Other Characterized Proteins Similar to cysK

GapMind for Amino acid biosynthesis

Other Characterized Proteins Similar to cysK

Finding the characterized proteins for cysK (O-acetylserine sulfhydrylase) in L-cysteine biosynthesis

Or see clustering for step cysK

Or see all steps for L-cysteine biosynthesis

Or cluster curated proteins matching a keyword

Definition of cysK

Curated proteins or TIGRFams with EC 2.5.1.47
Comment: E. coli also has cysM (same EC number)

Fetched 54 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 23 other characterized sequences. (Found 77 hits including self hits.)

There are also 6 HMM-only high-coverage hits.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for cysK.)

CH_123612 O-acetylhomoserine O-acetylserine sulphydrylase
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
440 amino acids: PaperBLAST, CDD, CharProtDB::CH_123612
69% identical to

YLR303W-MONOMER Met17 (EC 2.5.1.49)
P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

P50125 Homocysteine synthase; O-acetylhomoserine sulfhydrylase; OAH SHL; OAH sulfhydrylase; EC 2.5.1.49
CH_122447 O-acetylhomoserine (thiol)-lyase; EC 2.5.1.49
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Beta_elim_lyase, Aminotran_1_2, Aminotran_5
437 amino acids: PaperBLAST, CDD, CharProtDB::CH_122447
64% identical to

O13326 Homocysteine synthase; O-acetylhomoserine sulfhydrylase; OAH SHL; OAH sulfhydrylase; EC 2.5.1.49
CH_124469 homocysteine synthase Met17; EC 2.5.1.49
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
429 amino acids: PaperBLAST, CDD, CharProtDB::CH_124469
63% identical to

W7MS09 Sulfhydrylase FUB7; Fusaric acid biosynthesis protein 7; EC 2.5.1.-
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
433 amino acids: PaperBLAST, CDD, SwissProt::W7MS09
57% identical to

A0A0D2YG02 Sulfhydrylase FUB7; Fusaric acid biosynthesis protein 7; EC 2.5.1.-
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
433 amino acids: PaperBLAST, CDD, SwissProt::A0A0D2YG02
57% identical to

S0DUX5 Sulfhydrylase FUB7; Fusaric acid biosynthesis protein 7; EC 2.5.1.-
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
433 amino acids: PaperBLAST, CDD, SwissProt::S0DUX5
57% identical to

Q5SK88 O-acetyl-L-homoserine sulfhydrylase 1; OAH-sulfhydrylase 1; EC 2.5.1.-
Q93I77 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2
421 amino acids: PaperBLAST, CDD, BRENDA::Q93I77
50% identical to

L7N4M1 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP
449 amino acids: PaperBLAST, CDD, BRENDA::L7N4M1
48% identical to

Q9EYM7 cystathionine beta-lyase (EC 4.4.1.8)
PFams: PALP, CBS
463 amino acids: PaperBLAST, CDD, BRENDA::Q9EYM7
48% identical to

Q84IF9 cysteine synthase (EC 2.5.1.47); L-3-cyanoalanine synthase (EC 4.4.1.9)
PFams: PALP
308 amino acids: PaperBLAST, CDD

Q8J0B2 Sulfhydrylase-like protein lolC1; Loline biosynthesis cluster 1 protein C; EC 2.5.1.-
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
473 amino acids: PaperBLAST, CDD, SwissProt::Q8J0B2
45% identical to

Q5MNH8 Sulfhydrylase-like protein lolC2; Loline biosynthesis cluster 2 protein C; EC 2.5.1.-
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Aminotran_5
473 amino acids: PaperBLAST, CDD, SwissProt::Q5MNH8
45% identical to

MONOMER-9366 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49)
P94890 O-acetyl-L-homoserine sulfhydrylase; OAH-sulfhydrylase; EC 2.5.1.-
P94890 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1
442 amino acids: PaperBLAST, CDD, BRENDA::P94890
45% identical to

CH_122414 cystathionine beta-synthase; EC 4.2.1.22
PFams: PALP, CBS
533 amino acids: PaperBLAST, CDD, CharProtDB::CH_122414
44% identical to

E5LPF4 cysteine synthase (EC 2.5.1.47)
PFams: PALP
309 amino acids: PaperBLAST, CDD

HP0107-MONOMER cystathionine β-synthase (EC 4.2.1.22)
PFams: PALP
306 amino acids: PaperBLAST, CDD, metacyc::HP0107-MONOMER
45% identical to

P37887 Cysteine synthase; CSase; O-acetylserine (thiol)-lyase; OAS-TL; Superoxide-inducible protein 11; SOI11; EC 2.5.1.47
P37887 cysteine synthase (EC 2.5.1.47)
PFams: PALP
308 amino acids: PaperBLAST, CDD

