GapMind for Amino acid biosynthesis

 

Other Characterized Proteins Similar to cysK

Finding the characterized proteins for cysK (O-acetylserine or O-succinylserine sulfhydrylase) in L-cysteine biosynthesis

Or see clustering for step cysK

Or see all steps for L-cysteine biosynthesis

Or cluster curated proteins matching a keyword

Definition of cysK

Fetched 63 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 47 other characterized sequences. (Found 110 hits including self hits.)

Removing ignored items reduces this to 45 close sequences.

There are also 6 HMM-only high-coverage hits.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for cysK.)

CYSD_EMENI / P50125 Homocysteine synthase; O-acetylhomoserine sulfhydrylase; OAH SHL; OAH sulfhydrylase; EC 2.5.1.49 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
GI|2605905 O-acetylhomoserine (thiol)-lyase; EC 2.5.1.49 from Emericella nidulans
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Beta_elim_lyase, Aminotran_1_2, Aminotran_5
437 amino acids: PaperBLAST, CDD, CharProtDB::CH_122447
64% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

CYSD_SCHPO / O13326 Homocysteine synthase; O-acetylhomoserine sulfhydrylase; OAH SHL; OAH sulfhydrylase; EC 2.5.1.49 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
RF|NP_595189.1 homocysteine synthase Met17; EC 2.5.1.49 from Schizosaccharomyces pombe
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
429 amino acids: PaperBLAST, CDD, CharProtDB::CH_124469
63% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

FUB7_GIBM7 / W7MS09 Sulfhydrylase FUB7; Fusaric acid biosynthesis protein 7; EC 2.5.1.- from Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
433 amino acids: PaperBLAST, CDD, SwissProt::W7MS09
57% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

FUB7_FUSO4 / A0A0D2YG02 Sulfhydrylase FUB7; Fusaric acid biosynthesis protein 7; EC 2.5.1.- from Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) (Fusarium vascular wilt of tomato)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
433 amino acids: PaperBLAST, CDD, SwissProt::A0A0D2YG02
57% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

FUB7_GIBF5 / S0DUX5 Sulfhydrylase FUB7; Fusaric acid biosynthesis protein 7; EC 2.5.1.- from Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae and foot rot disease fungus) (Fusarium fujikuroi)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
433 amino acids: PaperBLAST, CDD, SwissProt::S0DUX5
57% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

MCCA_BACSU / O05393 O-acetylserine dependent cystathionine beta-synthase; EC 2.5.1.134 from Bacillus subtilis (strain 168)
PFams: PALP
307 amino acids: PaperBLAST, CDD, SwissProt::O05393
56% identical to

F9UT54 cysteine synthase (EC 2.5.1.47); cystathionine beta-synthase (EC 4.2.1.22) from Lactiplantibacillus plantarum
PFams: PALP
303 amino acids: PaperBLAST, CDD

METY_THEMA / Q9WZY4 O-acetyl-L-homoserine sulfhydrylase; OAH sulfhydrylase; O-acetylhomoserine thiolase; EC 2.5.1.- from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
430 amino acids: PaperBLAST, CDD, SwissProt::Q9WZY4
54% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

METY1_THET8 / Q5SK88 O-acetyl-L-homoserine sulfhydrylase 1; OAH-sulfhydrylase 1; EC 2.5.1.- from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2
421 amino acids: PaperBLAST, CDD, SwissProt::Q5SK88
50% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

L7N4M1 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) from Mycobacterium tuberculosis
PFams: Cys_Met_Meta_PP
449 amino acids: PaperBLAST, CDD, BRENDA::L7N4M1
48% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

Q9EYM7 cysteine-S-conjugate beta-lyase (EC 4.4.1.13) from Streptomyces venezuelae
PFams: PALP, CBS
463 amino acids: PaperBLAST, CDD, BRENDA::Q9EYM7
48% identical to

Q84IF9 cysteine synthase (EC 2.5.1.47); L-3-cyanoalanine synthase (EC 4.4.1.9) from Geobacillus stearothermophilus
PFams: PALP
308 amino acids: PaperBLAST, CDD

