Other Characterized Proteins Similar to fbp

GapMind for Amino acid biosynthesis

Other Characterized Proteins Similar to fbp

Finding the characterized proteins for fbp (6-deoxy-5-ketofructose 1-phosphate synthase) in chorismate biosynthesis

Or see clustering for step fbp

Or see all steps for chorismate biosynthesis

Or cluster curated proteins matching a keyword

Definition of fbp

Curated proteins or TIGRFams with EC 2.2.1.11
Curated proteins or TIGRFams with EC 4.1.2.13
Ignore hits to MONOMER-14592 when looking for 'other' hits (2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase (EC 2.2.1.10). 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; ADH synthase; ADHS; ADTH synthase; Transaldolase-like ADHS; EC 2.2.1.10. 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase monomer (EC 4.1.2.13; EC 2.2.1.10))
Ignore hits to items matching fructose%bisphosphate aldolase when looking for 'other' hits
Ignore hits to P84722 when looking for 'other' hits (Putative fructose-bisphosphate aldolase, chloroplastic; PS6; EC 4.1.2.13)
Ignore hits to P86979 when looking for 'other' hits (Fructose-bisphosphate aldolase A; Muscle-type aldolase; Allergen Thu a 3.0101; EC 4.1.2.13)
Ignore hits to P86980 when looking for 'other' hits (Fructose-bisphosphate aldolase A; Muscle-type aldolase; Allergen Gad m 3.0101; EC 4.1.2.13)
Ignore hits to Q980K6 when looking for 'other' hits (fructose-bisphosphate aldolase (EC 4.1.2.13))
Ignore hits to A3MSD2 when looking for 'other' hits (fructose-bisphosphatase (EC 3.1.3.11); fructose-bisphosphate aldolase (EC 4.1.2.13))
Ignore hits to Q8NKR9 when looking for 'other' hits (fructose-bisphosphatase (EC 3.1.3.11). Fructose-1,6-bisphosphate aldolase/phosphatase; FBP A/P; FBP aldolase/phosphatase; Fructose-1,6-bisphosphatase; FBPase; EC 3.1.3.11; EC 4.1.2.13)
Ignore hits to A0RV30 when looking for 'other' hits (Fructose-1,6-bisphosphate aldolase/phosphatase; FBP A/P; FBP aldolase/phosphatase; EC 3.1.3.11; EC 4.1.2.13)
Ignore hits to A4YIZ5 when looking for 'other' hits (Fructose-1,6-bisphosphate aldolase/phosphatase; FBP A/P; FBP aldolase/phosphatase; EC 3.1.3.11; EC 4.1.2.13)
Ignore hits to A8A9E4 when looking for 'other' hits (Fructose-1,6-bisphosphate aldolase/phosphatase; FBP A/P; FBP aldolase/phosphatase; EC 3.1.3.11; EC 4.1.2.13. fructose-1,6-bisphosphate aldolase/phosphatase (EC 4.1.2.13; EC 3.1.3.11))
Ignore hits to B1YAL1 when looking for 'other' hits (Fructose-1,6-bisphosphate aldolase/phosphatase; FBP A/P; FBP aldolase/phosphatase; EC 3.1.3.11; EC 4.1.2.13. fructose-bisphosphatase (EC 3.1.3.11); fructose-bisphosphate aldolase (EC 4.1.2.13))
Ignore hits to B6YTP6 when looking for 'other' hits (Fructose-1,6-bisphosphate aldolase/phosphatase; FBP A/P; FBP aldolase/phosphatase; EC 3.1.3.11; EC 4.1.2.13)
Ignore hits to D9PUH5 when looking for 'other' hits (Fructose-1,6-bisphosphate aldolase/phosphatase; FBP A/P; FBP aldolase/phosphatase; EC 3.1.3.11; EC 4.1.2.13)
Ignore hits to F9VMT6 when looking for 'other' hits (Fructose-1,6-bisphosphate aldolase/phosphatase; FBP A/P; FBP aldolase/phosphatase; Fructose-1,6-bisphosphatase; FBPase; EC 3.1.3.11; EC 4.1.2.13. fructose-bisphosphatase (EC 3.1.3.11); fructose-bisphosphate aldolase (EC 4.1.2.13))
Ignore hits to Q2RG86 when looking for 'other' hits (Fructose-1,6-bisphosphate aldolase/phosphatase; FBP A/P; FBP aldolase/phosphatase; EC 3.1.3.11; EC 4.1.2.13)
Ignore hits to Q72K02 when looking for 'other' hits (Fructose-1,6-bisphosphate aldolase/phosphatase; FBP A/P; FBP aldolase/phosphatase; EC 3.1.3.11; EC 4.1.2.13)
Comment: 6-deoxy-5-ketofructose-1-phosphate synthase is an activity of some fructose-bisphosphate aldolases (which are usually annotated as 4.1.2.13). To find the fbp in Desulfovibrio vulgaris Hildenborough and Miyazaki F, it is necessary to match more broadly. MetaCyc reports that AroA' from Methanococcus jannaschii (link) also has activity as a fructose-bisphosphate aldolase, but it's not clear that it carries out this reaction. The bifunctional fructose-1,6-bisphosphate aldolase/phosphatases are ignored because it is not obvious that they would carry out this reaction; this includes Q980K6, A3MSD2, Q8NKR9, A0RV30, A4YIZ5, A8A9E4, B1YAL1, B6YTP6, D9PUH5, F9VMT6, Q2RG86, Q72K02. And ignore CharProtDB items with incorrect EC and very short SwissProt entries.

Fetched 77 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 9 other characterized sequences. (Found 86 hits including self hits.)

Removing ignored items reduces this to 8 close sequences.

There are also 1 HMM-only high-coverage hits.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for fbp.)

