Other Characterized Proteins Similar to gatA

Finding the characterized proteins for gatA (aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A) in L-asparagine biosynthesis

Or see clustering for step gatA

Or see all steps for L-asparagine biosynthesis

Or cluster curated proteins matching a keyword

Definition of gatA

• HMM TIGR00132
• Curated proteins matching aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A
• Curated proteins matching glutamyl-tRNA(Gln) amidotransferase subunit A
• Curated sequence MONOMER-13955: Glutamyl-tRNA(Gln) amidotransferase subunit A; Glu-ADT subunit A; EC 6.3.5.7. glutamyl-tRNA^Gln amidotransferase subunit A (EC 6.3.5.7)
• Ignore hits to items matching EC 6.3.5.7 when looking for 'other' hits
• Comment: The amidotransferase often acts on both glutamyl-tRNA(Gln) and aspartyl-tRNA(Asn) -- do not try to distinguish. Note there are no hits for some of these terms -- for some reason only gatB is annotated as a aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit Need to flag the metacyc entries separately because they have HTML tags in their descriptions

Fetched 4 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 4 other characterized sequences. (Found 8 hits including self hits.)

Removing ignored items reduces this to 0 close sequences.

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for gatA.)

Q9CZN8 glutaminyl-tRNA synthase (glutamine-hydrolysing) (EC 6.3.5.7) from Mus musculus
PFams: Amidase
525 amino acids: PaperBLAST, CDD, BRENDA::Q9CZN8
88% identical to

GATA_HUMAN / Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Glu-AdT subunit A; Glutaminyl-tRNA synthase-like protein 1; EC 6.3.5.7 from Homo sapiens (Human)
Q9H0R6 glutaminyl-tRNA synthase (glutamine-hydrolysing) (EC 6.3.5.7) from Homo sapiens
PFams: Amidase
Heteromeric, 528 amino acids: PaperBLAST, CDD

P63488 glutaminyl-tRNA synthase (glutamine-hydrolysing) (subunit 2/2) (EC 6.3.5.7) from Staphylococcus aureus
PFams: Amidase
Heteromeric, 485 amino acids: PaperBLAST, CDD, BRENDA::P63488
63% identical to

O06491 glutamyl-tRNA^Gln amidotransferase subunit A (EC 6.3.5.7) from Bacillus subtilis (strain 168)
GATA_BACSU / O06491 Glutamyl-tRNA(Gln) amidotransferase subunit A; Glu-ADT subunit A; EC 6.3.5.7 from Bacillus subtilis (strain 168)
PFams: Amidase
Heteromeric, 485 amino acids: PaperBLAST, CDD

Q9X0Z9 glutaminyl-tRNA synthase (glutamine-hydrolysing) (EC 6.3.5.7) from Thermotoga maritima
PFams: Amidase
475 amino acids: PaperBLAST, CDD, BRENDA::Q9X0Z9
52% identical to

O06491 glutamyl-tRNA^Gln amidotransferase subunit A (EC 6.3.5.7) from Bacillus subtilis (strain 168)
GATA_BACSU / O06491 Glutamyl-tRNA(Gln) amidotransferase subunit A; Glu-ADT subunit A; EC 6.3.5.7 from Bacillus subtilis (strain 168)
PFams: Amidase
Heteromeric, 485 amino acids: PaperBLAST, CDD

Q9RTA9 glutamyl-tRNA^Gln amidotransferase subunit A (EC 6.3.5.7; EC 6.3.5.6) from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)
PFams: Amidase
Heteromeric, 482 amino acids: PaperBLAST, CDD, metacyc::MONOMER-14049
51% identical to

O06491 glutamyl-tRNA^Gln amidotransferase subunit A (EC 6.3.5.7) from Bacillus subtilis (strain 168)
GATA_BACSU / O06491 Glutamyl-tRNA(Gln) amidotransferase subunit A; Glu-ADT subunit A; EC 6.3.5.7 from Bacillus subtilis (strain 168)
PFams: Amidase
Heteromeric, 485 amino acids: PaperBLAST, CDD