Y1077_MYCTU / P9WP51 Probable cystathionine beta-synthase Rv1077; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: PALP, CBS, CBS
464 amino acids: PaperBLAST, CDD, SwissProt::P9WP51
46% identical to

CYSK_MYCTU / P9WP55 O-acetylserine sulfhydrylase; OAS sulfhydrylase; OASS; Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine-specific cysteine synthase; Sulfide-dependent cysteine synthase; EC 2.5.1.47 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WP55 cysteine synthase (EC 2.5.1.47) from Mycobacterium tuberculosis
PFams: PALP
310 amino acids: PaperBLAST, CDD

LOLC1_EPIUN / Q8J0B2 Sulfhydrylase-like protein lolC1; Loline biosynthesis cluster 1 protein C; EC 2.5.1.- from Epichloe uncinata (Endophyte fungus) (Neotyphodium uncinatum)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Aminotran_5
473 amino acids: PaperBLAST, CDD, SwissProt::Q8J0B2
45% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

LOLC2_EPIUN / Q5MNH8 Sulfhydrylase-like protein lolC2; Loline biosynthesis cluster 2 protein C; EC 2.5.1.- from Epichloe uncinata (Endophyte fungus) (Neotyphodium uncinatum)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Aminotran_5
473 amino acids: PaperBLAST, CDD, SwissProt::Q5MNH8
45% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

P94890 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) from Leptospira meyeri
METY_LEPME / P94890 O-acetyl-L-homoserine sulfhydrylase; OAH-sulfhydrylase; EC 2.5.1.- from Leptospira meyeri
P94890 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) from Leptospira meyeri
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1
442 amino acids: PaperBLAST, CDD, BRENDA::P94890
45% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

CH_122414 cystathionine beta-synthase; EC 4.2.1.22 from Emericella nidulans
PFams: PALP, CBS
533 amino acids: PaperBLAST, CDD, CharProtDB::CH_122414
44% identical to

E5LPF4 cysteine synthase (EC 2.5.1.47) from Lacticaseibacillus casei
PFams: PALP
309 amino acids: PaperBLAST, CDD

CBS_APIME / Q2V0C9 Cystathionine beta-synthase; EC 4.2.1.22 from Apis mellifera (Honeybee)
Q2V0C9 cystathionine beta-synthase (EC 4.2.1.22) from Apis mellifera
PFams: PALP
504 amino acids: PaperBLAST, CDD, BRENDA::Q2V0C9
46% identical to

W5S3I4 cysteine synthase (EC 2.5.1.47) from Leucaena leucocephala
PFams: PALP
325 amino acids: PaperBLAST, CDD

Q187D4 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) from Clostridioides difficile
PFams: Cys_Met_Meta_PP
421 amino acids: PaperBLAST, CDD, BRENDA::Q187D4
44% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

Q2RWB7 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)
PFams: Cys_Met_Meta_PP
438 amino acids: PaperBLAST, CDD, metacyc::MONOMER-17873
43% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

Q9VRD9 cystathionine beta-synthase (EC 4.2.1.22) from Drosophila melanogaster
PFams: PALP, CBS
522 amino acids: PaperBLAST, CDD, BRENDA::Q9VRD9
42% identical to

CYSK_MYCTU / P9WP55 O-acetylserine sulfhydrylase; OAS sulfhydrylase; OASS; Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine-specific cysteine synthase; Sulfide-dependent cysteine synthase; EC 2.5.1.47 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WP55 cysteine synthase (EC 2.5.1.47) from Mycobacterium tuberculosis
PFams: PALP
310 amino acids: PaperBLAST, CDD

P32232 cystathionine β-synthase subunit (EC 4.2.1.22) from Rattus norvegicus
CBS_RAT / P32232 Cystathionine beta-synthase; Beta-thionase; Hemoprotein H-450; Serine sulfhydrase; EC 4.2.1.22 from Rattus norvegicus (Rat)
PFams: PALP, CBS
561 amino acids: PaperBLAST, CDD, SwissProt::P32232
43% identical to

