26
430 amino acids: PaperBLAST, CDD

Q8RSS4 carbamoyl-phosphate synthase (glutamine-hydrolysing) (subunit 2/2) (EC 6.3.5.5) from Halomonas eurihalina
PFams: CPSase_sm_chain, GATase, Peptidase_C26
Heteromeric, 381 amino acids: PaperBLAST, CDD, BRENDA::Q8RSS4
70% identical to

b0032 carbamoyl phosphate synthetase subunit α (EC 6.3.5.5) from Escherichia coli K-12 substr. MG1655
P0A6F1 carbamoyl-phosphate synthetase small subunit (EC 6.3.5.5) from Escherichia coli (strain K12)
CARA_ECOLI / P0A6F1 Carbamoyl-phosphate synthase small chain; Carbamoyl-phosphate synthetase glutamine chain; EC 6.3.5.5 from Escherichia coli (strain K12)
PFams: CPSase_sm_chain, GATase, Peptidase_C26
Heteromeric, 382 amino acids: PaperBLAST, CDD

PYR1_SQUAC / Q91437 CAD protein; EC 6.3.5.5; EC 2.1.3.2; EC 3.5.2.3 from Squalus acanthias (Spiny dogfish)
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, Dala_Dala_lig_C, CPSase_L_D3, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, MGS, Amidohydro_1, OTCace_N, OTCace
2242 amino acids: PaperBLAST, CDD, SwissProt::Q91437
50% identical to

P07258 carbamoyl phosphate synthetase (EC 6.3.5.5) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CARA_YEAST / P07258 Carbamoyl-phosphate synthase arginine-specific small chain; CPS-A; Arginine-specific carbamoyl-phosphate synthetase, glutamine chain; EC 6.3.5.5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: CPSase_sm_chain, GATase
Heteromeric, 411 amino acids: PaperBLAST, CDD

CH_122562 protein pyrABCN [Includes glutamine-dependent carbamoyl-phosphate; Aspartate carbamoyltransferase]; EC 2.1.3.2; EC 6.3.5.5 from Emericella nidulans
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, Dala_Dala_lig_C, CPSase_L_D3, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, MGS, OTCace_N, OTCace
2275 amino acids: PaperBLAST, CDD, CharProtDB::CH_122562
47% identical to

CARA_SCHPO / O60060 Carbamoyl-phosphate synthase arginine-specific small chain; CPS-A; Arginine-specific carbamoyl-phosphate synthetase, glutamine chain; EC 6.3.5.5 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
GI|3116139 arginine specific carbamoyl-phosphate synthase subunit Arg5 (predicted) from Schizosaccharomyces pombe
PFams: CPSase_sm_chain, GATase
415 amino acids: PaperBLAST, CDD

PYR1_CAEEL / Q18990 CAD protein; EC 6.3.5.5; EC 2.1.3.2; EC 3.5.2.3 from Caenorhabditis elegans
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, Dala_Dala_lig_C, CPSase_L_D3, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, MGS, Amidohydro_1, OTCace_N, OTCace
2198 amino acids: PaperBLAST, CDD, SwissProt::Q18990
44% identical to

PYR1_MESAU / P08955 CAD protein; EC 6.3.5.5; EC 2.1.3.2; EC 3.5.2.3 from Mesocricetus auratus (Golden hamster)
P08955 dihydroorotase (EC 3.5.2.3) from Mesocricetus auratus
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, CPSase_L_D3, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, MGS, Amidohydro_1, OTCace_N, OTCace
2225 amino acids: PaperBLAST, CDD, BRENDA::P08955
43% identical to

P25993 pyrimidine-specific carbamoyl-phosphate synthetase (small subunit, glutaminase subunit) (EC 6.3.5.5) from Bacillus subtilis (strain 168)
CARA_BACSU / P25993 Carbamoyl-phosphate synthase pyrimidine-specific small chain; Carbamoyl-phosphate synthetase glutamine chain; EC 6.3.5.5 from Bacillus subtilis (strain 168)
PFams: CPSase_sm_chain, GATase
Heteromeric, 364 amino acids: PaperBLAST, CDD

