GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for cysK (O-acetylserine sulfhydrylase) in L-cysteine biosynthesis

Or see other characterized proteins similar to cysK

Or see all steps for L-cysteine biosynthesis

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Definition of cysK

Fetched 54 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 53 of these sequences

Found 1 clusters of similar sequences. Another 3 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 299-456 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

A4HPM6 cysteine synthase (EC 2.5.1.47)
PFams: PALP
333 amino acids: PaperBLAST, CDD, Compare to cluster

A2GMG5 cysteine synthase (EC 2.5.1.47)
PFams: PALP
299 amino acids: PaperBLAST, CDD, Compare to cluster

A3RM03 cysteine synthase (EC 2.5.1.47)
PFams: PALP
325 amino acids: PaperBLAST, CDD, Compare to cluster

A3RM06 cysteine synthase (EC 2.5.1.47)
PFams: PALP
324 amino acids: PaperBLAST, CDD, Compare to cluster

A8YBP8 cysteine synthase (EC 2.5.1.47)
PFams: PALP
315 amino acids: PaperBLAST, CDD, Compare to cluster

A8YBS4 cysteine synthase (EC 2.5.1.47)
PFams: PALP
319 amino acids: PaperBLAST, CDD, Compare to cluster

C4ITG6 cysteine synthase (EC 2.5.1.47)
PFams: PALP
334 amino acids: PaperBLAST, CDD, Compare to cluster

D2Z027 O-ureido-L-serine synthase; Cysteine synthase homolog DscD; O-acetylserine sulfhydrylase; EC 2.6.99.3; EC 2.5.1.47
D2Z027 cysteine synthase (EC 2.5.1.47); O-ureido-L-serine synthase (EC 2.6.99.3)
MONOMER-18016 O-ureido-L-serine synthase (EC 2.5.1.47; EC 2.6.99.3)
PFams: PALP
324 amino acids: PaperBLAST, CDD, Compare to cluster

E5LPF4 cysteine synthase (EC 2.5.1.47)
PFams: PALP
309 amino acids: PaperBLAST, CDD, Compare to cluster

F4K5T2 Bifunctional cystathionine gamma-lyase/cysteine synthase; Beta-substituted Ala synthase 4;3; ARAth-Bsas4;3; L-cysteine desulfhydrase 1; DES1; O-acetylserine (thiol)-lyase; OASTL; Protein CS-LIKE; EC 2.5.1.47; EC 4.4.1.1
F4K5T2 L-cysteine desulfidase (EC 4.4.1.28)
PFams: PALP
323 amino acids: PaperBLAST, CDD, Compare to cluster

I1L6I6 L-3-cyanoalanine synthase (EC 4.4.1.9) (from HMM only)
PFams: PALP
373 amino acids: PaperBLAST, CDD, Compare to cluster

J9WJN8 L-cysteine desulfidase (EC 4.4.1.28) (from HMM only)
PFams: PALP
323 amino acids: PaperBLAST, CDD, Compare to cluster

O15570 cysteine synthase (EC 2.5.1.47)
PFams: PALP
337 amino acids: PaperBLAST, CDD, Compare to cluster

O15635 cysteine synthase (EC 2.5.1.47)
PFams: PALP
337 amino acids: PaperBLAST, CDD, Compare to cluster

O22682 Probable S-sulfocysteine synthase, chloroplastic; Beta-substituted Ala synthase 5;1; ARAth-Bsas5;1; CS26; O-acetylserine sulfhydrylase; EC 2.5.1.47
O22682 cysteine synthase (EC 2.5.1.47)
PFams: PALP
404 amino acids: PaperBLAST, CDD, Compare to cluster

O45679 Bifunctional L-3-cyanoalanine synthase/cysteine synthase; CAS; O-acetylserine (thiol)-lyase 2; OAS-TL; EC 2.5.1.47; EC 4.4.1.9
O45679 cysteine synthase (EC 2.5.1.47)
PFams: PALP
337 amino acids: PaperBLAST, CDD, Compare to cluster

O81154 cysteine synthase (EC 2.5.1.47)
PFams: PALP
325 amino acids: PaperBLAST, CDD, Compare to cluster