Q2PZM5 cysteine synthase (EC 2.5.1.47) from Azospirillum brasilense
PFams: PALP
319 amino acids: PaperBLAST, CDD

A0A563XPB1 cystathionine β-synthase (EC 4.2.1.22) from Gallus gallus
PFams: PALP, CBS
524 amino acids: PaperBLAST, CDD, metacyc::MONOMER-22007
42% identical to

W5S3I4 cysteine synthase (EC 2.5.1.47) from Leucaena leucocephala
PFams: PALP
325 amino acids: PaperBLAST, CDD

Q79VI4 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
METY_CORGL / Q79VI4 O-acetyl-L-homoserine sulfhydrylase; OAH-sulfhydrylase; EC 2.5.1.49 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1
437 amino acids: PaperBLAST, CDD, SwissProt::Q79VI4
42% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

P35520 cystathionine β-synthase monomer (EC 4.2.1.22) from Homo sapiens
CBS_HUMAN / P35520 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Homo sapiens (Human)
P35520 cystathionine beta-synthase (EC 4.2.1.22) from Homo sapiens
PFams: PALP, CBS
551 amino acids: PaperBLAST, CDD, BRENDA::P35520
42% identical to

Q2PZM5 cysteine synthase (EC 2.5.1.47) from Azospirillum brasilense
PFams: PALP
319 amino acids: PaperBLAST, CDD

A0A220K8J3 L-3-cyanoalanine synthase (EC 4.4.1.9) from Aporia crataegi
PFams: PALP
325 amino acids: PaperBLAST, CDD, BRENDA::A0A220K8J3
42% identical to

CGL_ARATH / F4K5T2 Bifunctional cystathionine gamma-lyase/cysteine synthase; Beta-substituted Ala synthase 4;3; ARAth-Bsas4;3; L-cysteine desulfhydrase 1; DES1; O-acetylserine (thiol)-lyase; OASTL; Protein CS-LIKE; EC 2.5.1.47; EC 4.4.1.1 from Arabidopsis thaliana (Mouse-ear cress)
F4K5T2 L-cysteine desulfidase (EC 4.4.1.28) from Arabidopsis thaliana
PFams: PALP
323 amino acids: PaperBLAST, CDD

A0A220K819 L-3-cyanoalanine synthase (EC 4.4.1.9) from Colias croceus
PFams: PALP
334 amino acids: PaperBLAST, CDD, BRENDA::A0A220K819
41% identical to

CGL_ARATH / F4K5T2 Bifunctional cystathionine gamma-lyase/cysteine synthase; Beta-substituted Ala synthase 4;3; ARAth-Bsas4;3; L-cysteine desulfhydrase 1; DES1; O-acetylserine (thiol)-lyase; OASTL; Protein CS-LIKE; EC 2.5.1.47; EC 4.4.1.1 from Arabidopsis thaliana (Mouse-ear cress)
F4K5T2 L-cysteine desulfidase (EC 4.4.1.28) from Arabidopsis thaliana
PFams: PALP
323 amino acids: PaperBLAST, CDD

A0A220K813 L-3-cyanoalanine synthase (EC 4.4.1.9) from Spodoptera littoralis
PFams: PALP
335 amino acids: PaperBLAST, CDD, BRENDA::A0A220K813
40% identical to

A3RM06 cysteine synthase (EC 2.5.1.47) from Glycine max
PFams: PALP
324 amino acids: PaperBLAST, CDD

Q7M844 O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) from Wolinella succinogenes
PFams: Cys_Met_Meta_PP, Aminotran_1_2
422 amino acids: PaperBLAST, CDD, BRENDA::Q7M844
40% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

CBS2_CAEEL / Q9N4K2 Putative cystathionine beta-synthase cbs-2; EC 4.2.1.22 from Caenorhabditis elegans
PFams: PALP, PALP
662 amino acids: PaperBLAST, CDD, SwissProt::Q9N4K2
40% identical to