P27708 CAD protein (EC 3.5.2.3; EC 6.3.5.5; EC 2.1.3.2) from Homo sapiens
PYR1_HUMAN / P27708 CAD protein; EC 6.3.5.5; EC 2.1.3.2; EC 3.5.2.3 from Homo sapiens (Human)
P27708 aspartate carbamoyltransferase (EC 2.1.3.2); dihydroorotase (EC 3.5.2.3); carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Homo sapiens
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, CPSase_L_D3, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, MGS, Amidohydro_1, OTCace_N, OTCace
2225 amino acids: PaperBLAST, CDD, BRENDA::P27708
46% identical to

O15830 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Trypanosoma cruzi
PFams: CPSase_sm_chain, GATase, Peptidase_C26, CPSase_L_D2, CPSase_L_D3, ATP-grasp, CPSase_L_D2
1524 amino acids: PaperBLAST, CDD, BRENDA::O15830
46% identical to

P31327 ammonia-dependent carbamoyl-phosphate synthase (EC 6.3.4.16) from Homo sapiens
CPSM_HUMAN / P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial; Carbamoyl-phosphate synthetase I; CPSase I; EC 6.3.4.16 from Homo sapiens (Human)
P31327 carbamoyl-phosphate synthase (ammonia) (EC 6.3.4.16) from Homo sapiens
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, CPSase_L_D3, CPSase_L_D2, ATP-grasp, MGS
1500 amino acids: PaperBLAST, CDD, BRENDA::P31327
46% identical to

P07259 carbamoyl phosphate synthase/aspartate carbamoyltransferase (EC 2.1.3.2; EC 6.3.5.5) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
PYR1_YEAST / P07259 Protein URA2; EC 6.3.5.5; EC 2.1.3.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, Dala_Dala_lig_C, CPSase_L_D3, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, ATPgrasp_Ter, MGS, OTCace_N, OTCace
2214 amino acids: PaperBLAST, CDD, SwissProt::P07259
45% identical to

CPSM_MOUSE / Q8C196 Carbamoyl-phosphate synthase [ammonia], mitochondrial; Carbamoyl-phosphate synthetase I; CPSase I; EC 6.3.4.16 from Mus musculus (Mouse)
Q8C196 carbamoyl-phosphate synthase (ammonia) (EC 6.3.4.16) from Mus musculus
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, CPSase_L_D3, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, MGS
1500 amino acids: PaperBLAST, CDD, BRENDA::Q8C196
46% identical to

PYR1_SCHPO / Q09794 Protein ura1; EC 6.3.5.5; EC 2.1.3.2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
RF|NP_593055.1 carbamoyl-phosphate synthase (glutamine hydrolyzing), aspartate carbamoyltransferase Ura1; EC 2.1.3.2; EC 3.5.2.3; EC 6.3.5.5 from Schizosaccharomyces pombe
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, Dala_Dala_lig_C, CPSase_L_D3, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, MGS, OTCace_N, OTCace
2244 amino acids: PaperBLAST, CDD, CharProtDB::CH_125552
44% identical to

CPSM_RAT / P07756 Carbamoyl-phosphate synthase [ammonia], mitochondrial; Carbamoyl-phosphate synthetase I; CPSase I; EC 6.3.4.16 from Rattus norvegicus (Rat)
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, CPSase_L_D3, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, MGS
1500 amino acids: PaperBLAST, CDD, SwissProt::P07756
46% identical to

PYR1_DROME / P05990 CAD protein; Protein rudimentary; EC 6.3.5.5; EC 2.1.3.2; EC 3.5.2.3 from Drosophila melanogaster (Fruit fly)
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, Dala_Dala_lig_C, CPSase_L_D3, ATP-grasp, Dala_Dala_lig_C, CPSase_L_D2, MGS, Amidohydro_1, OTCace_N, OTCace
2224 amino acids: PaperBLAST, CDD, SwissProt::P05990
45% identical to

O15829 carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) from Leishmania mexicana
PFams: CPSase_sm_chain, GATase, CPSase_L_D2, CPSase_L_D3, CPSase_L_D2, ATP-grasp, Dala_Dala_lig_C, MGS
1520 amino acids: PaperBLAST, CDD, BRENDA::O15829
44% identical to