O05393 O-acetylserine dependent cystathionine beta-synthase; EC 2.5.1.134
PFams: PALP
307 amino acids: PaperBLAST, CDD, SwissProt::O05393
44% identical to

MONOMER-17873 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1
438 amino acids: PaperBLAST, CDD, metacyc::MONOMER-17873
43% identical to

Q9VRD9 cystathionine beta-synthase (EC 4.2.1.22)
PFams: PALP, CBS
522 amino acids: PaperBLAST, CDD, BRENDA::Q9VRD9
42% identical to

P9WP55 O-acetylserine sulfhydrylase; OAS sulfhydrylase; OASS; Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine-specific cysteine synthase; Sulfide-dependent cysteine synthase; EC 2.5.1.47
P9WP55 cysteine synthase (EC 2.5.1.47)
PFams: PALP
310 amino acids: PaperBLAST, CDD

MONOMER-8583 cystathionine β-synthase subunit (EC 4.2.1.22)
P32232 Cystathionine beta-synthase; Beta-thionase; Hemoprotein H-450; Serine sulfhydrase; EC 4.2.1.22
PFams: PALP, CBS
561 amino acids: PaperBLAST, CDD, SwissProt::P32232
43% identical to

Q2PZM5 cysteine synthase (EC 2.5.1.47)
PFams: PALP
319 amino acids: PaperBLAST, CDD

G18NG-10215-MONOMER O-acetylhomoserine sulfhydrylase (EC 2.5.1.49)
Q79VI4 O-acetyl-L-homoserine sulfhydrylase; OAH-sulfhydrylase; EC 2.5.1.49
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1
437 amino acids: PaperBLAST, CDD, SwissProt::Q79VI4
42% identical to

P35520 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22
P35520 cystathionine beta-synthase (EC 4.2.1.22)
PFams: PALP, CBS
551 amino acids: PaperBLAST, CDD, BRENDA::P35520
42% identical to

Q2PZM5 cysteine synthase (EC 2.5.1.47)
PFams: PALP
319 amino acids: PaperBLAST, CDD

Q7M844 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Aminotran_5
422 amino acids: PaperBLAST, CDD, BRENDA::Q7M844
40% identical to

P32582 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; Sulfur transfer protein 4; EC 4.2.1.22
P32582 cystathionine beta-synthase (EC 4.2.1.22)
PFams: PALP, CBS, CBS
507 amino acids: PaperBLAST, CDD, BRENDA::P32582
40% identical to

A8YBP8 cysteine synthase (EC 2.5.1.47)
PFams: PALP
315 amino acids: PaperBLAST, CDD

T1KF23 L-3-cyanoalanine synthase (EC 4.4.1.9)
PFams: PALP
320 amino acids: PaperBLAST, CDD, BRENDA::T1KF23
41% identical to

O81154 cysteine synthase (EC 2.5.1.47)
PFams: PALP
325 amino acids: PaperBLAST, CDD

HMM-only sequences

(Since these sequences' annotations are outside the definition for cysK, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)

P9WP53 O-phosphoserine sulfhydrylase; OPS sulfhydrylase; CysO-thiocarboxylate-dependent cysteine synthase; Cysteine synthase B; CSase B; O-phosphoserine-specific cysteine synthase; [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase; EC 2.5.1.113
P9WP53 [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase (EC 2.5.1.113); O-phosphoserine sulfhydrylase (EC 2.5.1.65)
PFams: PALP
323 amino acids: PaperBLAST, CDD

MONOMER-16251 β-cyanoalanine synthase (EC 4.4.1.9)
Q1KLZ1 L-3-cyanoalanine synthase 2, mitochondrial; MdCAS2; EC 4.4.1.9
Q1KLZ1 L-3-cyanoalanine synthase (EC 4.4.1.9)
PFams: PALP
375 amino acids: PaperBLAST, CDD

I1L6I6 L-3-cyanoalanine synthase (EC 4.4.1.9)
PFams: PALP
373 amino acids: PaperBLAST, CDD

J9WJN8 L-cysteine desulfidase (EC 4.4.1.28)
PFams: PALP
323 amino acids: PaperBLAST, CDD

MONOMER-16250 β-cyanoalanine synthase (EC 4.4.1.9)
Q1KLZ2 L-3-cyanoalanine synthase 1, mitochondrial; MdCAS1; EC 4.4.1.9
Q1KLZ2 L-3-cyanoalanine synthase (EC 4.4.1.9)
PFams: PALP
376 amino acids: PaperBLAST, CDD

MONOMER-10304 L-cysteine desulfhydrase
Q8L0X3 L-cysteine desulfidase (EC 4.4.1.28)
PFams: PALP
306 amino acids: PaperBLAST, CDD