CYSK_MYCTU / P9WP55 O-acetylserine sulfhydrylase; OAS sulfhydrylase; OASS; Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine-specific cysteine synthase; Sulfide-dependent cysteine synthase; EC 2.5.1.47 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WP55 cysteine synthase (EC 2.5.1.47) from Mycobacterium tuberculosis
PFams: PALP
310 amino acids: PaperBLAST, CDD

A0A220K8H3 L-3-cyanoalanine synthase (EC 4.4.1.9) from Gonepteryx rhamni
PFams: PALP
325 amino acids: PaperBLAST, CDD, BRENDA::A0A220K8H3
41% identical to

A3RM06 cysteine synthase (EC 2.5.1.47) from Glycine max
PFams: PALP
324 amino acids: PaperBLAST, CDD

T1KF23 L-3-cyanoalanine synthase (EC 4.4.1.9) from Tetranychus urticae
PFams: PALP
320 amino acids: PaperBLAST, CDD, BRENDA::T1KF23
42% identical to

A0A2Z6G0Q7 mimosine synthase monomer (EC 2.5.1.47; EC 2.5.1.52) from Leucaena leucocephala
A0A2Z6G0Q7 cysteine synthase (EC 2.5.1.47) from Leucaena leucocephala
PFams: PALP
324 amino acids: PaperBLAST, CDD

A0A220K8E3 L-3-cyanoalanine synthase (EC 4.4.1.9) from Colias croceus
PFams: PALP
326 amino acids: PaperBLAST, CDD, BRENDA::A0A220K8E3
40% identical to

A2GMG5 cysteine synthase (EC 2.5.1.47) from Trichomonas vaginalis
PFams: PALP
299 amino acids: PaperBLAST, CDD

A0A220K8A8 L-3-cyanoalanine synthase (EC 4.4.1.9) from Zygaena filipendulae
PFams: PALP
329 amino acids: PaperBLAST, CDD, BRENDA::A0A220K8A8
42% identical to

CGL_ARATH / F4K5T2 Bifunctional cystathionine gamma-lyase/cysteine synthase; Beta-substituted Ala synthase 4;3; ARAth-Bsas4;3; L-cysteine desulfhydrase 1; DES1; O-acetylserine (thiol)-lyase; OASTL; Protein CS-LIKE; EC 2.5.1.47; EC 4.4.1.1 from Arabidopsis thaliana (Mouse-ear cress)
F4K5T2 L-cysteine desulfidase (EC 4.4.1.28) from Arabidopsis thaliana
PFams: PALP
323 amino acids: PaperBLAST, CDD

A0A220K835 L-3-cyanoalanine synthase (EC 4.4.1.9) from Spodoptera littoralis
PFams: PALP
332 amino acids: PaperBLAST, CDD, BRENDA::A0A220K835
40% identical to

A3RM06 cysteine synthase (EC 2.5.1.47) from Glycine max
PFams: PALP
324 amino acids: PaperBLAST, CDD

A0A0U3S5Y4 L-3-cyanoalanine synthase (EC 4.4.1.9) from Pieris rapae
PFams: PALP
325 amino acids: PaperBLAST, CDD, BRENDA::A0A0U3S5Y4
41% identical to

A3RM06 cysteine synthase (EC 2.5.1.47) from Glycine max
PFams: PALP
324 amino acids: PaperBLAST, CDD

P32582 Cys4 (EC 4.2.1.22) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CBS_YEAST / P32582 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; Sulfur transfer protein 4; EC 4.2.1.22 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P32582 cystathionine beta-synthase (EC 4.2.1.22) from Saccharomyces cerevisiae
PFams: PALP, CBS
507 amino acids: PaperBLAST, CDD, BRENDA::P32582
40% identical to

Q9XEA8 cysteine synthase (EC 2.5.1.47) from Oryza sativa Japonica Group
PFams: PALP
325 amino acids: PaperBLAST, CDD

A0A0U3QZ45 L-3-cyanoalanine synthase (EC 4.4.1.9) from Pieris rapae
PFams: PALP
326 amino acids: PaperBLAST, CDD, BRENDA::A0A0U3QZ45
41% identical to