O81155 cysteine synthase (EC 2.5.1.47)
PFams: PALP
386 amino acids: PaperBLAST, CDD, Compare to cluster

P0A1E3 Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine sulfhydrylase A; EC 2.5.1.47
P0A1E3 cysteine synthase (EC 2.5.1.47)
PFams: PALP
323 amino acids: PaperBLAST, CDD, Compare to cluster

ACSERLYA-MONOMER O-acetylserine sulfhydrylase A (EC 2.5.1.47; EC 4.4.1.1; EC 4.4.1.28)
P0ABK5 Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine sulfhydrylase A; S-carboxymethylcysteine synthase; Sulfate starvation-induced protein 5; SSI5; EC 2.5.1.47; EC 4.5.1.5
P0ABK5 cysteine synthase (EC 2.5.1.47)
CH_024343 cysteine synthase A
PFams: PALP
323 amino acids: PaperBLAST, CDD, Compare to cluster

ACSERLYB-MONOMER cysteine synthase B (EC 2.5.1.144; EC 2.5.1.47; EC 4.4.1.1; EC 4.4.1.28)
P16703 Cysteine synthase B; CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B; EC 2.5.1.47
P16703 cysteine synthase (EC 2.5.1.47)
ACSERLYB-MONOMER cysteine synthase B (EC 2.5.1.47)
PFams: PALP
303 amino acids: PaperBLAST, CDD, Compare to cluster

P29848 cysteine synthase (EC 2.5.1.47)
PFams: PALP
303 amino acids: PaperBLAST, CDD, Compare to cluster

P37887 Cysteine synthase; CSase; O-acetylserine (thiol)-lyase; OAS-TL; Superoxide-inducible protein 11; SOI11; EC 2.5.1.47
P37887 cysteine synthase (EC 2.5.1.47)
PFams: PALP
308 amino acids: PaperBLAST, CDD, Compare to cluster

P45040 cysteine synthase (EC 2.5.1.47)
PFams: PALP
316 amino acids: PaperBLAST, CDD, Compare to cluster

P47998 Cysteine synthase 1; At.OAS.5-8; Beta-substituted Ala synthase 1;1; ARAth-Bsas1;1; CSase A; AtCS-A; Cys-3A; O-acetylserine (thiol)-lyase 1; OAS-TL A; O-acetylserine sulfhydrylase; Protein ONSET OF LEAF DEATH 3; EC 2.5.1.47
P47998 cysteine synthase (EC 2.5.1.47)
PFams: PALP
322 amino acids: PaperBLAST, CDD, Compare to cluster

P47999 Cysteine synthase, chloroplastic/chromoplastic; At.OAS.7-4; Beta-substituted Ala synthase 2;1; ARAth-Bsas2;1; CSase B; AtCS-B; CS-B; O-acetylserine (thiol)-lyase; O-acetylserine sulfhydrylase; OAS-TL B; cpACS1; EC 2.5.1.47
P47999 cysteine synthase (EC 2.5.1.47)
PFams: PALP
392 amino acids: PaperBLAST, CDD, Compare to cluster

P9WP53 O-phosphoserine sulfhydrylase; OPS sulfhydrylase; CysO-thiocarboxylate-dependent cysteine synthase; Cysteine synthase B; CSase B; O-phosphoserine-specific cysteine synthase; [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase; EC 2.5.1.113 (from HMM only)
P9WP53 [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase (EC 2.5.1.113); O-phosphoserine sulfhydrylase (EC 2.5.1.65)
PFams: PALP
323 amino acids: PaperBLAST, CDD, Compare to cluster

P9WP55 O-acetylserine sulfhydrylase; OAS sulfhydrylase; OASS; Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine-specific cysteine synthase; Sulfide-dependent cysteine synthase; EC 2.5.1.47
P9WP55 cysteine synthase (EC 2.5.1.47)
PFams: PALP
310 amino acids: PaperBLAST, CDD, Compare to cluster

Q1KLZ1 L-3-cyanoalanine synthase 2, mitochondrial; MdCAS2; EC 4.4.1.9
Q1KLZ1 L-3-cyanoalanine synthase (EC 4.4.1.9)
MONOMER-16251 β-cyanoalanine synthase (EC 4.4.1.9) (from HMM only)
PFams: PALP
375 amino acids: PaperBLAST, CDD, Compare to cluster

