GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for aceA (isocitrate lyase) in glycine biosynthesis

Or see other characterized proteins similar to aceA

Or see all steps for glycine biosynthesis

Or cluster curated proteins matching a keyword

Definition of aceA

Fetched 42 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 39 of these sequences

Found 4 clusters of similar sequences. Another 3 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 518-766 amino acids (not heteromeric)

Q5YLB6 isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase
537 amino acids: PaperBLAST, CDD, Compare to cluster

Q9P8Q7 isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase
550 amino acids: PaperBLAST, CDD, Compare to cluster

CH_090747 methylisocitrate lyase precursor; EC 4.1.3.30
CH_122270 methylisocitrate lyase; EC 4.1.3.30 (from HMM only)
PFams: ICL, PEP_mutase
604 amino acids: PaperBLAST, CDD, Compare to cluster

P28298 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30
CH_122014 isocitrate lyase; EC 4.1.3.1
PFams: ICL, PEP_mutase
538 amino acids: PaperBLAST, CDD, Compare to cluster

CH_123497 Isocitrate lyase (from HMM only)
PFams: ICL, PEP_mutase
550 amino acids: PaperBLAST, CDD, Compare to cluster

P0CT06 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30
CH_124286 isocitrate lyase
PFams: ICL, PEP_mutase
547 amino acids: PaperBLAST, CDD, Compare to cluster

C8V9Y5 Methylisocitrate lyase, mitochondrial; 2-methylisocitrate lyase, mitochondrial; EC 4.1.3.30 (from HMM only)
PFams: ICL, PEP_mutase
610 amino acids: PaperBLAST, CDD, Compare to cluster

G9NNY7 2-methylisocitrate lyase, mitochondrial; EC 4.1.3.30 (from HMM only)
PFams: ICL
561 amino acids: PaperBLAST, CDD, Compare to cluster

H8F3R6 Isocitrate lyase 2; ICL2; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC 4.1.3.1; EC 4.1.3.30
Q8VJU4 Isocitrate lyase 2; ICL2; Isocitrase; Isocitratase; EC 4.1.3.1
PFams: ICL, PEP_mutase, ICL
766 amino acids: PaperBLAST, CDD, Compare to cluster

P25248 Isocitrate lyase; ICL; Isocitrase; Isocitratsysase; EC 4.1.3.1
PFams: ICL, PEP_mutase
576 amino acids: PaperBLAST, CDD, Compare to cluster

P28240 Isocitrate lyase; ICL; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30
PFams: ICL, PEP_mutase
557 amino acids: PaperBLAST, CDD, Compare to cluster

P28297 Isocitrate lyase; ICL; Isocitrase; Isocitratsysase; EC 4.1.3.1
PFams: ICL, PEP_mutase
576 amino acids: PaperBLAST, CDD, Compare to cluster

P28299 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30
PFams: ICL, PEP_mutase
548 amino acids: PaperBLAST, CDD, Compare to cluster

P41555 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30
PFams: ICL, PEP_mutase
540 amino acids: PaperBLAST, CDD, Compare to cluster

Q12031 Mitochondrial 2-methylisocitrate lyase; Methylisocitrate lyase; EC 4.1.3.30 (from HMM only)
PFams: ICL, PEP_mutase
575 amino acids: PaperBLAST, CDD, Compare to cluster

Q6BZP5 2-methylisocitrate lyase, mitochondrial; EC 4.1.3.30 (from HMM only)
PFams: ICL, PEP_mutase
565 amino acids: PaperBLAST, CDD, Compare to cluster

Q6Z6M4 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1
PFams: ICL, PEP_mutase
572 amino acids: PaperBLAST, CDD, Compare to cluster

Q86ZF1 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30
PFams: ICL, PEP_mutase
537 amino acids: PaperBLAST, CDD, Compare to cluster

Q8NJ72 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30
PFams: ICL, PEP_mutase
542 amino acids: PaperBLAST, CDD, Compare to cluster

Q9P6J1 Mitochondrial 2-methylisocitrate lyase; Methylisocitrate lyase; EC 4.1.3.30 (from HMM only)
PFams: ICL, PEP_mutase
518 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 428-528 amino acids (not heteromeric)

P42449 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1
PFams: ICL, PEP_mutase, ICL
432 amino acids: PaperBLAST, CDD, Compare to cluster

A8C5K8 isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL, ICL
528 amino acids: PaperBLAST, CDD, Compare to cluster

E4W8P2 isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL
429 amino acids: PaperBLAST, CDD, Compare to cluster

H8EVV4 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC 4.1.3.1; EC 4.1.3.30
P0A5H4 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; EC 4.1.3.1
P9WKK6 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC 4.1.3.1; EC 4.1.3.30
P9WKK7 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1
P9WKK7 isocitrate lyase (EC 4.1.3.1)
G185E-4594-MONOMER isocitrate lyase subunit (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL
428 amino acids: PaperBLAST, CDD, Compare to cluster

Q8RPZ0 isocitrate lyase (EC 4.1.3.1)
PFams: ICL, ICL
436 amino acids: PaperBLAST, CDD, Compare to cluster

Q97YI8 isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL
437 amino acids: PaperBLAST, CDD, Compare to cluster

ISOCIT-LYASE-MONOMER isocitrate lyase (EC 4.1.3.1)
P0A9G6 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1
PFams: ICL, PEP_mutase, ICL
434 amino acids: PaperBLAST, CDD, Compare to cluster

Koxy:BWI76_RS01665 Isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL
434 amino acids: PaperBLAST, CDD, Compare to cluster

MR1:200655 Isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL
440 amino acids: PaperBLAST, CDD, Compare to cluster

PV4:5208774 Isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL
450 amino acids: PaperBLAST, CDD, Compare to cluster

SB2B:6938260 Isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL
439 amino acids: PaperBLAST, CDD, Compare to cluster

acidovorax_3H11:Ac3H11_2831 Isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL
443 amino acids: PaperBLAST, CDD, Compare to cluster

pseudo1_N1B4:Pf1N1B4_4042 Isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL
441 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 531-540 amino acids (not heteromeric)

A8C781 isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL, ICL
531 amino acids: PaperBLAST, CDD, Compare to cluster

Q9I0K4 isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL, ICL
531 amino acids: PaperBLAST, CDD, Compare to cluster

O50078 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1
PFams: ICL, PEP_mutase, ICL, ICL
540 amino acids: PaperBLAST, CDD, Compare to cluster

psRCH2:GFF1971 Isocitrate lyase (EC 4.1.3.1)
PFams: ICL, PEP_mutase, ICL, ICL
531 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 318-345 amino acids (not heteromeric)

Q05957 Petal death protein; Citramalate lyase; Oxalacetic hydrolase; PSR132; EC 3.7.1.1; EC 4.1.3.22
Q05957 isocitrate lyase (EC 4.1.3.1)
PFams: PEP_mutase, ICL
318 amino acids: PaperBLAST, CDD, Compare to cluster

D4GTL3 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1
PFams: PEP_mutase, ICL, ICL
345 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/3 heteromeric)

Q8LPA6 isocitrate lyase (EC 4.1.3.1)
PFams: Malate_synthase, HpcH_HpaI, ICL, ICL
1165 amino acids: PaperBLAST, CDD

P28467 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1
CH_017389 isocitrate lyase; EC 4.1.3.1
15 amino acids: PaperBLAST, CDD

Q10663 Bifunctional glyoxylate cycle protein; Gex-3-interacting protein 7; EC 4.1.3.1; EC 2.3.3.9
PFams: ICL, PEP_mutase, ICL, Malate_synthase
968 amino acids: PaperBLAST, CDD