E5LPF4 cysteine synthase (EC 2.5.1.47) from Lacticaseibacillus casei
PFams: PALP
309 amino acids: PaperBLAST, CDD

A0A220K8D1 L-3-cyanoalanine synthase (EC 4.4.1.9) from Anthocharis cardamines
PFams: PALP
326 amino acids: PaperBLAST, CDD, BRENDA::A0A220K8D1
40% identical to

A3RM06 cysteine synthase (EC 2.5.1.47) from Glycine max
PFams: PALP
324 amino acids: PaperBLAST, CDD

A0A220K8D2 L-3-cyanoalanine synthase (EC 4.4.1.9) from Aporia crataegi
PFams: PALP
324 amino acids: PaperBLAST, CDD, BRENDA::A0A220K8D2
40% identical to

A2GMG5 cysteine synthase (EC 2.5.1.47) from Trichomonas vaginalis
PFams: PALP
299 amino acids: PaperBLAST, CDD

A0A0U3SCD8 L-3-cyanoalanine synthase (EC 4.4.1.9) from Pieris rapae
PFams: PALP
325 amino acids: PaperBLAST, CDD, BRENDA::A0A0U3SCD8
40% identical to

A2GMG5 cysteine synthase (EC 2.5.1.47) from Trichomonas vaginalis
PFams: PALP
299 amino acids: PaperBLAST, CDD

A0A220K8C9 L-3-cyanoalanine synthase (EC 4.4.1.9) from Anthocharis cardamines
PFams: PALP
325 amino acids: PaperBLAST, CDD, BRENDA::A0A220K8C9
40% identical to

A3RM06 cysteine synthase (EC 2.5.1.47) from Glycine max
PFams: PALP
324 amino acids: PaperBLAST, CDD

A0A220K8F1 L-3-cyanoalanine synthase (EC 4.4.1.9) from Aporia crataegi
PFams: PALP
326 amino acids: PaperBLAST, CDD, BRENDA::A0A220K8F1
40% identical to

E5LPF4 cysteine synthase (EC 2.5.1.47) from Lacticaseibacillus casei
PFams: PALP
309 amino acids: PaperBLAST, CDD

A0A220K8B9 L-3-cyanoalanine synthase (EC 4.4.1.9) from Plutella xylostella
PFams: PALP
322 amino acids: PaperBLAST, CDD, BRENDA::A0A220K8B9
40% identical to

CYSD1_ARATH / Q9S6Z7 Bifunctional L-3-cyanoalanine synthase/cysteine synthase D1; Beta-substituted Ala synthase 4;1; ARAth-Bsas4;1; Cysteine synthase D1; AtcysD1; O-acetylserine (thiol)-lyase 3; EC 2.5.1.47; EC 4.4.1.9 from Arabidopsis thaliana (Mouse-ear cress)
PFams: PALP
324 amino acids: PaperBLAST, CDD

METX_YEAST / Q04533 Putative cystathionine gamma-synthase YML082W; O-succinylhomoserine (thiol)-lyase; EC 2.5.1.48 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP
649 amino acids: PaperBLAST, CDD, SwissProt::Q04533
41% identical to

METW_YEAST / Q12198 Homocysteine/cysteine synthase; Hydrogen sulfide utilizing 1; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP
575 amino acids: PaperBLAST, CDD

CH_122042 cystathionine gamma-synthase (Eurofung) from Emericella nidulans
PFams: Cys_Met_Meta_PP
594 amino acids: PaperBLAST, CDD, CharProtDB::CH_122042
41% identical to

METW_YEAST / Q12198 Homocysteine/cysteine synthase; Hydrogen sulfide utilizing 1; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP
575 amino acids: PaperBLAST, CDD

MET7_SCHPO / O74314 Probable cystathionine gamma-synthase; O-succinylhomoserine (thiol)-lyase; EC 2.5.1.48 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: Cys_Met_Meta_PP
610 amino acids: PaperBLAST, CDD, SwissProt::O74314
42% identical to