Q65EY6 D-tagatose-bisphosphate aldolase (EC 4.1.2.40) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)
PFams: F_bP_aldolase
283 amino acids: PaperBLAST, CDD, metacyc::MONOMER-21831
45% identical to

Q5HE75 fructose-bisphosphate aldolase (EC 4.1.2.13) from Staphylococcus aureus
PFams: F_bP_aldolase
286 amino acids: PaperBLAST, CDD

GATY_KLEOX / Q8VS16 D-tagatose-1,6-bisphosphate aldolase subunit GatY; TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase; EC 4.1.2.40 from Klebsiella oxytoca
Q8VS16 tagatose-bisphosphate aldolase (EC 4.1.2.40) from Klebsiella oxytoca
PFams: F_bP_aldolase
284 amino acids: PaperBLAST, CDD, SwissProt::Q8VS16
43% identical to

I3EBM6 fructose-bisphosphate aldolase (EC 4.1.2.13) from Bacillus methanolicus
PFams: F_bP_aldolase
285 amino acids: PaperBLAST, CDD

GATY_ECOLX / P0C8J7 D-tagatose-1,6-bisphosphate aldolase subunit GatY; TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase; EC 4.1.2.40 from Escherichia coli
PFams: F_bP_aldolase
284 amino acids: PaperBLAST, CDD, SwissProt::P0C8J7
42% identical to

ALF_BACSU / P13243 Probable fructose-bisphosphate aldolase; FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase; EC 4.1.2.13 from Bacillus subtilis (strain 168)
PFams: F_bP_aldolase
285 amino acids: PaperBLAST, CDD

b2096 tagatose-1,6-bisphosphate aldolase 2 (EC 4.1.2.40) from Escherichia coli K-12 substr. MG1655
P0C8J6 tagatose-1,6-bisphosphate aldolase 2 (EC 4.1.2.40) from Escherichia coli (strain K12)
GATY_ECOLI / P0C8J6 D-tagatose-1,6-bisphosphate aldolase subunit GatY; TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase; EC 4.1.2.40 from Escherichia coli (strain K12)
PFams: F_bP_aldolase
284 amino acids: PaperBLAST, CDD, SwissProt::P0C8J6
42% identical to

Q5HE75 fructose-bisphosphate aldolase (EC 4.1.2.13) from Staphylococcus aureus
PFams: F_bP_aldolase
286 amino acids: PaperBLAST, CDD

KBAY_ECOLX / Q9KIP8 D-tagatose-1,6-bisphosphate aldolase subunit KbaY; TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Ketose 1,6-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase; EC 4.1.2.40 from Escherichia coli
PFams: F_bP_aldolase
286 amino acids: PaperBLAST, CDD, SwissProt::Q9KIP8
41% identical to

I3EBM6 fructose-bisphosphate aldolase (EC 4.1.2.13) from Bacillus methanolicus
PFams: F_bP_aldolase
285 amino acids: PaperBLAST, CDD

b3137 tagatose-1,6-bisphosphate aldolase 1 (EC 4.1.2.40) from Escherichia coli K-12 substr. MG1655
P0AB76 D-tagatose-1,6-bisphosphate aldolase subunit KbaY (EC 4.1.2.40) from Escherichia coli O157:H7
P0AB74 tagatose-1,6-bisphosphate aldolase 1 (EC 4.1.2.40) from Escherichia coli (strain K12)
KBAY_ECOLI / P0AB74 D-tagatose-1,6-bisphosphate aldolase subunit KbaY; TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Ketose 1,6-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase; EC 4.1.2.40 from Escherichia coli (strain K12)
RF|NP_417606 tagatose-bisphosphate aldolase; EC 4.1.2.40 from Escherichia coli K12
PFams: F_bP_aldolase
Heteromeric, 286 amino acids: PaperBLAST, CDD, CharProtDB::CH_024465
41% identical to

I3EBM6 fructose-bisphosphate aldolase (EC 4.1.2.13) from Bacillus methanolicus
PFams: F_bP_aldolase
285 amino acids: PaperBLAST, CDD

SQIA_ALKUR / A0A2P6MHY1 Sulfofructosephosphate aldolase; SFP aldolase; EC 4.1.2.57 from Alkalicoccus urumqiensis (Bacillus urumqiensis)
PFams: F_bP_aldolase
287 amino acids: PaperBLAST, CDD, SwissProt::A0A2P6MHY1
41% identical to

b1773 L-glycero-L-galacto-octuluronate-1-phosphate aldolase from Escherichia coli K-12 substr. MG1655
P77704 L-glycero-L-galacto-octuluronate-1-phosphate aldolase from Escherichia coli (strain K12)
PFams: F_bP_aldolase
278 amino acids: PaperBLAST, CDD, ecocyc::G6960-MONOMER
42% identical to

HMM-only sequences

(Since these sequences' annotations are outside the definition for fbp, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)

P42420 5-dehydro-2-deoxyphosphogluconate aldolase (EC 4.1.2.29) from Bacillus subtilis (strain 168)
IOLJ_BACSU / P42420 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase; DKGP aldolase; EC 4.1.2.29 from Bacillus subtilis (strain 168)
PFams: F_bP_aldolase
290 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for fbp.)

CH_091808 fructose-1,6-bisphosphate aldolase; EC 5.3.1.9 from Entamoeba histolytica HM-1:IMSS
PFams: F_bP_aldolase
330 amino acids: PaperBLAST, CDD, CharProtDB::CH_091808
45% identical to

ALF_GIAIC / A8B2U2 Fructose-bisphosphate aldolase; Glfba; glFBPA; Fructose-1,6-bisphosphate aldolase; EC 4.1.2.13 from Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia)
PFams: F_bP_aldolase
323 amino acids: PaperBLAST, CDD