Q1KLZ2 L-3-cyanoalanine synthase 1, mitochondrial; MdCAS1; EC 4.4.1.9
Q1KLZ2 L-3-cyanoalanine synthase (EC 4.4.1.9)
MONOMER-16250 β-cyanoalanine synthase (EC 4.4.1.9) (from HMM only)
PFams: PALP
376 amino acids: PaperBLAST, CDD, Compare to cluster

Q2PZM5 cysteine synthase (EC 2.5.1.47)
PFams: PALP
319 amino acids: PaperBLAST, CDD, Compare to cluster

Q401L7 cysteine synthase (EC 2.5.1.47)
PFams: PALP
336 amino acids: PaperBLAST, CDD, Compare to cluster

Q43153 Bifunctional L-3-cyanoalanine synthase/cysteine synthase, mitochondrial; Beta-cyanoalanine synthase; SoCAS; Beta-substituted Ala synthase 3-1; SPIol-Bsas3-1; Cysteine synthase C; EC 2.5.1.47; EC 4.4.1.9
Q43153 L-3-cyanoalanine synthase (EC 4.4.1.9)
PFams: PALP
368 amino acids: PaperBLAST, CDD, Compare to cluster

Q76MX2 Bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial; EC 2.5.1.47; EC 4.4.1.9
Q76MX2 L-3-cyanoalanine synthase (EC 4.4.1.9)
PFams: PALP
351 amino acids: PaperBLAST, CDD, Compare to cluster

Q84IF9 cysteine synthase (EC 2.5.1.47); L-3-cyanoalanine synthase (EC 4.4.1.9)
PFams: PALP
308 amino acids: PaperBLAST, CDD, Compare to cluster

Q8L0X3 L-cysteine desulfidase (EC 4.4.1.28)
MONOMER-10304 L-cysteine desulfhydrase (from HMM only)
PFams: PALP
306 amino acids: PaperBLAST, CDD, Compare to cluster

Q93244 Cysteine synthase 1; O-acetylserine (thiol)-lyase 1; OAS-TL; EC 2.5.1.47
Q93244 cysteine synthase (EC 2.5.1.47)
PFams: PALP
341 amino acids: PaperBLAST, CDD, Compare to cluster

Q9FS29 Bifunctional L-3-cyanoalanine synthase/cysteine synthase 2, mitochondrial; EC 2.5.1.47; EC 4.4.1.9
Q9FS29 L-3-cyanoalanine synthase (EC 4.4.1.9)
PFams: PALP
347 amino acids: PaperBLAST, CDD, Compare to cluster

Q9S757 Bifunctional L-3-cyanoalanine synthase/cysteine synthase C1, mitochondrial; Beta-substituted Ala synthase 3;1; ARAth-Bsas3;1; Cysteine synthase C1; AtCYSC1; O-acetylserine (thiol)-lyase 5; EC 2.5.1.47; EC 4.4.1.9
Q9S757 L-3-cyanoalanine synthase (EC 4.4.1.9)
PFams: PALP
368 amino acids: PaperBLAST, CDD, Compare to cluster

W5S3I4 cysteine synthase (EC 2.5.1.47)
PFams: PALP
325 amino acids: PaperBLAST, CDD, Compare to cluster

P50867 Cysteine synthase 1; CS 1; O-acetylserine (thiol)-lyase 1; OAS-TL 1; O-acetylserine sulfhydrylase 1; O-succinylserine sulfhydrylase; EC 2.5.1.-; EC 2.5.1.47
CH_013302 cysteine synthase; EC 2.5.1.47
PFams: PALP
370 amino acids: PaperBLAST, CDD, Compare to cluster

P87131 Cysteine synthase 2; CS 2; Cysteine synthase-like protein; CSl; O-acetylserine (thiol)-lyase 2; OAS-TL 2; O-acetylserine sulfhydrylase 2; EC 2.5.1.47
CH_124419 cysteine synthase Cys12; EC 2.5.1.47
PFams: PALP
395 amino acids: PaperBLAST, CDD, Compare to cluster