METW_YEAST / Q12198 Homocysteine/cysteine synthase; Hydrogen sulfide utilizing 1; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP
575 amino acids: PaperBLAST, CDD

HMM-only sequences

(Since these sequences' annotations are outside the definition for cysK, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)

Q1KLZ2 β-cyanoalanine synthase (EC 4.4.1.9) from Malus domestica
CAS1_MALDO / Q1KLZ2 L-3-cyanoalanine synthase 1, mitochondrial; MdCAS1; EC 4.4.1.9 from Malus domestica (Apple) (Pyrus malus)
Q1KLZ2 L-3-cyanoalanine synthase (EC 4.4.1.9) from Malus domestica
PFams: PALP
376 amino acids: PaperBLAST, CDD

J9WJN8 L-cysteine desulfidase (EC 4.4.1.28) from Brassica napus
PFams: PALP
323 amino acids: PaperBLAST, CDD

Q1KLZ1 β-cyanoalanine synthase (EC 4.4.1.9) from Malus domestica
CAS2_MALDO / Q1KLZ1 L-3-cyanoalanine synthase 2, mitochondrial; MdCAS2; EC 4.4.1.9 from Malus domestica (Apple) (Pyrus malus)
Q1KLZ1 L-3-cyanoalanine synthase (EC 4.4.1.9) from Malus domestica
PFams: PALP
375 amino acids: PaperBLAST, CDD

Q8L0X3 L-cysteine desulfhydrase (EC 4.4.1.1) from Fusobacterium nucleatum
Q8L0X3 L-cysteine desulfidase (EC 4.4.1.28) from Fusobacterium nucleatum
PFams: PALP
306 amino acids: PaperBLAST, CDD

I1L6I6 L-3-cyanoalanine synthase (EC 4.4.1.9) from Glycine max
PFams: PALP
373 amino acids: PaperBLAST, CDD

P9WP53 CysO-thiocarboxylate-dependent cysteine synthase monomer (EC 2.5.1.113) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
CYSM_MYCTU / P9WP53 O-phosphoserine sulfhydrylase; OPS sulfhydrylase; CysO-thiocarboxylate-dependent cysteine synthase; Cysteine synthase B; CSase B; O-phosphoserine-specific cysteine synthase; [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase; EC 2.5.1.113 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WP53 [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase (EC 2.5.1.113); O-phosphoserine sulfhydrylase (EC 2.5.1.65) from Mycobacterium tuberculosis
PFams: PALP
323 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for cysK.)

CH_123612 O-acetylhomoserine O-acetylserine sulphydrylase from Candida albicans
PFams: Cys_Met_Meta_PP, DegT_DnrJ_EryC1, Aminotran_1_2, Aminotran_5
440 amino acids: PaperBLAST, CDD, CharProtDB::CH_123612
69% identical to

P06106 Met17 (EC 2.5.1.49) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
CYSD_YEAST / P06106 Homocysteine/cysteine synthase; O-acetylserine/O-acetylhomoserine sulfhydrylase; OAS-OAH SHLase; OAS-OAH sulfhydrylase; EC 2.5.1.47; EC 2.5.1.49 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Cys_Met_Meta_PP, Aminotran_1_2, Beta_elim_lyase, DegT_DnrJ_EryC1, Aminotran_5
444 amino acids: PaperBLAST, CDD

O22682 S-sulfocysteine synthase (EC 2.5.1.144) from Arabidopsis thaliana
CYSK4_ARATH / O22682 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic; AtCS26; Beta-substituted Ala synthase 5;1; ARAth-Bsas5;1; O-acetylserine sulfhydrylase; EC 2.5.1.144 from Arabidopsis thaliana (Mouse-ear cress)
O22682 cysteine synthase (EC 2.5.1.47) from Arabidopsis thaliana
PFams: PALP
404 amino acids: PaperBLAST, CDD, BRENDA::O22682
63% identical to

Q9XEA8 cysteine synthase (EC 2.5.1.47) from Oryza sativa Japonica Group
PFams: PALP
325 amino acids: PaperBLAST, CDD