O59701 Cysteine synthase 1; CS 1; O-acetylserine (thiol)-lyase 1; OAS-TL 1; O-acetylserine sulfhydrylase 1; O-succinylserine sulfhydrylase; EC 2.5.1.-; EC 2.5.1.47
CH_124760 cysteine synthase
PFams: PALP
351 amino acids: PaperBLAST, CDD, Compare to cluster

O01592 Cysteine synthase 3; O-acetylserine (thiol)-lyase 3; OAS-TL; EC 2.5.1.47
PFams: PALP
337 amino acids: PaperBLAST, CDD, Compare to cluster

P53206 Putative cysteine synthase; CS; Cysteine synthase-like protein; CSl; O-acetylserine (thiol)-lyase; OAS-TL; O-acetylserine sulfhydrylase; EC 2.5.1.47
PFams: PALP
393 amino acids: PaperBLAST, CDD, Compare to cluster

Q43317 Cysteine synthase; CSase; Beta-PA/CSase; Beta-pyrazolylalanine synthase; L-mimosine synthase; O-acetylserine (thiol)-lyase; OAS-TL; O-acetylserine sulfhydrylase; EC 2.5.1.47; EC 2.5.1.51; EC 4.2.1.50; EC 2.5.1.52
PFams: PALP
325 amino acids: PaperBLAST, CDD, Compare to cluster

Q59966 Cysteine synthase; CSase; O-acetylserine (thiol)-lyase; OAS-TL; O-acetylserine sulfhydrylase; EC 2.5.1.47
PFams: PALP
329 amino acids: PaperBLAST, CDD, Compare to cluster

Q7RYW6 Cysteine synthase 1; CS 1; O-acetylserine (thiol)-lyase 1; OAS-TL 1; O-acetylserine sulfhydrylase 1; O-succinylserine sulfhydrylase; EC 2.5.1.-; EC 2.5.1.47
PFams: PALP
376 amino acids: PaperBLAST, CDD, Compare to cluster

Q7SHQ1 Cysteine synthase 2; CS 2; Cysteine synthase-like protein; CSl; O-acetylserine (thiol)-lyase 2; OAS-TL 2; O-acetylserine sulfhydrylase 2; EC 2.5.1.47
PFams: PALP
456 amino acids: PaperBLAST, CDD, Compare to cluster

Q9S6Z7 Bifunctional L-3-cyanoalanine synthase/cysteine synthase D1; Beta-substituted Ala synthase 4;1; ARAth-Bsas4;1; Cysteine synthase D1; AtcysD1; O-acetylserine (thiol)-lyase 3; EC 2.5.1.47; EC 4.4.1.9
PFams: PALP
324 amino acids: PaperBLAST, CDD, Compare to cluster

Q9SXS7 Bifunctional L-3-cyanoalanine synthase/cysteine synthase D2; Beta-substituted Ala synthase 4;2; ARAth-Bsas4;2; Cysteine synthase D2; AtcysD2; O-acetylserine (thiol)-lyase 6; EC 2.5.1.47; EC 4.4.1.9
PFams: PALP
323 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/3 heteromeric)

Q43725 Cysteine synthase, mitochondrial; Beta-substituted Ala synthase 2;2; ARAth-Bsas2;2; CSase C; AtCS-C; CS-C; O-acetylserine (thiol)-lyase; O-acetylserine sulfhydrylase; OAS-TL C; EC 2.5.1.47
Q43725 cysteine synthase (EC 2.5.1.47)
PFams: PALP
430 amino acids: PaperBLAST, CDD
(similar to BRENDA::O81155 from Cluster 1, but similarity to seed sequence is below thresholds)

Q9YBL2 Protein CysO; Cystathionine beta-synthase; Cysteine synthase; O-acetylserine sulfhydrylase; O-phosphoserine sulfhydrylase; Serine sulfhydrase; EC 4.2.1.22; EC 2.5.1.47; EC 2.5.1.65
Q9YBL2 cysteine synthase (EC 2.5.1.47); O-phosphoserine sulfhydrylase (EC 2.5.1.65)
PFams: PALP
389 amino acids: PaperBLAST, CDD
(similar to BRENDA::P29848 from Cluster 1, but similarity to seed sequence is below thresholds)

P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49
YLR303W-MONOMER Met17 (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD